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  1. 9801
    “…Following transmission, the virus population becomes more diverse because of recombination and acquired mutations through genetic drift and selection. Viral intrahost genetic diversity remains a major obstacle to the cure of HIV; however, the association between intrahost diversity and disease progression markers has not been investigated in large and diverse cohorts for which the majority of the genome has been deep-sequenced. …”
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    Deep-sequencing of viral genomes from a large and diverse cohort of treatment-naive HIV-infected persons shows associations between intrahost genetic diversity and viral load
  2. 9802
    por Sukhonos, Daniil
    Publicado 2020
    “…To satisfy these requirements, an in-vacuum drift detector based on ultralight 5m long and 2cm diameter straw tubes was proposed. …”
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    Spectrometer Straw Tracker design studies for the SHiP experiment
  3. 9803
    “…The stability of the system, when operated in EI, has been verified, and drifts leading to mask misalignment of less than 1 [Formula: see text] m have been measured over a period of 54 h. …”
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    PEPI Lab: a flexible compact multi-modal setup for X-ray phase-contrast and spectral imaging
  4. 9804
    “…Extrapolating from the observed upward drift in MIC values, the multi-step model projected ≥ 5% resistance to ceftriaxone could be reached by 2030, based on treatment pressure alone. …”
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    Projecting the development of antimicrobial resistance in Neisseria gonorrhoeae from antimicrobial surveillance data: a mathematical modelling study
  5. 9805
    “…In our model, increasing extrinsic mortality favors evolved aging by making up free space, thereby decreasing competition and increasing drift, even when selection is stabilizing and the level of aging is set by mutation-selection balance. …”
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    Directional selection coupled with kin selection favors the establishment of senescence
  6. 9806
    por Brurberg, K G, Graff, B A, Rofstad, E K
    Publicado 2003
    “…However, potential pitfalls were identified, and reliable pO(2) measurements require that precautions are taken to avoid these pitfalls, that is, erroneous pO(2) readings caused by tissue trauma induced by the probe, probe movements induced by reflex actions of the host mouse and occasional probe drift. Significant fluctuations in pO(2) were detected in the majority of the 70 tumour regions subjected to measurement. …”
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    Temporal heterogeneity in oxygen tension in human melanoma xenografts
  7. 9807
    “…CONCLUSIONS: The variation found at group and subgroup levels may reflect a combination of historical processes of migration/selection and adaptive factors to diverse agricultural environments that, together with genetic drift, have resulted in extensive genetic variation but limited population structure. …”
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    Analysis of the genetic diversity and structure across a wide range of germplasm reveals prominent gene flow in apple at the European level
  8. 9808
    “…BACKGROUND: Domestication and artificial selection have resulted in strong genetic drift, relaxation of purifying selection and accumulation of deleterious mutations. …”
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    A reverse genetic approach identifies an ancestral frameshift mutation in RP1 causing recessive progressive retinal degeneration in European cattle breeds
  9. 9809
    “…However, the trending ability was improved by auto-calibration, possibly by correcting a drift over a longer time period.…”
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    The value of arterial pressure waveform cardiac output measurements in the radial and femoral artery in major cardiac surgery patients
  10. 9810
    “…India displays a high level of endogamy due to its strict social boundaries, and high genetic drift as a result of long-term isolation which, together with a very complex history, makes the genetic study of Indian populations challenging. …”
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    A genetic chronology for the Indian Subcontinent points to heavily sex-biased dispersals
  11. 9811
    “…In the absence of significant natural, genetic drift might have caused differential pvmdr1 haplotype frequencies at different geographic sites in Mesoamerica. …”
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    Genetic diversity and natural selection of Plasmodium vivax multi-drug resistant gene (pvmdr1) in Mesoamerica
  12. 9812
    “…BACKGROUND: Deleterious genetic variation can increase in frequency as a result of mutations, genetic drift, and genetic hitchhiking. Although individual effects are often small, the cumulative effect of deleterious genetic variation can impact population fitness substantially. …”
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    A survey of functional genomic variation in domesticated chickens
  13. 9813
    “…Twenty-three people with a good working knowledge of NPT reviewed the items for theoretical drift. Items that displayed a poor alignment with NPT sub-constructs were removed (n = 8) and others revised or combined (n = 6). …”
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    Improving the normalization of complex interventions: part 1 - development of the NoMAD instrument for assessing implementation work based on normalization process theory (NPT)
  14. 9814
    “…It remains unclear how evolutionary forces, such as natural selection and random genetic drift, have affected neuropeptide genes among human populations. …”
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    Selected neuropeptide genes show genetic differentiation between Africans and non-Africans
  15. 9815
    “…Furthermore, unlike RT-PCR tests, immunoassays that target viral proteins and/or early host responses are less susceptible to sequence erosion due to viral genetic drift. Although virus is shed into the bloodstream from infected cells, the wide dynamic range of proteins in blood plasma makes this a difficult sample matrix for the detection of low-abundant viral proteins. …”
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    Early detection of Ebola virus proteins in peripheral blood mononuclear cells from infected mice
  16. 9816
    “…CONCLUSIONS: The circulation of drifted A(H3N2) strains during the 2014–2015 season was related to the high hospitalisation rate due to the mismatch with the vaccine strains. …”
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    Molecular influenza surveillance at a tertiary university hospital during four consecutive seasons (2012–2016) in Catalonia, Spain
  17. 9817
    “…The assembly of larval bacteria was overall governed by neutral processes (dispersal among individuals and ecological drift) at all the stages, but bacterioplankton also had certain contribution during three sub-stages of zoea, when larval and water bacterial communities were most associated. …”
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    Fine-scale succession patterns and assembly mechanisms of bacterial community of Litopenaeus vannamei larvae across the developmental cycle
  18. 9818
    “…While the contribution of some mainland breeds to the genetic diversity pool seems important, some island and fragmented mainland breeds suffer from a severe decline of population size and loss of alleles due to genetic drift. Conservation programs that are a compromise between what is feasible and what is desirable should focus not only on the still highly diverse mainland breeds but also promote and explore the conservation possibilities for island breeds.…”
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    Genomic diversity and population structure of the indigenous Greek and Cypriot cattle populations
  19. 9819
    “…Furthermore, our findings support the hypothesis that an ancient demographic decline affecting the chimpanzee populations – like that ascribed to a viral epidemic – exerted a substantial effect on the molecular diversity of their MHC genes, albeit not more pronounced than that experienced by HLA genes in human populations that underwent rapid genetic drift during humans’ peopling history. We thus propose a model where chimpanzees’ MHC genes regenerated molecular variation through recombination/gene conversion and/or balancing selection after the selective sweep.…”
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    Similar patterns of genetic diversity and linkage disequilibrium in Western chimpanzees (Pan troglodytes verus) and humans indicate highly conserved mechanisms of MHC molecular evolution
  20. 9820
    “…Because of its ability to evade immune surveillance through rapid antigenic drift and antigenic shift, broad-spectrum vaccines seem increasingly important. …”
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    Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus
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