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7301“…Biological analysis using the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway on the identified miRNAs revealed their influence in GBM cancer. …”
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7302por Zhang, Fu-Kai, Zhang, Xiao-Xuan, Elsheikha, Hany M., He, Jun-Jun, Sheng, Zhao-An, Zheng, Wen-Bin, Ma, Jian-Gang, Huang, Wei-Yi, Guo, Ai-Jiang, Zhu, Xing-Quan“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed that transcriptional changes in the liver of infected buffaloes evolve over the course of infection. …”
Publicado 2017
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7303“…Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were then performed to explore their function. …”
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7304“…Subsequently, we constructed a network with the five miRNAs-target mRNAs; gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were utilized to recognize the functions and associated pathways. …”
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7305“…In addition, 10,402 unigenes were annotated in the Cluster of Orthologous Groups database, 12,088 unigenes were assigned to the Gene Ontology database and 12,269 unigenes were in the Kyoto Encyclopedia of Genes and Genome (KEGG) database. Exposure to beta-cypermethrin had significant effects on the transcriptome profile of H. axyridis adult. …”
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7306por Li, Ruixue, Chen, Dandan, Wang, Taichu, Wan, Yizhen, Li, Rongfang, Fang, Rongjun, Wang, Yuting, Hu, Fei, Zhou, Hong, Li, Long, Zhao, Weiguo“…Gene Ontology (GO) annotations and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that these target transcripts were implicated in a broad range of biological processes and various metabolic pathways. …”
Publicado 2017
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7307por Zhang, Shuai, Zhu, Dina, Li, Hong, Zhang, Haijing, Feng, Chengqiang, Zhang, Wensheng“…Analyses according to gene ontology and the Kyoto Encyclopedia of Genes and Genomes revealed that oral administration of GRg1 and GRb1 improved the learning performance of the SAMP8 mouse model from various aspects, such as nervous system development and mitogen-activated protein kinase signaling pathway. …”
Publicado 2017
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7308por Xia, Fan, Yao, Xiaorui, Tang, Waijiao, Xiao, Chunxin, Yang, Miaoting, Zhou, Benjie“…Based on the Kyoto Encyclopedia of Gene and Genomes pathway enrichment analysis, it is concluded that several pathways including those of microbial metabolism in diverse environments, fatty acid metabolism, peroxisome proliferator activated receptor signaling, and mitogen-activated protein kinase signaling are closely associated with the effects of Hugan Qingzhi-medicated serum in FFA-induced L02 hepatocyte injury. …”
Publicado 2017
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7309por Rosenberger, Albert, Sohns, Melanie, Friedrichs, Stefanie, Hung, Rayjean J., Fehringer, Gord, McLaughlin, John, Amos, Christopher I., Brennan, Paul, Risch, Angela, Brüske, Irene, Caporaso, Neil E., Landi, Maria Teresa, Christiani, David C., Wei, Yongyue, Bickeböller, Heike“…Overall, the information taken from 11,365 cases and 22,505 controls from within the TRICL/ILCCO consortia was used to investigate a total of 234 pathways from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. RESULTS: META-GSA reveals the systemic lupus erythematosus KEGG pathway hsa05322, driven by the gene region 6p21-22, as also implicated in lung cancer (p = 0.0306). …”
Publicado 2017
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7310por Zhang, Xiaoning, Gao, Fengxin, Fu, Jianbo, Zhang, Peng, Wang, Yuqing, Zeng, Xuhui“…In contrast, differentially expressed transcripts of mRNAs were highly enriched for protein metabolic process and RNA metabolic, spermatogenesis, sperm motility, cell cycle, chromatin organization, heterocycle and aromatic compound metabolic processes. Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis showed that the differentially expressed lncRNAs were involved in RNA transport, mRNA surveillance pathway, PI3K-Akt signaling pathway, AMPK signaling pathway, protein processing in endoplasmic reticulum. …”
Publicado 2017
