“…PURPOSE: We wanted to test the effects from atrial pacing (AP) compared to sinus rhythm (SR) on Td in animals with narrow QRS (nQRS) complexes and after the creation of LBBB. METHODS: 9 mongrel dogs were included in the study and handled according to ethics committee approved protocol/GLP. …”
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“…However, despite progress, this species still has a much higher anesthesia-related mortality than dogs and cats. Rabbits are prey animals that tend to hide signs of pain, which makes it particularly difficult to assess and to treat it adequately. …”
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“…The mean time to improvement was 2.1 days in TL-IVDE (range from 1 day to 4 days). All dogs that did not improve (5/39) were grade 5 TL-IVDEs at presentation. …”
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“…METHODS: In a prospective, randomized, experimental study, 18 healthy, large, deep-chested, mixed-breed intact female dogs were randomly allocated to conventional (n = 9) and instrument shank-assisted (n = 9) groups. …”
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“…It is challenging to completely rule out the possibility of reverse zoonotic transmission from humans to livestock in Korea, although the transmission is not to the same extent as it is in highly susceptible animal species like minks, cats, and dogs. This is due to the limited geographical area and the dense, intensive farming practices implemented in these regions. …”
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“…BACKGROUND: The transfection of human mesenchymal stem cells (hMSCs) with the hyperpolarization-activated cyclic nucleotide-gated ion channel 2 (HCN2) gene has been demonstrated to provide biological pacing in dogs with complete heart block. The mechanism appears to be the generation of the ion current (I(f)) by the HCN2-expressing hMSCs. …”
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“…Furthermore, the amount of records on dogs, cats and humans indicate that ticks were acquired locally, presenting a local biting risk. …”
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“…Vehicles that were transporting pigs, sheep, or goats were more likely to have the poorest welfare conditions, whilst vehicles that were transporting horses or other species, including dogs, were often found with irregular documentation. …”
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“…When adjusted for under-detection due to non-participating hospitals and province-level demographic differences, the estimated suspected rabies exposure rate was 204/100,000. Dogs were the main source of exposure (77.8%) and children age <15 years and elderly age >60 years had the highest overall reported exposure rate (189.7 and 189.2/100,000). …”
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“…We investigated the pharmacokinetics (PK) of a GLP-1 analogue (liraglutide) delivered over a single 24h period using the wearable h-Patch™ subcutaneous infusion device in dogs. Liraglutide (1800ug) was infused at a static rate over 24h delivered with PK evaluated at time points to 72h from the start of infusion. …”
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“…It has been reported in cattle, dogs, mice and rats. Until now, eight pathogenic variants in the bovine ectodysplasin A (EDA) gene causing ECTD1-like disorders have been found. …”
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“…All patients had pets either dogs or cats at home and no pets had been dewormed. …”
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“…On the other hand, VSPs are presently considered as key vaccine candidates because they induce protection against Giardia in rodents and dogs. Overall, this review reveals that much more work is needed to identify, characterize, and understand the roles of virulence factors in Giardia and to assess their validity as drug and vaccine targets. …”
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“…The review is focused mainly on several clinical trials conducted in humans and companion dogs with cancer treated with hyperthermia and radiotherapy. …”
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“…By virtue of their possible involvement in neoplastic transformation and progression, investigated miRNAs may represent candidate biomarkers with prognostic relevance in dogs with mammary tumors. ABSTRACT: MicroRNAs (miRNAs) can act as oncogenes or oncosuppressor genes, and their involvement in nearly all cancer-associated processes makes these small molecules promising diagnostic and prognostic biomarkers in cancer, as well as specific targets for cancer therapy. …”
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“…This suggests leopard cats use a proactive strategy to avoid human encounters, which was supported by the reduced temporal overlap with humans and domestic dogs on agricultural land. Resting sites were placed ca. 1 km apart, 12.9 ± 0.3 m (mean ± SE) from the patch’s edges, in patches with a size of 1.21 ± 0.04 ha (mean ± SE). …”
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“…Collip pointed out that young normal dogs are more susceptible to parathormone (6). This observation was corroborated by Morgan and Garrison (7). …”
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“…PURPOSE: We wanted to analyze the measurement from QRS-onset to onset of LV pressure rise identified as the peak double derivative of LV pressure rise (Onset of Synergy, OoS) and to the peak pressure rise (Td), and test the effects of cardiac resynchronization therapy with endocardial vs epicardial pacing electrodes in a large animal model of LBBB. METHODS: 5 mongrel dogs were included in the study and handled according to ethics committee approved protocol/GLP. …”
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“…The commonly used semi-automatic software 4D-AutLVQ™ showed underestimation of LV volumes in comparison with CMRI in healthy anesthetized dogs (Am J Vet Res 74(9):1223–1230, 2013). TomTec 4D LV-Function™ is an offline analysis program for morphological and functional analyses of the left ventricle by using manual measurement optimization, showing excellent agreement with CMRI in human medicine (Echocardiography 27(10):1263–1273, 2010; Eur J Echocardiogr 11(4):359–368, 2010; Echocardiography 24(9):967–974, 2007). …”
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“…RESULTS: Some of the identified strengths of ebola virus include: Ebola virus is an RNA virus with inherent capability to mutate, reassort and recombine to generate mutant or reassortant virulent strains; Ebola virus has a broad cellular tropism; Natural Reservoir of ebola virus is unconfirmed but fruit bats, arthropods, and plants are hypothesized; Ebola virus primarily targets and selectively destroys the immune system; Ebola viruses possess accessory proteins that inhibits the host’ immune responses; Secreted glycoprotein (sGP), a truncated soluble protein that triggers immune activation and increased vascular permeability is uniquely associated with Ebola virus only; Ability to effectively cross the species barrier and establish productive infection in humans, non human primates, and other mammals; Ebola virus attacks every part of the human body; The Weaknesses include: Ebola virus transmission and persistence is severely limited by its virulence; Ebola virus essentially requires host encoded protein Niemann–Pick C1 (NPC1) for host’s cell’ entry; Ebola virus essentially requires host encoded proteins (TIM-1) for cell’ entry; Relative abundance of Ebolavirus Nucleoprotein than the other virion components; The Opportunities harnessed by ebola virus include: Lack of infection control practices in African health-care facilities and paucity of health infrastructures, especially in the endemic zones; Permissiveness of circulating Monocytes, Macrophages and dendritic cells in virus mobilization and dissemination; Collection, consumption and trade of wild games (bushmeats); Pertubation and drastic changes in forest ecosystems present opportunities for Ebola virus; Use of dogs in hunting predisposes man and animals to inter-species contact; Poverty, malnutrition, crowding, social disorder, mobility and political instability; Ease of travel and aviation as potentials for global spread; Possible mechanical transmission by arthropod vectors; No vaccines or therapeutics are yet approved for human treatment; The Threats to ebola virus include: Avoidance of direct contact with infected blood and other bodily fluids of infected patient; Appropriate and correct burial practices; Adoption of barrier Nursing; Improved surveillance to prevent potential spread of epidemic; Making Available Rapid laboratory equipment and procedures for prompt detection (ELISA, Western Blot, PCR); Sterilization or disinfection of equipment and safe disposal of instrument; Prompt hospitalization, isolation and quarantine of infected individual; Active contact tracing and monitoring, among others. …”
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