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196841“…Metformin is an anti-diabetic agent that manages hyperglycemia but has also been shown to have a beneficial effect on stem cells after injury. …”
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196842por Li, Yuanfeng, Yang, Guang, Ren, Yijin, Shi, Linqi, Ma, Rujiang, van der Mei, Henny C., Busscher, Henk J.“…Furthermore, specific patient groups possessing elevated levels of endogenous substrate (for instance, diabetic or cancer patients) may benefit from the use of cascade reaction components containing nanocarriers.…”
Publicado 2020
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196843por Souza, Carlos E., Lima, Luiz H., Nascimento, Heloísa, Zett, Claudio, Belfort, Rubens“…Secondary outcomes included Early Treatment Diabetic Retinopathy Study (ETDRS), best-corrected visual acuity (BCVA) and adverse events. …”
Publicado 2020
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196844por Zhang, Lingshu, Song, Pingfang, Zhang, Xiaowei, Metea, Christina, Schleisman, Matthew, Karstens, Lisa, Leung, Eric, Zhang, Jun, Xu, Qiang, Liu, Yi, Asquith, Mark, Chu, Cong-Qiu“…Acarose is an anti-diabetic drug and exhibits anti-arthritic effects. …”
Publicado 2020
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196845por McAloon, Christopher J, Hyndman, Samantha, Ansell, Valerie, O'Hare, Paul, Randeva, Harpal, Osman, Faizel“…RESULTS: Twenty-five patients were recruited; mean-age (±SD) was 73.4±10.0 years, 23 males, 18 CRT defibrillators (remainder CRT pacemakers), 16 had ischaemic aetiology, 6 diabetics, 17 with left bundle-branch morphology on ECG and 10 had atrial fibrillation. …”
Publicado 2020
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196846“…Notably, Sirt2 protects many organs from various injuries, including diabetic peripheral neuropathy. As demonstrated previously by our laboratory and others, the overexpression of Sirt2 can improve cisplatin-induced neuropathy, although the mechanism is still unclear. …”
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196847por Wilkins, Carl S, Mehta, Neesurg, Wu, Chris Y, Barash, Alexander, Deobhakta, Avnish A, Rosen, Richard B“…The most common aetiology was exudative macular degeneration (43.2%), followed by undifferentiated choroidal neovascularisation (CNV) (18.9%), polypoidal choroidal vasculopathy (18.9%), traumatic CNV (10.8%), macroaneurysm (5.4%) and proliferative diabetic retinopathy (2.7%). Median preoperative VA was 20/2000, postoperative month 1 was 20/347 (p<0.01), improving to 20/152 (p<0.01) at month 3. …”
Publicado 2020
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196848por Tanimoto, Yuji, Yamasaki, Tomoteru, Nagoshi, Narihito, Nishiyama, Yuichiro, Nori, Satoshi, Nishimura, Soraya, Iida, Tsuyoshi, Ozaki, Masahiro, Tsuji, Osahiko, Ji, Bin, Aoki, Ichio, Jinzaki, Masahiro, Matsumoto, Morio, Fujibayashi, Yasuhisa, Zhang, Ming‐Rong, Nakamura, Masaya, Okano, Hideyuki“…The current study was conducted to visualize Nestin (an NS/PC marker)‐positive undifferentiated neural cells in the CNS of immune‐deficient (nonobese diabetic‐severe combined immune‐deficient) mice after hiPSC‐NS/PCs transplantation with PET, using 18 kDa translocator protein (TSPO) ligands as labels. …”
Publicado 2020
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196849por Coelho, Teresa, Yarlas, Aaron, Waddington-Cruz, Marcia, White, Michelle K., Sikora Kessler, Asia, Lovley, Andrew, Pollock, Michael, Guthrie, Spencer, Ackermann, Elizabeth J., Hughes, Steven G., Karam, Chafic, Khella, Sami, Gertz, Morie, Merlini, Giampaolo, Obici, Laura, Schmidt, Hartmut H., Polydefkis, Michael, Dyck, P. James B., Brannagan III, Thomas H., Conceição, Isabel, Benson, Merrill D., Berk, John L.“…At baseline and week 66, QOL measures—the Norfolk-QOL-Diabetic Neuropathy (DN) questionnaire and SF-36v2(®) Health Survey (SF-36v2)—were assessed. …”
Publicado 2019
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196850por Banerjee, Debasish, Popoola, Joyce, Shah, Sapna, Ster, Irina Chis, Quan, Virginia, Phanish, Mysore“…Three patients with severe disease were diabetic. During a three week follow up one patient recovered, and one patient died. …”
Publicado 2020
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196851por Gale, Richard P, Pearce, Ian, Eter, Nicole, Ghanchi, Faruque, Holz, Frank G, Schmitz-Valckenberg, Steffen, Balaskas, Konstantinos, Burton, Ben J L, Downes, Susan M, Eleftheriadis, Haralabos, George, Sheena, Gilmour, David, Hamilton, Robin, Lotery, Andrew J, Patel, Nishal, Prakash, Priya, Santiago, Cynthia, Thomas, Saju, Varma, Deepali, Walters, Gavin, Williams, Michael, Wolf, Armin, Zakri, Rosina H, Igwe, Franklin, Ayan, Filis“…Improvements were also observed in other quantitative and qualitative optical coherence tomography parameters. In Early Treatment Diabetic Retinopathy Study letters assessed by category, 55% and 59% of patients gained 0–≥15 letters versus baseline at day 90 and day 180, respectively. …”
