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198001por Ramírez Medina, Carlos R., Ali, Ibrahim, Baricevic-Jones, Ivona, Odudu, Aghogho, Saleem, Moin A., Whetton, Anthony D., Kalra, Philip A., Geifman, Nophar“…This provides further evidence to target complement inhibition as a potential approach to modulating the progression of diabetic nephropathy. Proteins involved in the ubiquitin–proteasome pathway, a crucial protein degradation system, were also found to be significantly enriched. …”
Publicado 2023
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198002por Hoffmann, Laura, Müller, Susanne, Bachmann, Lucas M, Claessens, Daniela, Hatz, Katja“…Location of mCNV was graded using the Early Treatment of Diabetic Retinopathy Study grid overlay. A usability questionnaire was administered at 12 months. …”
Publicado 2023
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198003por Bidin, F.N., Chow, T.S., Wong, P.S., Leong, K.N., Lim, C.H., Looi, C.L., Chin, J.Z., Chuah, C.H.“…The secondary outcomes are duration of mechanical ventilation, length of ICU stays and rate of complications such as acute kidney injury, sepsis, bleeding tendency and diabetic ketoacidosis. FINDINGS: A total of 100 patients were included in the analysis, whom 64% were male, mean age of 56.6 (SD 13.4) and 53% have at least one comorbidity. …”
Publicado 2023
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198004por Sidhwani, Santosh Kumar, Mirza, Talat, Khatoon, Ambrina, Shaikh, Fouzia, Khan, Rizma, Shaikh, Omer Ahmed, Nashwan, Abdulqadir J.“…Males of old age and diabetics are found to have more severe COVID-19 infection in the current study. …”
Publicado 2023
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198005por Dieke, Sebastian, Wurche, Stefanie, Ruebsam, Anne, Wirbelauer, Christopher, Joussen, Antonia M., Winterhalter, Sibylle“…PURPOSE: The study aims to evaluate changes in contrast sensitivity (CS) during therapy with intravitreal vascular endothelial growth factor (VEGF) inhibitors in patients with neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME). METHODS: Prospective, uncontrolled, multicenter study on patients with neovascular AMD or DME who underwent intravitreal injection therapy with Ranibizumab, Aflibercept, or Bevacizumab was conducted. …”
Publicado 2023
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198006por LoBue, Stephen A, Gindina, Sofya, Saba, Nicholas J, Chang, Tom, Davis, Michael J, Fish, Steven“…METHODS: This was a three-month, prospective study of patients receiving outpatient IVI of anti-VEGF agents for diabetic retinopathy (DR), age-related macular degeneration (AMD), and retinal vein occlusion (RVO) at the Acuity Eye Group Medical Centers. …”
Publicado 2023
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198007por Marriott, A. E., Dagley, J. L., Hegde, S., Steven, A., Fricks, C., DiCosty, U., Mansour, A., Campbell, E. J., Wilson, C. M., Gusovsky, F., Ward, S. A., Hong, W. D., O'Neill, P., Moorhead, A., McCall, S., McCall, J. W., Taylor, M. J., Turner, J. D.“…METHODS: As a refined alternative in vivo heartworm preventative drug screen, we assessed lymphopenic mouse strains with ablation of the interleukin-2/7 common gamma chain (γc) as susceptible to the larval development phase of Dirofilaria immitis. RESULTS: Non-obese diabetic (NOD) severe combined immunodeficiency (SCID)γc(−/−) (NSG and NXG) and recombination-activating gene (RAG)2(−/−)γc(−/−) mouse strains yielded viable D. immitis larvae at 2–4 weeks post-infection, including the use of different batches of D. immitis infectious larvae, different D. immitis isolates, and at different laboratories. …”
Publicado 2023
