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72641por He, Huan, Liao, Qibin, Zhao, Chen, Zhu, Cuisong, Feng, Meiqi, Liu, Zhuoqun, Jiang, Lang, Zhang, Linxia, Ding, Xiangqing, Yuan, Min, Zhang, Xiaoyan, Xu, Jianqing“…BACKGROUND: Hypoxia is a striking feature of most solid tumors and could be used to discriminate tumors from normoxic tissues. Therefore, the design of hypoxia-conditioned Chimeric Antigen Receptor (CAR) T cells is a promising strategy to reduce on-target off-tumor toxicity in adoptive cell therapy. …”
Publicado 2021
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72642por Nov, Tam, Hyodo, Toru, Kitajima, Yukie, Kokubo, Kenichi, Naganuma, Toshihide, Wakai, Haruki, Yamashita, Akihiro, Phon, Elin, Kawanishi, Hideki“…Some healthcare workers have been discriminated against by neighbors. The most difficult mission is when having to deal with families whose loved one is denied access to a hemodialysis session due to suspected COVID-19 while waiting for PCR test results. …”
Publicado 2021
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72643“…Breadth of global health content across curricular was a major discriminating factor between institutions, and we would advise universities to consider including more global health topics across their curricular - especially in light of the intersectional impacts of the COVID-19 pandemic.…”
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72644por Ringwald, Aleida, Goetz, Katja, Steinhaeuser, Jost, Fleischmann, Nina, Schüssler, Alexandra, Flaegel, Kristina“…Descriptive item analysis, factor analysis, internal consistency and convergent, discriminant and predictive validity of the German instrument versions were calculated by using SPSS 25.0 (Inc., IBM). …”
Publicado 2021
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72645por Moonen, Hanneke PFX., Bos, Anneloes E., Hermans, Anoek JH., Stikkelman, Eline, van Zanten, Florianne JL., van Zanten, Arthur RH.“…An ROC-curve showed that the incorporation of PhA in a composite risk-score improved the discriminative power for the composite outcome from poor to fair, compared to individual predictors (AUC 0.79 (95% CI 0.71–0.87)). …”
Publicado 2021
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72646por Sserumaga, Julius Pyton, Kayondo, Siraj Ismail, Kigozi, Abasi, Kiggundu, Muhammad, Namazzi, Clementine, Walusimbi, Kato, Bugeza, James, Molly, Allen, Mugerwa, Swidiq“…These markers had a low discriminating ability with mean polymorphic information content (P.I.C.) of 0.14 with DArTseq-based SNPs and 0.13 with SilicoDart markers. …”
Publicado 2021
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72647por Mostovenko, Ekaterina, Dahm, Matthew M., Schubauer-Berigan, Mary K., Eye, Tracy, Erdely, Aaron, Young, Tamara L., Campen, Matthew J., Ottens, Andrew K.“…Peptide biomarker model building and refinement employed linear regression and partial least squared discriminant analyses. Top-ranked peptides were then sequence identified and evaluated for pathological-relevance. …”
Publicado 2021
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72648por Ruan, Guo-Tian, Yang, Ming, Zhang, Xiao-Wei, Song, Meng-Meng, Hu, Chun-Lei, Ge, Yi-Zhong, Xie, Hai-Lun, Liu, Tong, Tang, Meng, Zhang, Qi, Zhang, Xi, Zhang, Kang-Ping, Li, Xiang-Rui, Li, Qin-Qin, Chen, Yong-Bing, Yu, Kai-Ying, Cong, Ming-Hua, Wang, Kun-Hua, Shi, Han-Ping“…CONCLUSION: The prognostic and discriminative value of the inflammatory indicator ALI was better than that of NLR, PNI, SII, and PLR in EPCC. …”
Publicado 2021
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72649por Rivadeneira, María Fernanda, Mendieta, María José, Villavicencio, Jessica, Caicedo-Gallardo, José, Buendía, Patricio“…It proposes to evaluate the intrinsic capacity of the individual, the social and political environment and the interaction with it, through indicators that discriminate who are ageing in a healthy way and who are not. …”
Publicado 2021
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72650por Tufail, Ahsan Bin, Ma, Yong-Kui, Zhang, Qiu-Na, Khan, Adil, Zhao, Lei, Yang, Qiang, Adeel, Muhammad, Khan, Rahim, Ullah, Inam“…CONCLUSION: The proposed model provides a good performance in discriminating AD and PD subjects due to minimal correlation between these two dementia types on the clinicopathological continuum between AD and PD subjects from a neuroimaging perspective.…”
Publicado 2021