Publicado 2020
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196852por Tahkola, Aapo, Korhonen, Päivi, Kautiainen, Hannu, Niiranen, Teemu, Mäntyselkä, Pekka“…METHODS: In this observational cross-sectional study, based on routine electronic health record (EHR) data, we investigated LDL-C control of hypertensive, non-diabetic patients without renal dysfunction or CVD, aged 30 years or more in Finnish primary care setting. …”
Publicado 2020
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196853por Farinha, Cláudia, Santos, Torcato, Santos, Ana Rita, Lopes, Marta, Alves, Dalila, Silva, Rufino, Cunha-Vaz, José“…Best-corrected visual acuity was assessed using Early Treatment Diabetic Retinopathy Study method. Optical coherence tomography leakage maps depicting low optical reflectivity (LOR) sites were acquired with OCT Cirrus AngioPlex (Zeiss, Dublin, CA). …”
Publicado 2020
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196854por Miquelestorena-Standley, Elodie, Jaulerry, Charlotte, Machet, Marie-Christine, Rabot, Nolwenn, Barbet, Christelle, Hummel, Aurélie, Karras, Alexandre, Garrouste, Cyril, Crepin, Thomas, Ducloux, Didier, Cousin, Maud, Albert, Catherine, Rivalan, Joseph, Cornec-Le Gall, Emilie, Pourreau, François, Deltombe, Clément, Nochy, Dominique, Szlavik, Nora, Felix, Sophie, Croué, Anne, Buob, David, Rioux-Leclerc, Nathalie, Doucet, Laurent, Goujon, Jean-Michel, Renaudin, Karine, Blanchard, Emmanuelle, Eymieux, Sébastien, Rabant, Marion, Halimi, Jean-Michel“…Twenty-one (78%) had Staphylococcus aureus infection and twelve (44%) were diabetic. At the time of biopsy, 95.2% had haematuria, 48.1% had a serum creatinine level of > 4 mg/dL, and 16% had hypocomplementemia. …”
Publicado 2020
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196855por Zhang, Ying-Li, Wang, Jie-Min, Yin, Hong, Wang, Shou-Bao, He, Cai-Ling, Liu, Jing“…OBJECTIVE: This report was designed to assess the functional role of miR-218/dachshund family transcription factor 1 (DACH1) in diabetic kidney disease (DKD) and investigate its possible molecular mechanism. …”
Publicado 2020
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196856por Hu, Ruimin, Quan, Songxia, Wang, Yingzi, Zhou, Yali, Zhang, Ying, Liu, Lu, Zhou, Xin J., Xing, Guolan“…The same trend appeared with membranoproliferative glomerulonephritis (MPGN), diabetic nephropathy (DN) and obesity-related glomerulopathy (ORG), while the frequencies of minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), LN and hepatitis B associated glomerulonephritis (HBV-GN) significantly decreased between the two intervals. …”
Publicado 2020
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196857por Pasquarelli-do-Nascimento, Gabriel, Braz-de-Melo, Heloísa Antoniella, Faria, Sara Socorro, Santos, Igor de Oliveira, Kobinger, Gary P., Magalhães, Kelly Grace“…Taken together, it may be crucial to better explore the role of visceral adipose tissue in the inflammatory response to SARS-CoV-2 infection and investigate the potential therapeutic effect of using specific target anti-inflammatories (canakinumab or anakinra for IL-1β inhibition; anti-IL-6 antibodies for IL-6 inhibition), anticoagulant or anti-diabetic drugs in COVID-19 treatment of people with obesity. …”
Publicado 2020
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196858por Etingen, Bella, Patrianakos, Jamie, Wirth, Marissa, Hogan, Timothy P, Smith, Bridget M, Tarlov, Elizabeth, Stroupe, Kevin T, Kartje, Rebecca, Weaver, Frances M“…BACKGROUND: Chronic wounds, such as pressure injuries and diabetic foot ulcers, are a significant predictor of mortality. …”
Publicado 2020
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196859por Tada, Seiichiro, Anazawa, Takayuki, Shindo, Takero, Yamane, Kei, Inoguchi, Kenta, Fujimoto, Nanae, Nagai, Kazuyuki, Masui, Toshihiko, Okajima, Hideaki, Takaori, Kyoichi, Sumi, Shoichiro, Uemoto, Shinji“…Islets from fully major histocompatibility complex-mismatched BALB/c mice were transplanted into streptozotocin-induced diabetic C57BL/6 mice via the portal vein. These mice received trametinib or vehicle (orally) for 28 days. …”
Publicado 2020
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196860por Dai, Haoran, Liu, Fei, Qiu, Xinping, Liu, Wenbin, Dong, Zhaocheng, Jia, Yingmin, Feng, Zhendong, Liu, Zhiyuan, Zhao, Qihan, Gao, Yu, Zhang, Zihan, Gao, Chang, Sun, Songge, Tian, Xuefei, Liu, Baoli“…Many studies have shown that the pathogenesis of diabetic kidney disease (DKD) is related to the excessive activation of the Wnt/β-catenin signaling pathway on podocytes, so the treatment of DKD starts from this signaling pathway. …”
Publicado 2020
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