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  1. 196861
    por Yan, Ting, Zhang, Zhihui, Li, Danqing
    Publicado 2020
    “…BACKGROUND: Glucose fluctuation promotes neuronal apoptosis, which plays a central role in diabetic encephalopathy (DE). Nerve growth factor (NGF), and its interaction with high-affinity (TrkA) and low-affinity (p75NTR) receptors, are involved in neuronal survival. …”
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    NGF receptors and PI3K/AKT pathway involved in glucose fluctuation-induced damage to neurons and α-lipoic acid treatment
  2. 196862
    por Koike, Haruki, Katsuno, Masahisa
    Publicado 2020
    “…The thickening or reduplication of the basement membrane surrounding endoneurial microvessels, which is similar to diabetic neuropathy, is observed in ATTRv amyloidosis, suggesting that common mechanisms, such as an accumulation of advanced glycation end products, may participate in the disease process. …”
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    Transthyretin Amyloidosis: Update on the Clinical Spectrum, Pathogenesis, and Disease-Modifying Therapies
  3. 196863
    “…PURPOSE: To evaluate the initial ten years of results from the intravitreal dexamethasone implant (DEX) in patients treated for retinal vein occlusion (RVO), diabetic macular edema (DME) or uveitis. METHODS: Retrospective chart review of patients receiving DEX since its FDA approval. …”
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    Initial Ten Years of Experience with the Intravitreal Dexamethasone Implant: A Retrospective Chart Review
  4. 196864
    “…During this period, there was a progressive decrease of cardiovascular disease hospital costs per year (from 2834 Euros in 2015 to 2146 Euros in 2019, P < 0.001), as well as cardiovascular and diabetic medication costs. CONCLUSIONS: During the 2015–2019 period, costs of HF patients in Spain were substantial, being HF hospitalizations the most important determinant. …”
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    Costs and healthcare utilisation of patients with heart failure in Spain
  5. 196865
    “…Exclusion criteria were prospective studies that (1) exclusively recruited diseased patients (eg, hypertensive patients and diabetics) or (2) did not account for total physical activity in their multivariable models (3) or did not adjust or exclude individuals with comorbidities at baseline or (4) used physically inactive participants as reference group. …”
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    Do vigorous-intensity and moderate-intensity physical activities reduce mortality to the same extent? A systematic review and meta-analysis
  6. 196866
    “…ACE2 was highly and significantly expressed in the kidney among individuals with chronic kidney diseases or diabetic nephropathy. In single cells, ACE2 was primarily enriched in gametocytes in the testis and renal proximal tubules. …”
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    Multiple Expression Assessments of ACE2 and TMPRSS2 SARS-CoV-2 Entry Molecules in the Urinary Tract and Their Associations with Clinical Manifestations of COVID-19
  7. 196867
    por Huang, Chienhsiu
    Publicado 2020
    “…RESULTS: Sixty-one cases of Alcaligenes faecalis infection were seen during the study period, including 25 cases of cystitis, nine cases of diabetic foot infection, eight cases of pneumonia, seven cases of acute pyelonephritis, three cases of bacteremia, and nine cases of infection at specific sites. …”
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    Extensively drug-resistant Alcaligenes faecalis infection
  8. 196868
    “…No other demographic (age, sex), environmental (solitary/non-solitary housing, professional and physical activities, smoking, alcohol drinking), comorbidity (antipsychotic drug uptake, diabetic state) and type of surgery (orthopedic, general, genitourinary) influenced the development of PND. …”
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    Preoperative sedentary behavior is neither a risk factor for perioperative neurocognitive disorders nor associated with an increase in peripheral inflammation, a prospective observational cohort study
  9. 196869
    por Ahn, Sung-Ho, Lee, Jun-Hyuk, Lee, Ji-Won
    Publicado 2020
    “…METHODS: This study included 15,741 non-diabetic adults over 19 years old using data from the 2008–2011 Korea National Health and Nutrition Examination Survey. …”
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    Inverse association between triglyceride glucose index and muscle mass in Korean adults: 2008–2011 KNHANES
  10. 196870
    “…CONCLUSIONS: The glucose level of patients who are diabetic and obese/overweight can be improved by supplementation with chitosan for at least 13 weeks at 1.6–3 g per day. …”