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72651por Saputro, Sigit Ari, Pattanaprateep, Oraluck, Pattanateepapon, Anuchate, Karmacharya, Swekshya, Thakkinstian, Ammarin“…Cox and logit regression) were mostly applied, otherwise machine learning. In cohorts, the discriminative performance in derived-logit was pooled with C statistics of 0.82 (0.73‑0.92) for DR and 0.78 (0.74‑0.83) for CKD. …”
Publicado 2021
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72652por Cai, Xin-Tian, Zhu, Qing, Liu, Sha-Sha, Wang, Meng-Ru, Wu, Ting, Hong, Jing, Hu, Jun-Li, Li, Nanfang“…Time-dependent receiver operating curve suggested helpful discriminative power of the METS-IR index for T2DM. The C-statistics by the clinical risk factors significantly improve with the addition of the METS-IR index (from 0.862 to 0.875, P = 0.035); the discriminatory power and risk reclassification also appeared to be substantially better, with the category-free NRI of 0.216, and the IDI of 0.011. …”
Publicado 2021
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72653por Fukuhara, Hideo, Nohara, Takahiro, Nishimoto, Koshiro, Hatakeyama, Yutaka, Hyodo, Yuki, Okuhara, Yoshiyasu, Oyama, Masafumi, Mizokami, Atsushi, Inoue, Keiji, Matsuyama, Hideyasu“…Decision tree analysis showed presence of general anesthesia, age ≥ 74 years and American Society of Anesthesiologists physical status (ASA-PS) ≥2 as the most important discriminators. CONCLUSIONS: General anesthesia and hypertension were independent risk factors related to ALA-induced hypotension. …”
Publicado 2021
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72654por Fritzsche, Kurt, Shi, Lili, Löhlein, Johanna, Wei, Jing, Sha, Yue, Xie, Yongbiao, He, Yanling, Tschuschke, Volker, Flatten, Guido, Wang, Yibo, Jin, Chen, Leonhart, Rainer“…The verification of the construct validity of the BGQ-C showed satisfying convergent (r(s) = .465 to .574) and discriminant validity (r(s) = -.117 to -.209). The model was tested with a confirmatory factor analysis of a three-factor model (standardized root mean square residual = .025; comparative fit index = .977; Tucker-Lewis index = .971). …”
Publicado 2021
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72655por Schramm, Sara, Jokisch, Martha, Jöckel, Karl-Heinz, Herring, Arne, Keyvani, Kathy“…With an AUC of 0.92 (0.86–0.97), blood KLK8 was a strong discriminator for aMCI and CU. CONCLUSION: This is the first population-based study to demonstrate the potential clinical utility of blood KLK8 as a biomarker for incipient AD. …”
Publicado 2021
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72656por Junek, Mats L., Jones, Aaron, Heckman, George, Demers, Catherine, Griffith, Lauren E., Costa, Andrew P.“…Functional status also had a graded relationship with each outcome and improved the discriminability of the models predicting death and LTCF readiness (p<0.01) but not ED re-presentation or hospital re-admission. …”
Publicado 2022
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72657por Zang, Lele, Chen, Qin, Zhang, Xiaozhen, Zhong, Xiaohong, Chen, Jian, Fang, Yi, Lin, An, Wang, Min“…Harrell’s concordance index, receiver operating characteristic curve, calibration plot were used to evaluate the discriminability and accuracy of the predictive models, and decision curve analysis (DCA) was used to show the net benefits. …”
Publicado 2021
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72658por Wang, Shujing, Zhu, Hua, Li, Yingjie, Ding, Jin, Wang, Feng, Ding, Lixin, Wang, Xinyu, Zhao, Jun, Zhang, Yan, Yao, Yunfeng, Zhou, Tong, Li, Nan, Wu, Aiwen, Yang, Zhi“…An SUV(max) of 9.3 at 48 hours and 6.3 at 72 hours could be used to discriminate the DR5 expression status of tumors both with a sensitivity and specificity of 100% and 92.9%, respectively. …”
Publicado 2021
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72659“…LAP and CMI exhibited larger AUCs, compared to other obesity-related indexes in terms of discriminating NAFLD. The AUCs of LAP and CMI were 0.860 (95%CI = 0.852–0.867) and 0.833 (95%CI = 0.825–0.842) in women and 0.816 (95%CI = 0.806–0.825) and 0.779 (95%CI = 0.769–0.789) in men. …”
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72660por Chen, Chi Chiung Grace, Long, Annelise, Rwabizi, Denis, Mbabazi, Gerard, Ndizeye, Ntwali, Dushimiyimana, Blaise, Ngoga, Eugene“…We evaluated the discriminative ability of the questionnaire using a case–control study design in a 1:2:2 ratio: cases were parous women with fistula confirmed on examination, controls included parous women without fistula on examination, with and without UI symptoms. …”
Publicado 2022
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