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198008por Shimamoto, Yuki, Sasaki, Hirohito, Kasuno, Kenji, Watanabe, Yuki, Sakashita, Sayumi, Nishikawa, Sho, Nishimori, Kazuhisa, Morita, Sayu, Nishikawa, Yudai, Kobayashi, Mamiko, Fukushima, Sachiko, Enomoto, Soichi, Takahashi, Naoki, Hamano, Tadanori, Sakamaki, Ippei, Iwasaki, Hiromichi, Iwano, Masayuki“…She had developed end-stage kidney disease (ESKD) secondary to diabetic nephropathy. Seven days prior to admission, she had developed fever and was diagnosed with COVID-19. …”
Publicado 2023
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198009por Wan, Yiming, Zhang, Ziliang, Ling, Yong, Cui, Hui, Tao, Zihan, Pei, Jianfeng, Maimaiti, Aikedan, Bai, Haifan, Wu, Yiling, Li, Jing, Zhao, Genming, Zaid, Maryam“…In subgroup analyses, younger (< 50y) and diabetic participants had higher risk of CVD than their counterpart groups, while hypertensive and dyslipidemic participants depicted lower risks than their counterparts. …”
Publicado 2023
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198010por Raman, Sainath, Rahiman, Sarfaraz, Kennedy, Melanie, Mattke, Adrian, Venugopal, Prem, McBride, Craig, Tu, Quyen, Zapf, Florian, Kuhlwein, Eva, Woodgate, Jemma, Singh, Puneet, Schlapbach, Luregn J, Gibbons, Kristen S“…Patients with tumour lysis syndrome, diabetic ketoacidosis or postorgan transplant are excluded. …”
Publicado 2023
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198011por Hong, Young Joon, Jeong, Myung Ho, Choi, Yun Ha, Cho, Suk Hee, Hwang, Seung Hwan, Ko, Jum Suk, Lee, Min Goo, Park, Keun Ho, Sim, Doo Sun, Yoon, Nam Sik, Yoon, Hyun Ju, Kim, Kye Hun, Park, Hyung Wook, Kim, Ju Han, Ahn, Youngkeun, Cho, Jeong Gwan, Park, Jong Chun, Kang, Jung Chaee“…RESULTS: The highest tertile group was mostly diabetics (20%, 27%, 40%, p=0.009), and had the greatest plaque plus media volume (163±139/mm(3) vs. 201±155/mm(3) vs. 232±176/mm(3), p=0.013). …”
Publicado 2011
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198012por Previato, Mariana, Frederico, Fábio Batista, Henrique Antunes Murata, Fernando, Siqueira, Rubens Camargo, Barbosa, Amanda Pires, Silveira-Carvalho, Aparecida Perpétuo, da Silva Meira, Cristina, Pereira-Chioccola, Vera Lúcia, Gava, Ricardo, Pereira Martins Neto, Plínio, de Mattos, Luiz Carlos, Brandão de Mattos, Cinara Cássia“…The clinical evaluation was performed by ophthalmologic examination using the Early Treatment Diabetic Retinopathy Study, best-corrected visual acuity, slit lamp biomicroscopy, fundoscopic examination with indirect binocular ophthalmoscopy color fundus photography, fluorescein angiography and spectral optical coherence tomography (OCT). …”
Publicado 2015
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198013por Martinez, Carlos H., Freeman, Christine M., Nelson, Joshua D., Murray, Susan, Wang, Xin, Budoff, Matthew J., Dransfield, Mark T., Hokanson, John E., Kazerooni, Ella A., Kinney, Gregory L., Regan, Elizabeth A., Wells, J. Michael, Martinez, Fernando J., Han, MeiLan K., Curtis, Jeffrey L.“…This association was maintained after additionally adjusting for baseline CVD risk, for co-morbidities and descriptors of COPD severity and impact, markers of cardiac stress (N-terminal pro–B-type natriuretic peptide, troponin T) and of inflammation (Interleukin-6), and in subgroup analysis excluding men, diabetics, current smokers or those with limited ambulation. …”
Publicado 2017
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198014por Song, Kang-Kang, Zhao, De-Long, Wang, Yuan-Da, Wang, Yong, Sun, Xue-Feng, Miao, Li-Ning, Ni, Zhao-Hui, Lin, Hong-Li, Liu, Fu-You, Li, Ying, He, Ya-Ni, Wang, Nian-Song, Wang, Cai-Li, Zhang, Ai-Hua, Chen, Meng-Hua, Yang, Xiao-Ping, Deng, Yue-Yi, Shao, Feng-Min, Fu, Shu-Xia, Fang, Jing-Ai, Cai, Guang-Yan, Chen, Xiang-Mei“…Compared with the survival group, the death group had more men and more patients with diabetic nephropathy (DN) and hypertensive nephropathy. …”