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    Chitosan modifies glycemic levels in people with metabolic syndrome and related disorders: meta-analysis with trial sequential analysis
  11. 196871
    “…Factors that increase the risk of non-participation are: being men (OR = 1.10, 95% CI 1.09–1.12); younger than 60 (OR = 1.18, 95% CI 1.17–1.20); smoker (OR = 1.20, 95% CI 1.18–1.22); hypertensive (OR = 1.14, 95% CI 1.12–1.15) and diabetic (OR = 1.40, 95% CI 1.36–1.43); having severe comorbidity (OR = 2.09, 95% CI 2.00–2.19) and very high deprivation (OR = 1.15, 95% CI 1.12–1.17), as well as making <6 appointments to Primary Care in 3 years (OR = 2.39, 95% CI 2.33–2.45). …”
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    Factors Related to Non-participation in the Basque Country Colorectal Cancer Screening Programme
  12. 196872
    “…Efficacy was measured by improvement seen in best-corrected visual acuity (BCVA) in terms of Early Treatment of Diabetic Retinopathy Study (ETDRS) Letter Scores and change in central retinal thickness (CRT) measured by optical coherence tomography. …”
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    Sub-optimal gain in vision in retinal vein occlusion due to under-treatment in the real world: results from an open-label prospective study of Intravitreal Ranibizumab
  13. 196873
    “…We recently showed in non-diabetic Mexican American (MA) children that serum α-carotene and β-carotene are inversely correlated with obesity measures and triglycerides and positively with HDL cholesterol and that they were under strong genetic influences. …”
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    Serum carotenoids and Pediatric Metabolic Index predict insulin sensitivity in Mexican American children
  14. 196874
    “…The BCVAs were measured as decimal values and converted to the corresponding Early Treatment Diabetic Retinopathy Study (ETDRS) letter scores for statistical analysis. …”
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    Four-year outcomes of intravitreal aflibercept treatment for neovascular age-related macular degeneration using a treat-and-extend regimen in Japanese patients
  15. 196875
    “…However, diastolic Ca(2+) impairments, including reduced sarco/endoplasmic reticulum Ca(2+)-ATPase activity, were specifically observed in diabetic HFpEF but not in ischemic or hypertensive models. …”
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    Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
  16. 196876
    “…Three hundred fifty patients completed the study (138 diabetic foot ulcers, 106 venous leg ulcers, 60 surgical sites, 22 pressure ulcers, and 24 others). …”
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    Diagnostic Accuracy of Point-of-Care Fluorescence Imaging for the Detection of Bacterial Burden in Wounds: Results from the 350-Patient Fluorescence Imaging Assessment and Guidance Trial
  17. 196877
    “…In nondiabetic patients, achievement of all 3 targets including blood pressure ≤130/80 mm Hg, renin-angiotensin aldosterone system inhibition, and dietary advice, ranged from 10% in the United States to 32% in Brazil; in treated diabetic patients, this ranged from 6% to 11% after including hemoglobin A1c target. …”
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    Adherence to the Kidney Disease: Improving Global Outcomes CKD Guideline in Nephrology Practice Across Countries
  18. 196878
    “…Metabolism of xylitol is insulin independent and thus it is an ideal sweetener for diabetics. It is widely used in food products, oral and personal care, and animal nutrition as well. …”
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    Production of bio-xylitol from d-xylose by an engineered Pichia pastoris expressing a recombinant xylose reductase did not require any auxiliary substrate as electron donor
  19. 196879
    “…The introduction of Met, a conventional anti-diabetic drug, promotes programmed death-ligand 1 (PD-L1) degradation by activating adenosine monophosphate-activated protein kinase, subsequently blocking the inhibitory signals of PD-L1. …”
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    Regulating the immunosuppressive tumor microenvironment to enhance breast cancer immunotherapy using pH-responsive hybrid membrane-coated nanoparticles
  20. 196880
    “…RESULTS: In the study group (mean age 55.6± 15.1 years; 73 % men, 36% diabetic and 86% hypertensive), low and highly protective vaccine responses were seen in 32% and 50% respectively versus 18% of patient had a lack of seroconversion. …”
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    Response to single dose hepatitis B vaccine in Congolese non-HIV hemodialysis patients: a prospective observational study
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