“…Scaffolding errors and incorrect repeat disambiguation during de novo assembly can result in large scale misassemblies in draft genomes. Nextera mate pair sequencing data provide additional information to resolve assembly ambiguities during scaffolding. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, we review the known physiological and immunological changes and genetic risk factors, identify candidates for further studies and integrate the information into a draft network for exploration on a systems level. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The term “biosimilar” refers to a biologic product that is developed to be highly similar, as opposed to identical, to a licensed biologic product (the reference or innovator product), such that, per US Food and Drug administration draft guidelines, “no clinically meaningful differences [exist] between the biological product and the reference product in terms of safety, purity, and potency.” …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Remarkable properties include the ability to grow on thiocyanate as the sole energy, sulfur and nitrogen source, and the capability of growth at salinities of up to 4.3 M total Na(+). This draft genome sequence consists of 61 scaffolds comprising 2,765,337 bp, and contains 2616 protein-coding and 61 RNA-coding genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is capable of complete denitrification under anaerobic conditions. The draft genome sequence consists of 3,746,647 bp in 3 scaffolds, containing 3558 protein-coding and 121 RNA genes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Subsequently, specialists from different disciplines were invited to discuss and draft protocols. RESULTS: Finalized triage tables summarizing the classification methods and required protocols in the field were designed after several meetings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS AND RESULTS: A 202-Mb draft genome assembly was generated from P. obducens using Illumina technology and mined to identify 13,483 SSR motifs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We report here draft whole genome sequences of three novel strains of Photorhabdus luminescens of 5.2–5.3 Mbps in size, and with a G + C content of 42.5% (each). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Genomic DNA of the MTB PR08 strain was extracted and subjected to whole genome sequencing using MiSeq (Illumina, CA,USA). The draft genome size of MTB PR08 strain is 4,292,364 bp with a G + C content of 65.2%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The recent completion of the draft genome sequence of a domestic pig and the development of next-generation sequencing technology during the past decade have created unprecedented possibilities to address these questions in great detail. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Advances in these technologies in the last five years have meant not only a reduction in the cost of whole genome sequencing, but also a substantial increase in the quality of the data, having moved from obtaining a draft genome sequence comprised of several hundred short contigs, sometimes of doubtful reliability, to the possibility of obtaining an almost complete and accurate chromosome sequence in a single contig, allowing a detailed study of gene clusters and the design of strategies for refactoring and full gene cluster synthesis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, the genome of U. oxytropis was firstly sequenced and assembled into a 70.05 megabases (Mb) draft genome, which encoded 11,057 protein-coding genes, and 54% of them were similar to current publicly available sequences. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The US Food and Drug Administration (FDA) has recently issued draft guidance on how it intends to regulate laboratory-developed tests, including genetic tests. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we present the high-quality draft genome of Flammeovirga sp. SJP92, together with its phenotypic characteristics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both assembled Hydrogenophaga draft genomes are missing a majority of the genetic components associated in the biosynthetic pathway of pABA and biotin. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It has a multiple range of hosts among amoeba and is characterized by a typical replication cycle of Chlamydiae with a particularity, recently shown in some chlamydia, which is the absence of inclusion vacuoles in the V. vermiformis host, adding by this a new member of Chlamydiae undergoing developmental cycle changes in the newly adapted host V. vermiformis. Draft genome sequencing revealed a chromosome of 2.86 Mb consisting of four contigs and a plasmid of 92 Kb.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Using high-throughput human-yeast genetic interaction screens, a first draft of disease interactome was obtained. This was achieved by first searching for candidate human disease genes that confer toxicity in yeast, and second, identifying modulators of toxicity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…DATA DESCRIPTION: We report a high-depth sequencing and de novo assembly of N. glauca full genome and analysis of genome elements with bacterial origin. The draft genome assembly is 3.2 Gb, with N50 size of 31.1 kbp. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Pine wilt disease, caused by the nematode Bursaphelenchus xylophilus, is one of the most devastating conifer diseases decimating several species of pine trees on a global scale. Here, we report the draft genome of Raoultella ornithinolytica MG, which is isolated from mountain-cultivated ginseng plant as an bacterial endophyte and shows nematicidal activity against B. xylophilus. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Based on the results a draft guideline in confidentiality in clinical setting was prepared and finalized in focus groups discussions.…”
Enlace del recurso
Enlace del recurso