Publicado 2017
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198015por Wang, Ping, Cong, Min, Liu, Tianhui, Xu, Hufeng, Wang, Lin, Sun, Guangyong, Yang, Aiting, Zhang, Dong, Huang, Jian, Sun, Yameng, Zhao, Wenshan, Ma, Hong, Jia, Jidong, You, Hong“…METHODS: The effects of HNF4α on rat hepatic progenitors (i.e. hepatic oval cells) were analyzed by HNF4α overexpression and HNF4α shRNA. Nonobese diabetic/severe combined immunodeficiency (NOD/SCID) mice injured by carbon chloride (CCl(4)) were then transplanted with control, HNF4α-overexpressing or HNF4α-suppressing hepatic oval cells. …”
Publicado 2017
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198016por Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Allebrandt, Karla Viviani, Brorsson, Caroline, van Leeuwen, Nienke, Banasik, Karina, Mahajan, Anubha, Groves, Christopher J., van de Bunt, Martijn, Dawed, Adem Y., Fritsche, Andreas, Staiger, Harald, Simonis-Bik, Annemarie M. C., Deelen, Joris, Kramer, Mark H. H., Dietrich, Axel, Hübschle, Thomas, Willemsen, Gonneke, Häring, Hans-Ulrich, de Geus, Eco J. C., Boomsma, Dorret I., Eekhoff, Elisabeth M. W., Ferrer, Jorge, McCarthy, Mark I., Pearson, Ewan R., Gupta, Ramneek, Brunak, Søren, ‘t Hart, Leen M.“…We performed the first genome-wide association study (GWAS) of GLP-1 stimulated insulin secretion in non-diabetic individuals from the Netherlands Twin register (n = 126). …”
Publicado 2018
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198017por Mohsen, Ala, Alqasrawi, Musab, Shantha, Ghanshyam Palamaner Subash, DeZorzi, Chris, Panaich, Sidakpal“…Mean age: 65 years, men: 63%, diabetics: 37%. SG was associated with lower RAO at band removal [unadjusted (OR: 0.31, 95% CI: 0.21–0.46), adjusted (OR: 0.10, 95% CI: 0.05–0.20) and propensity matched (OR: 0.20, 95% CI: 0.13–0.32)], at 24 hours [unadjusted (OR: 0.20, 95% CI: 0.12–0.34), adjusted (OR: 0.12, 95% CI: 0.06–0.24) and propensity matched (OR: 0.13, 95% CI: 0.07–0.25)] and 30 days [unadjusted (OR: 0.28, 95% CI: 0.14–0.54), adjusted (OR: 0.22, 95% CI: 0.10–0.50) and propensity matched (OR: 0.18, 95% CI: 0.10–0.40)], compared to SLG. …”
Publicado 2018
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198018por Hehemann, Marah, Choe, Shawn, Kalmanek, Elizabeth, Harrington, Daniel, Stupp, Samuel I., McVary, Kevin T., Podlasek, Carol A.“…Urinary incontinence affects 40% of elderly men, is common in diabetic patients and in men treated for prostate cancer, with a prevalence of up to 44%. …”
Publicado 2018
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198019por Rapacciuolo, Antonio, Mancusi, Costantino, Canciello, Grazia, Izzo, Raffaele, Strisciuglio, Teresa, de Luca, Nicola, Ammirati, Giuseppe, de Simone, Giovanni, Trimarco, Bruno, Losi, Maria-Angela“…At baseline, 956 (15%) patients exhibited high CHA(2)DS(2)-VASc; they were older, most likely to be women, obese and diabetic, with lower glomerular filtration rate, and higher prevalence of left ventricular hypertrophy, left-atrial dilatation and carotid plaque (all p < 0.005). …”
Publicado 2019
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198020por Ohji, Masahito, Takahashi, Kanji, Okada, Annabelle A., Kobayashi, Masato, Matsuda, Yoshimi, Terano, Yasuhiro“…METHODS: Adults aged at least 50 years old with exudative AMD and best-corrected visual acuity (BCVA) of 73–25 Early Treatment Diabetic Retinopathy Study (ETDRS) letters were included. …”
Publicado 2020
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