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2021por Kelly, Andrew D., Kroeger, Heike, Yamazaki, Jumpei, Taby, Rodolphe, Neumann, Frank, Yu, Sijia, Lee, Justin T., Patel, Bela, Li, Yuesheng, He, Rong, Liang, Shoudan, Lu, Yue, Cesaroni, Matteo, Pierce, Sherry A., Kornblau, Steven M., Bueso-Ramos, Carlos E., Ravandi, Farhad, Kantarjian, Hagop M., Jelinek, Jaroslav, Issa, Jean-Pierre J.“…Expanded genome-wide digital restriction enzyme analysis of methylation (DREAM) data revealed a CGI methylator phenotype independent of IDH1/2 mutations we term AML-CIMP (A-CIMP(+)). …”
Publicado 2017
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2022por Mashl, R. Jay, Scott, Adam D., Huang, Kuan-lin, Wyczalkowski, Matthew A., Yoon, Christopher J., Niu, Beifang, DeNardo, Erin, Yellapantula, Venkata D., Handsaker, Robert E., Chen, Ken, Koboldt, Daniel C., Ye, Kai, Fenyö, David, Raphael, Benjamin J., Wendl, Michael C., Ding, Li“…GenomeVIP has been used for genomic analysis in large-data projects such as the TCGA PanCanAtlas and in other projects, such as the ICGC Pilots, CPTAC, ICGC-TCGA DREAM Challenges, and the 1000 Genomes SV Project. …”
Publicado 2017
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2023“…For most parts of the world, up-to-date digital elevation products with a resolution of less than 10 meters are a distant dream and, if available, those datasets have to be matched to the road network through an error-prone process. …”
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2024por Alfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu, Mahler, Stephen M.“…Therefore, increasing the selectivity of anti-cancer agents has the potential to dramatically enhance drug efficacy and reduce toxicity. EnGeneIC Dream Vectors (EDV) are antibody-targeted nanocells which can be loaded with cytotoxic drugs and delivered to specific cancer cells via bispecific antibodies (BsAbs) which target the EDV and a cancer cell-specific receptor, simultaneously. …”
Publicado 2017
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2025por Hall, Travis, Lie, Donald Y. C., Nguyen, Tam Q., Mayeda, Jill C., Lie, Paul E., Lopez, Jerry, Banister, Ron E.“…It has been the dream of many scientists and engineers to realize a non-contact remote sensing system that can perform continuous, accurate and long-term monitoring of human vital signs as we have seen in many Sci-Fi movies. …”
Publicado 2017
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2026“…The most frequent reasons that affected this choice were “humanitarian reasons and a wish to provide help to others” as well as “childhood dream,” “positive community appraisal of doctors,” and “ready availability of work for physicians.” …”
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2027“…Overall, the road ahead to clinical routine may still be rocky but the first successful long-term patients and progress in pre-clinical research provide encouraging evidence that deliberately inducing tolerance through hematopoietic chimerism might eventually make it from dream to reality.…”
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2028“…Any technology that can to facilitate collection, storage, process and retrieve information for health staff it can also have a positive impact in improving EBM. In general, EBM is a dream without the use of technologies and policymakers should seriously plan to use more IT.…”
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2029por Ripamonti, Ugo“…The induction of tissue formation, and the allied disciplines of tissue engineering and regenerative medicine, have flooded the twenty-first century tissue biology scenario and morphed into high expectations of a fulfilling regenerative dream of molecularly generated tissues and organs in assembling human tissue factories. …”
Publicado 2018
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2030“…To show its effectiveness we evaluate our method on a dataset from the DREAM 9 challenge. RESULTS: The results are encouraging and demonstrate the benefit of our approach to distinguish patient groups with different response to treatment. …”
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2031“…In keeping with China’s President Xi Jinping’s “Chinese Dream,” China has set a goal of becoming a world-class innovator by 2050. …”
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2032“…OBJECTIVE: Rapid eye movement sleep behavior disorder (RBD) is characterized by dream enactment and loss of muscle atonia during rapid eye movement sleep. …”
