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6001por Zhou, Zhixiong, Gu, Guojing, Luo, Yichen, Li, Wenjie, Li, Bowen, Zhao, Yu, Liu, Juan, Shuai, Xuehong, Wu, Li, Chen, Jixuan, Fan, Cailiang, Huang, Qingzhou, Han, Baoru, Wen, Jianjun, Jiao, Hanwei“…The DEGs related to immune pathway were identified by Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) functional enrichment analysis. …”
Publicado 2020
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6002“…The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of DEGs were screened by an online tool—Database for Annotation, Visualization, and Integration Discovery (DAVID). …”
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6003“…Gene Ontology (GO) enrichment analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, ingenuity pathway analysis (IPA), and protein-protein interaction (PPI) network analysis were then performed on DEGs. …”
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6004por Du, Yan-Yi, Chen, Zhi-Xin, Liu, Min-Ying, Liu, Qing-Ping, Lin, Chang-Song, Chu, Cong-Qiu, Xu, Qiang“…In this study, we detected 3,425 mRNAs differentially expressed between CD4(+) T cells of RA patients and those of healthy individuals using microarray raw data mining. Kyoto Encyclopedia of Genes and Genomes enrichment analysis revealed that transcriptional coactivator with PDZ-binding motif (TAZ) regulates a variety of biological processes including T-helper (Th)-17 cell development, and was thus selected for functional verification. …”
Publicado 2020
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6005por Wu, Fei, Zhi, Xinyue, Xu, Rong, Liang, Zhiyi, Wang, Fang, Li, Xiaoyu, Li, Yongmei, Sun, Bei“…Based on the results of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis, the predicted target mRNAs of the identified colostrum-specific microRNAs were involved in the regulation of distinct biological processes, such as signal transduction, positive regulation of GTPase activity, and protein phosphorylation. …”
Publicado 2020
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6006por Ma, Fan, Wang, Ziran, Qiang, Yawen, Xu, Liangfei, Ding, Pengsheng, Wang, Yangyan, Ma, Xiaoling“…RNA sequencing and Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Enrichment Analysis (GSEA) pathway analyses revealed the downstream signaling pathway targets of LukS-PV. …”
Publicado 2020
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6007por Fan, Feifei, Ping, Yu, Yang, Li, Duan, Xiaoran, Resegofetse Maimela, Nomathamsanqa, Li, Bingjie, Li, Xiangnan, Chen, Jing, Zhang, Kai, Wang, Liping, Liu, Shasha, Zhao, Xuan, Wang, Hongmin, Zhang, Yi“…We analysed the functions and pathways of 981 DE mRNAs using the Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. Based on the target DE mRNAs and DE lncRNAs of DE miRNAs, we established an lncRNA‐miRNA‐mRNA ceRNA network, comprising 37 DE lncRNAs, 22 DE miRNAs and 212 DE mRNAs. …”
Publicado 2020
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6008“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed using the online Database for Annotation, Visualization and Integrated Discovery (DAVID) tool. …”
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6009“…Co-regulated DEGs in at least two datasets were analyzed with the enrichment of Gene Ontology Biological Process (GO-BP), Kyoto Encyclopedia of Genes and Genomes (KEGG), protein-protein interaction (PPI) networks, interrelationships between miRNAs/transcriptional factors, and their target genes and drug-gene interactions. …”
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6010por Zhang, Yujie, Zhang, Xiaolin, Zhang, Xi, Cai, Yi, Cheng, Minghui, Yan, Chenghui, Han, Yaling“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGGs) pathway enrichment analyses were performed. …”
Publicado 2020
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6011“…Finally, the mechanism of ILK in EGFR-TKIs resistance was analyzed using Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO) and ingenuity pathway analysis (IPA). …”
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6012“…The enrichment functions of autophagy differential genes were analyzed by Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). The Kaplan-Meier method was applied to the survival curve analysis. …”
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6013“…The action target Gene Ontology (GO) biological processes and metabolic pathways in Kyoto Encyclopedia of Genes and Genomes (KEGG) of XXMD to treat CIS were enrichment analyzed with R software. …”
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6014por Wu, Bo, Jiang, Shanshan, Wang, Xinhui, Zhong, Sheng, Bi, Yiming, Yi, Dazhuang, Liu, Ge, Hu, Fangfei, Dou, Gaojing, Chen, Yong, Wu, Yi, Dong, Jiajun“…Enrichment functions, pathways and key genes were identified by carrying out GO (Gene Ontology), KEGG (Kyoto Encyclopedia of Genes and Genomes) analysis and PPI (Protein-Protein Interation) network analysis. …”
Publicado 2020
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6015“…Finally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were carried out. …”
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6016por Qu, Yan-Fu, Wu, Yan-Qing, Zhao, Yu-Tian, Lin, Long-Hui, Du, Yu, Li, Peng, Li, Hong, Ji, Xiang“…In both species the gut microbiota had functional roles in enhancing metabolism, genetic information processing and environmental information processing according to the Kyoto Encyclopedia of Genes and Genomes database. The potential to gain mass is greater in T. s. elegans than in C. reevesii, as revealed by the fact that the Firmicutes/Bacteroidetes ratio was lower in the former species. …”
Publicado 2020
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6017“…Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) and protein interaction analyses were performed, and differential protein expression was verified by western blotting and reverse transcription-quantitative PCR (RT-qPCR). …”
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6018por Lin, Jun, Liang, Ping, Huang, Qing, Jian, Chongdong, Huang, Jianmin, Tang, Xionglin, Li, Xuebin, Liao, Yanling, Huang, Xiaohua, Huang, Wenhua, Su, Li, Meng, Lanqing“…Enrichment of gene data was performed using Gene Ontology analysis and the Kyoto Encyclopedia of Genes and Genomes database. Hub genes were identified and networks were constructed using Cytoscape that were further verified by reverse transcription-quantitative PCR. …”
Publicado 2020
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6019por Zhang, Heng, Qin, Hong, Zhou, Chengen, Feng, Qiang, Yang, Yuan, Sui, Jinhui, Tang, Yucai“…Reverse transcription-quantitative PCR validation indicated that the alterations in expression of uroplakin 3B-like 1 (UPK3BL1), voltage-dependent calcium channel subunit α-2/δ-1 (CACNA2D1) and polo-like kinase 4 (PLK4) were consistent with the corresponding results of RNA-Seq, and that these genes were involved in both LPS-stimulation and SyrA-reversion processes. Kyoto Encyclopedia of Genes and Genomes analyses indicated that the DEGs in SyrA-reversed groups were involved in, amongst other pathways, ‘Autophagy-other’ and ‘Apoptosis-multiple species’. …”
Publicado 2020
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6020“…Differentially expressed genes (DEGs) induced in these conditions were identified and examined using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analysis. Cisplatin increased the expression of genes related to the p53 and FoxO pathways, such as Fas, p21/CDKN1A, and Bcl-2 binding component 3, but decreased the expression of insulin-like growth factor 1 (IGF1), as well as genes in the histone (Hist)1 and Hist2 clusters. …”
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