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7311por Xu, Leifeng, Yang, Panpan, Feng, Yayan, Xu, Hua, Cao, Yuwei, Tang, Yuchao, Yuan, Suxia, Liu, Xinyan, Ming, Jun“…A total of 16,182 unigenes were identified as differentially expressed genes during tepal development. Using Kyoto Encyclopedia of Genes and Genomes pathway analysis, candidate genes involved in the anthocyanin biosynthetic pathway (61 unigenes), and chlorophyll metabolic pathway (106 unigenes) were identified. …”
Publicado 2017
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7312por Yang, Ze-Min, Chen, Long-Hui, Hong, Min, Chen, Ying-Yu, Yang, Xiao-Rong, Tang, Si-Meng, Yuan, Qian-Fa, Chen, Wei-Wen“…Target prediction showed that 97 T2DM candidate genes were potentially modulated by these seven miRNAs. Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed that 24 pathways were enriched for these genes, and the majority of these pathways were enriched for the targets of induced and repressed miRNAs, among which insulin, adipocytokine and T2DM pathways, and several cancer-associated pathways have been previously associated with T2DM. …”
Publicado 2017
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7313por Zhang, Lu, Xu, Bin, Wu, Tao, Yang, Yanfang, Fan, Lianxue, Wen, Muxuan, Sui, Jiaxin“…The reliability of the RNA-Seq was further confirmed by using real-time quantitative PCR. Kyoto Encyclopedia of Genes and Genomes enrichment analysis of the differentially expressed genes revealed ‘flavonoid biosynthesis’ was the only enriched pathway in the purple-leafed variety: In the pathway of phenylpropanoid metabolism, Bra017210, Bra039777, and Bra021637 were expressed at higher levels in the purple-leafed variety; among the early anthocyanin biosynthetic genes, Bra037747 transcripts were only detected in the purple-leafed variety but not in the green-leafed one; among the late anthocyanin biosynthetic genes, Bra027457, Bra013652, Bra019350, Bra003021, Bra035004, and Bra038445 were all up-regulated in purple-leafed variety; and genes encoding anthocyanin-related transcription factors, such as Bra016164, and genes encoding anthocyanin transportation, such as GST F12, were also identified as up-regulated ones in the purple-leafed variety. …”
Publicado 2017
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7314por Kirby, Marie K., Ramaker, Ryne C., Roberts, Brian S., Lasseigne, Brittany N., Gunther, David S., Burwell, Todd C., Davis, Nicholas S., Gulzar, Zulfiqar G., Absher, Devin M., Cooper, Sara J., Brooks, James D., Myers, Richard M.“…We overlaid the most significantly differentially methylated sites in the genome with transcription factor binding sites measured by the Encyclopedia of DNA Elements consortium. We used logistic regression and receiver operating characteristic curves to assess the performance of candidate diagnostic models. …”
Publicado 2017
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7315“…The predicted target genes were further analyzed by Gene Ontology term enrichment analysis, Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis and protein-protein interaction analysis. …”
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7316por Guo, Wuxia, Wu, Haidan, Zhang, Zhang, Yang, Chao, Hu, Ling, Shi, Xianggang, Jian, Shuguang, Shi, Suhua, Huang, Yelin“…Orthology annotations of Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Clusters of Orthologous Groups revealed overall similarities in the transcriptome profiles among the five species, whereas enrichment analysis identified remarkable genomic characteristics that are conserved across the four mangrove species but differ from their terrestrial relative. …”
Publicado 2017
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7317“…EDDY has been used in conjunction with the Cancer Therapeutics Response Portal (CTRP), a dataset with drug-response measurements for more than 400 small molecules, and RNAseq data of cell lines in the Cancer Cell Line Encyclopedia (CCLE) to find potential drug-mediator pairs. …”
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7318“…Next, the enriched Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were obtained using the online tool DAVID (http://david.abcc.ncifcrf.gov/). …”
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7319“…Differentially expressed miRNAs were profiled using miRNA array, verified by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and subjected to gene ontology (GO) term and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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7320“…The functional annotation and potential pathways of differentially expressed genes (DEGs) were further discovered by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. …”
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