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2033por Melkevik, Ole, Clausen, Thomas, Pedersen, Jacob, Garde, Anne Helene, Holtermann, Andreas, Rugulies, Reiner“…METHODS: A sample of 6572 Danish female health care workers responding to a questionnaire about health and working conditions were followed up in a national register of social transfer payments (DREAM) for 550 days. We estimated the risk for LTSA of four weeks or more, associated with depressive symptoms and number of musculoskeletal pain locations using a Cox proportional hazards model allowing multiple observations per individual. …”
Publicado 2018
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2034por Gabryelska, A., Roguski, A., Simpson, G., Maschauer, E. L., Morrison, I., Riha, Renata L.“…OBJECTIVES: Rapid eye movement behaviour disorder (RBD) is a parasomnia in which there is loss of muscle atonia during rapid eye movement (REM) sleep, resulting in dream enactment. The aims of this study were to determine the prevalence of obstructive sleep apnoea (OSA) in RBD patients and determine whether continuous positive airway pressure (CPAP) therapy improved RBD symptoms in patients with concomitant RBD and OSA. …”
Publicado 2017
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2035por Jay, Kenneth, Thorsen, Sannie Vester, Sundstrup, Emil, Aiguadé, Ramon, Casaña, Jose, Calatayud, Joaquin, Andersen, Lars Louis“…Long-term sickness absence data were obtained from the Danish Register for Evaluation and Marginalization (DREAM). Time-to-event analyses (cox regression) controlled for various confounders estimated the association between fear avoidance beliefs (very low, low, moderate [reference category], high, and very high) at baseline and long-term sickness absence (LTSA; ≥6 consecutive weeks) during a 2-year follow-up. …”
Publicado 2018
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2036por Dubé, Karine, Gianella, Sara, Concha-Garcia, Susan, Little, Susan J, Kaytes, Andy, Taylor, Jeff, Mathur, Kushagra, Javadi, Sogol, Nathan, Anshula, Patel, Hursch, Luter, Stuart, Philpott-Jones, Sean, Brown, Brandon, Smith, Davey“…We must honor the lives of PLWHIV whose involvement in research can provide the knowledge needed to achieve the dream of making HIV infection curable.…”
Publicado 2018
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2037por Jalal, Baland“…Hallucinatory experiences triggered by serotonin—serotonergic (“pseudo”) hallucinations, induced by hallucinogenic drugs—tend to be “dream-like” with the experiencer having insight (“meta-awareness”) that he is hallucinating, unlike dopaminergic (“psychotic” and “life-like”) hallucinations where such insight is lost. …”
Publicado 2018
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2038por Darracq, Matthieu, Funk, Chadd M., Polyakov, Daniel, Riedner, Brady, Gosseries, Olivia, Nieminen, Jaakko O., Bonhomme, Vincent, Brichant, Jean-Francois, Boly, Melanie, Laureys, Steven, Tononi, Giulio, Sanders, Robert D.“…Conscious experience may be absent (unconsciousness) or take the form of dreaming, a state in which sensory stimuli are not incorporated into conscious experience (disconnected consciousness). …”
Publicado 2018
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2039“…CONCLUSIONS: We evaluated these approaches on simulated data for a repressilator, time-course data from past DREAM challenges, and a HeLa cell cycle dataset to show that they can produce accurate networks subject to the dynamics and assumptions of the time-lagged Ordered Lasso regression. …”
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2040por Kueffner, Robert, Zach, Neta, Bronfeld, Maya, Norel, Raquel, Atassi, Nazem, Balagurusamy, Venkat, Di Camillo, Barbara, Chio, Adriano, Cudkowicz, Merit, Dillenberger, Donna, Garcia-Garcia, Javier, Hardiman, Orla, Hoff, Bruce, Knight, Joshua, Leitner, Melanie L., Li, Guang, Mangravite, Lara, Norman, Thea, Wang, Liuxia, Xiao, Jinfeng, Fang, Wen-Chieh, Peng, Jian, Yang, Chen, Chang, Huan-Jui, Stolovitzky, Gustavo“…In this study we explored stratification through a crowdsourcing approach, the DREAM Prize4Life ALS Stratification Challenge. Using data from >10,000 patients from ALS clinical trials and 1479 patients from community-based patient registers, more than 30 teams developed new approaches for machine learning and clustering, outperforming the best current predictions of disease outcome. …”
Publicado 2019
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