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41“…We aim to compare the efficacy and safety of concurrent chemotherapy using taxane plus cisplatin [double-agent concurrent chemotherapy (DACC) group] with those of cisplatin alone [single-agent concurrent chemotherapy (SACC) group] in high-risk LANPC. …”
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42por Wang, Xin, Han, Weiming, Zhang, Wencheng, Wang, Xiaomin, Ge, Xiaolin, Lin, Yu, Zhou, Haiwen, Hu, Miaomiao, Wang, Wei, Liu, Ke, Lu, Jianchao, Qie, Shuai, Zhang, Jihong, Deng, Wei, Wang, Lan, Han, Chun, Li, Minghe, Zhang, Kaixian, Li, Ling, Wang, Qifeng, Shi, Hongyun, Yu, Zhilong, Zhao, Yidian, Sun, Xinchen, Shi, Yonggang, Pang, Qingsong, Zhou, Zongmei, Liang, Jun, Chen, Dongfu, Feng, Qinfu, Bi, Nan, Zhang, Tao, Deng, Lei, Wang, Wenqing, Liu, Wenyang, Wang, Jianyang, Zhai, Yirui, Wang, Junjie, Chen, Wanqing, Chen, Junqiang, Xiao, Zefen“…IMPORTANCE: Double-agent intravenous chemotherapy concurrent with radiotherapy is the standard of care for patients with inoperable esophageal cancer. …”
Publicado 2023
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43“…Traditionally, DH production requires the use of chemical doubling agents to induce haploid genome doubling and, subsequently, male fertility. …”
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44“…This callus-based technique could be employed when a genome-doubling agent generated mixoploids, but no tetraploids.…”
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45“…The resulting haploid plants are treated with a doubling agent and self-pollinated, producing completely homozygous seeds. …”
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46por Yu, Ping, Petrus, Michael N., Ju, Wei, Zhang, Meili, Conlon, Kevin C., Nakagawa, Masao, Maeda, Michiyuki, Bamford, Richard N., Waldmann, Thomas A.“…In this study, we investigated the therapeutic efficacy of the single agents and combinations of these agents in a murine model of human ATL, the MT-1 model. Single and double agents inhibited tumor growth as monitored by tumor size (P < .05), and prolonged survival of leukemia-bearing mice (P < .05) compared with the control group. …”
Publicado 2014
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47por Yang, Dong-Lei, Zhang, Guiping, Wang, Lili, Li, Jingwen, Xu, Dachao, Di, Cuiru, Tang, Kai, Yang, Lan, Zeng, Liang, Miki, Daisuke, Duan, Cheng-Guo, Zhang, Huiming, Zhu, Jian-Kang“…Comprehensive genetic analyses using single and high order mutants of CLSY family proteins revealed their roles as double agents in the balance between methylation and demethylation reactions. …”
Publicado 2018
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48por Arshad, Saeed, Wei, Mengli, Ali, Qurban, Mustafa, Ghulam, Ma, Zhengqiang, Yan, Yuanxin“…Colchicine, nitrous oxide, oryzalin, and amiprophosmethyl are common chromosome-doubling agents that aid in developing viable diploids (2n) from sterile haploids (n). …”
Publicado 2023
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49por Zhang, Ning, Melo, Mary Anne S., Antonucci, Joseph M., Lin, Nancy J., Lin-Gibson, Sheng, Bai, Yuxing, Xu, Hockin H.K.“…RMGI with triple agents (MPC + DMAHDM + NAg) had much stronger antibacterial property than using a single agent or double agents (p < 0.05). Biofilm CFU on RMGI with triple agents was reduced by more than 3 orders of magnitude, compared to commercial control. …”
Publicado 2016
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50por Taghvaei, Fatemeh, Rastin, Sepideh Jafarzadeh, Milani, Attabak Toofani, Khameneh, Zakieh Rostamzadeh, Hamini, Forough, Rasouli, Mohammad Aziz, Asghari, Keivan, Rekabi Shishavan, Amir Mohammad, Ebrahimifar, Meysam, Rashidi, Siamak“…Bcl-2 gene expression ratios were decreased in double agents treated cells versus monotherapies. Following treatment of KYSE-30 cells with carboplatin and EGCG in double combinations, lactate levels were significantly decreased compared with the untreated cells and single treatments (P < 0.05). …”
Publicado 2021
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51por Zhao, Lina, Zhou, Yongchun, Pan, Haitao, Yin, Yutian, Chai, Guangjin, Mu, Yunfeng, Xiao, Feng, Lin, Steven H., Shi, Mei“…Methods: This study included 184 I-III elderly ESCC patients aged ≥70 years treated by oral single agent CCRT (sCCRT) or double agents CCRT (dCCRT) or RT alone at a single institution in China. …”
Publicado 2017
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52por Rosenblatt, Joel, Reitzel, Ruth, Vargas-Cruz, Nylev, Chaftari, Anne-Marie, Hachem, Ray Y, Raad, Issam“…Control catheters grew >10(4) CFU/segment. Single agent or double agents combinations were only partially effective in preventing colonization by all three pathogens. …”
Publicado 2017
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53por Elliott-Sale, Kirsty J., McNulty, Kelly L., Ansdell, Paul, Goodall, Stuart, Hicks, Kirsty M., Thomas, Kevin, Swinton, Paul A., Dolan, Eimear“…BACKGROUND: Oral contraceptive pills (OCPs) are double agents, which downregulate endogenous concentrations of oestradiol and progesterone whilst simultaneously providing daily supplementation of exogenous oestrogen and progestin during the OCP-taking days. …”
Publicado 2020
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