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3581por Cluver, Lucie Dale, Orkin, Frederick Mark, Meinck, Franziska, Boyes, Mark Edward, Sherr, Lorraine“…Measures included 1) potential structural drivers of HIV infection such as poverty and community violence; 2) HIV risk behaviours; 3) hypothesized psychosocial mediating factors; and 4) types of social protection involving cash and care. …”
Publicado 2016
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3582por Raghavan, Ram K., Hanlon, Cathleen A., Goodin, Douglas G., Davis, Rolan, Moore, Michael, Moore, Susan, Anderson, Gary A.“…In this study we evaluated the spatial and spatio-temporal patterns of infection status among striped skunk cases submitted for rabies testing in the North Central Plains of US in a Bayesian hierarchical framework, and also evaluated potential eco-climatological drivers of such patterns. Two Bayesian hierarchical models were fitted to point-referenced striped skunk rabies cases [n = 656 (negative), and n = 310 (positive)] received at a leading rabies diagnostic facility between the years 2007–2013. …”
Publicado 2016
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3583“…CONCLUSIONS: Several specific factors appear to underlie divergent statin therapy in women vs. men. Identifying such drivers may facilitate programmatic interventions and stimulate further research to overcome sex differences in applying proven interventions for cardiovascular risk reduction.…”
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3584Identification of cancer-driver genes in focal genomic alterations from whole genome sequencing data“…Several methods for identifying cancer-driver genes from multiple cancer patients have been developed for single nucleotide polymorphism (SNP) arrays. …”
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3585por Lerner, Lorena, Tao, Julie, Liu, Qing, Nicoletti, Richard, Feng, Bin, Krieger, Brian, Mazsa, Elizabeth, Siddiquee, Zakir, Wang, Ruoji, Huang, Lucia, Shen, Luhua, Lin, Jie, Vigano, Antonio, Chiu, M. Isabel, Weng, Zhigang, Winston, William, Weiler, Solly, Gyuris, Jeno“…The purpose of this work was the identification of key drivers of cancer cachexia that could provide a potential point of intervention for the treatment and/or prevention of this syndrome. …”
Publicado 2015
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3586por Fujimoto, Akihiro, Okada, Yukinori, Boroevich, Keith A., Tsunoda, Tatsuhiko, Taniguchi, Hiroaki, Nakagawa, Hidewaki“…Our study suggests that systematic analysis of mutation distribution in the tertiary protein structure can help identify cancer driver genes.…”
Publicado 2016
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3587“…However, it remains a challenge to delineate the key cancer driver genes from the regions encoding a large number of genes. …”
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3588por Cocchiaro, Pasquale, Fox, Christopher, Tregidgo, Nicholas W., Howarth, Rachel, Wood, Katrina M., Situmorang, Gerhard R., Pavone, Luigi M., Sheerin, Neil S., Moles, AnnaEnlace del recurso
Publicado 2016
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3589por Heydari, Seyed Taghi, Vossoughi, Mehrdad, Akbarzadeh, Armin, Lankarani, Kamran B., Sarikhani, Yaser, Javanmardi, Kazem, Akbary, Ali, Akbari, Maryam, Mahmoodi, Mojtaba, Shirazi, Mohammad Khabaz, Tabrizi, Reza“…CONCLUSION: Screening for alcohol and substance consumption among motorcycle drivers is an efficient way to identify drivers that are at a greater risk for road traffic accidents.…”
Publicado 2016
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3591por Rykunov, Dmitry, Beckmann, Noam D., Li, Hui, Uzilov, Andrew, Schadt, Eric E., Reva, Boris“…While DNA-based molecular profiling approaches have flourished over the past several years to transform our understanding of driver pathways across a broad range of tumors, a systematic characterization of key driver pathways based on RNA data has not been undertaken. …”
Publicado 2016
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3592Healthcare Programmes for Truck Drivers in Sub-Saharan Africa: A Systematic Review and Meta-Analysispor Lalla-Edward, Samanta Tresha, Fobosi, Siyabulela Christopher, Hankins, Catherine, Case, Kelsey, Venter, W. D. Francois, Gomez, Gabriela“…BACKGROUND: Truck drivers have unique health needs, and by virtue of their continuous travel, experience difficulty in accessing healthcare. …”
Publicado 2016
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3594por Ben-David, Uri, Ha, Gavin, Khadka, Prasidda, Jin, Xin, Wong, Bang, Franke, Lude, Golub, Todd R.“…Mining this resource, we find that most chromosomal aberrations accumulate late during breast tumorigenesis, and observe marked differences in CNA prevalence between mouse mammary tumours initiated with distinct drivers. Some aberrations are recurrent and unique to specific GEMMs, suggesting distinct driver-dependent routes to tumorigenesis. …”
Publicado 2016
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3595por Andersen, Signe Hald“…This article tests whether an alcohol treatment program for drunk drivers in Denmark increased the stability of their relationships with spouses or cohabiting partners. …”
Publicado 2016
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3596por Kouotou, Emmanuel Armand, Nansseu, Jobert Richie N., Kouawa, Michèle K., Zoung-Kanyi Bissek, Anne-CécileEnlace del recurso
Publicado 2016
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3597“…As a phased approach to initiating driving, graduated driver licensing restricts driving by young drivers with the aim of reducing crashes. …”
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3598por Hasegawa, Yoshikazu, Hoshino, Yoshikazu, Ibrahim, Abdelaziz E., Kato, Kanako, Daitoku, Yoko, Tanimoto, Yoko, Ikeda, Yoshihisa, Oishi, Hisashi, Takahashi, Satoru, Yoshiki, Atsushi, Yagami, Ken-ichi, Iseki, Hiroyoshi, Mizuno, Seiya, Sugiyama, Fumihiro“…In the present study, we generated novel cre driver mice for gene manipulation in pancreatic β cells. …”
Publicado 2016
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3599por Nabavi, Sheida“…RESULTS: To facilitate the identification of a short list of biologically meaningful genes as candidate drivers of anti-cancer drug resistance from an enormous amount of heterogeneous data, we employed statistical machine-learning techniques and integrated genomics datasets. …”
Publicado 2016
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3600por Chitsazzadeh, Vida, Coarfa, Cristian, Drummond, Jennifer A., Nguyen, Tri, Joseph, Aaron, Chilukuri, Suneel, Charpiot, Elizabeth, Adelmann, Charles H., Ching, Grace, Nguyen, Tran N., Nicholas, Courtney, Thomas, Valencia D., Migden, Michael, MacFarlane, Deborah, Thompson, Erika, Shen, Jianjun, Takata, Yoko, McNiece, Kayla, Polansky, Maxim A., Abbas, Hussein A., Rajapakshe, Kimal, Gower, Adam, Spira, Avrum, Covington, Kyle R., Xiao, Weimin, Gunaratne, Preethi, Pickering, Curtis, Frederick, Mitchell, Myers, Jeffrey N., Shen, Li, Yao, Hui, Su, Xiaoping, Rapini, Ronald P., Wheeler, David A., Hawk, Ernest T., Flores, Elsa R., Tsai, Kenneth Y.“…We identify the major transcriptional drivers of this progression sequence, showing that the key genomic changes in cuSCC development occur in the normal skin to AK transition. …”
Publicado 2016
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