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2521por Nonet, Michael“…The first generation of C. elegans GAL4 drivers for bipartite expression function less well than C. elegans tet ON/OFF, QF and LexA drivers. …”
Publicado 2021
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2522“…Consequently, gene duplication and gene fusion events are frequently observed in human malignancies and many of the products of these events are pathogenic, representing significant drivers of tumourigenesis and cancer evolution. In certain subsets of cancers duplicated and fused genes appear to be essential for initiation of tumour formation, and some even have the capability of transforming normal cells, highlighting the importance of understanding the events that result in their formation. …”
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2524por Espinoza-Morriberón, D., Echevin, V., Gutiérrez, D., Tam, J., Graco, M., Ledesma, J., Colas, F.“…Deoxygenation is a major threat to the coastal ocean health as it impacts marine life and key biogeochemical cycles. Understanding its drivers is crucial in the thriving and highly exploited Peru upwelling system, where naturally low-oxygenated subsurface waters form the so-called oxygen minimum zone (OMZ), and a slight vertical shift in its upper limit may have a huge impact. …”
Publicado 2021
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2525“…However, research has indicated that drivers may not efficiently deal with dynamically changing system configurations. …”
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2527
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2528por Agha, Sohail, Chine, Adaobi, Lalika, Mathias, Pandey, Samikshya, Seth, Aparna, Wiyeh, Alison, Seng, Alyssa, Rao, Nandan, Badshah, Akhtar“…This study applied a behavioral lens to understand drivers of COVID-19 vaccination uptake among healthcare workers (HCWs) in Nigeria. …”
Publicado 2021
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2529por Hale, Vanessa L.“…Kamada, et al., Cell 167:1339–1353.e21, 2016, https://doi.org/10.1016/j.cell.2016.10.043) have provided a foundation for studying drivers of gut microbial structure and change across host species in the context of evolution and disease risk.…”
Publicado 2021
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2530“…This study aims to develop a narrative to enable the understanding of the key drivers involved in its evolution and implications for future national patient safety policy development. …”
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2531“…To effectively inform public health responses, policy and strategy to deal with the current wave and prepare for further waves, we discuss the drivers and challenges of control for this current wave and future waves, and offer practical recommendations. …”
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2532por Vanbaelen, Thibaut, Van Dijck, Christophe, De Baetselier, Irith, Florence, Eric, Reyniers, Thijs, Vuylsteke, Bea, Jacobs, Bart KM, Kenyon, ChrisEnlace del recurso
Publicado 2021
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2533por Ávila, Mario I., Vajda, Élodie A., Gutiérrez, Eileen Jeffrey, Gibson, Daragh A., Renteria, Mariela Mosquera, Presley, Nicholas, O’Reilly, Daniel, Burton, Timothy A., Tatarsky, Allison, Lobo, Neil F.“…Government-led entomological surveillance using an entomological surveillance planning tool (ESPT) sought to answer programmatically-relevant questions that would enhance the understanding of both local entomological drivers of transmission and gaps in protection that result in persisting malaria transmission to guide local vector control decision-making. …”
Publicado 2021
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2534por Jung, Anne-Sophie, Haldane, Victoria, Neill, Rachel, Wu, Shishi, Jamieson, Margaret, Verma, Monica, Tan, Melisa, De Foo, Chuan, Abdalla, Salma M, Shrestha, Pami, Chua, Alvin Qijia, Bristol, Nellie, Singh, Sudhvir, Bartos, Michael, Mabuchi, Shunsuke, Bonk, Mathias, McNab, Christine, Werner, George K, Panjabi, Raj, Nordström, Anders, Legido-Quigley, HelenaEnlace del recurso
Publicado 2021
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2535por Varghese, Leila N., Carreño-Tarragona, Gonzalo, Levy, Gabriel, Gutiérrez-López de Ocáriz, Xabier, Rapado, Inmaculada, Martínez-López, Joaquín, Ayala, Rosa, Constantinescu, Stefan N.Enlace del recurso
Publicado 2021
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2536“…One of the key concepts employed in cancer driver gene identification is that of mutual exclusivity (ME); a driver mutation is less likely to occur in case of an earlier mutation that has common functionality in the same molecular pathway. …”
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2537por Chaudhari, Narendrakumar M., Overholt, Will A., Figueroa-Gonzalez, Perla Abigail, Taubert, Martin, Bornemann, Till L. V., Probst, Alexander J., Hölzer, Martin, Marz, Manja, Küsel, Kirsten“…Patescibacteria are predicted to have minimal biosynthetic and metabolic pathways, which hinders understanding of how their populations differentiate in response to environmental drivers or host organisms. Their mechanisms employed to cope with oxidative stress are largely unknown. …”
Publicado 2021
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2538“…These changes may be particularly challenging for drivers, as the population of truck drivers skews much older than that of other occupations. …”
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2539por Xiao, Jianyong, Xie, Binggeng, Zhou, Kaichun, Shi, Shana, Li, Junhan, Yang, Mingxia, Liu, ChangChang“…Detailed spatiotemporally mapping of soil erosion was used to determine the connections between soil erosion and potential drivers, which have important implications for vegetation restoration and the optimization of land use planning.…”
Publicado 2021
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2540“…In this review, we present emerging evidence that implicates the activated endothelium as a driver of atherosclerosis by directing site-specificity of plaque formation and by promoting plaque development through intracellular processes, which regulate endothelial cell proliferation and turnover, metabolism, permeability, and plasticity. …”
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