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8201por Guo, Siyu, Tan, Yingying, Huang, Zhihong, Li, Yikui, Liu, Weiyu, Fan, Xiaotian, Zhang, Jingyuan, Stalin, Antony, Fu, Changgeng, Wu, Zhishan, Wang, Penglong, Zhou, Wei, Liu, Xinkui, Wu, Chao, Jia, Shanshan, Zhang, Jinyan, Duan, Xiaoxia, Wu, Jiarui“…Results: A total of 12 active components of DHI were obtained, and 158 common targets of component and disease were identified by systems pharmacology. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis results showed that DHI is closely related to the calcium signaling pathway in the treatment of AMI. …”
Publicado 2022
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8202“…Functional enrichment analyses, including Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) and gene set enrichment analysis were implemented to analyze the possible biological processes and signaling pathways of hub lncRNAs. …”
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8203“…Afterwards, the co-targets were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment. …”
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8204por Liu, Qiankun, Li, Pengtao, Cheng, Shuang, Zhao, Zilin, Liu, Yuling, Wei, Yangyang, Lu, Quanwei, Han, Jiangping, Cai, Xiaoyan, Zhou, Zhongli, Umer, Muhammad Jawad, Peng, Renhai, Zhang, Baohong, Liu, Fang“…Plant hormone signal transduction, phenylpropanoid biosynthesis, and MAPK signaling pathway were found to be enriched via Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. Twenty-two and nine salinity-responsive DEGs participated in plant hormone signaling and MAPK signaling in roots, before and after protoplast dissociation, respectively; six upregulated DEGs were involved in ABA signaling transduction, namely, Ga04G2111, Ga07G0142, Ga09G2061, Ga10G0262, Ga01G0063, and Ga08G1915 which indicates their potential functions on plants adapting to salt stress. …”
Publicado 2022
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8205por Huang, Jie, Wei, Shanshan, Jiang, Chuanhao, Xiao, Zijun, Liu, Jian, Peng, Weijun, Zhang, Bikui, Li, Wenqun“…Functional enrichment with Cluster of orthologous groups of proteins (COG) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses showed that the Dox mice displayed different clusters of cellular processes and metabolism from the Con mice. …”
Publicado 2022
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8206por Wu, Ji, Wang, Zhenhua, Xu, Shanling, Fu, Yang, Gao, Yi, Wu, Zuxiang, Yu, Yun, Yuan, Yougen, Zhou, Lin, Li, Ping“…METHODS: Network pharmacology was used to predict the potential targets and molecular mechanisms of EGCG in the treatment of septic cardiomyopathy, including the construction and analysis of protein-protein interaction (PPI) network, gene ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis and molecular docking. …”
Publicado 2022
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8207por Wang, Hufei, Luo, Kangjia, Guan, Zilong, Li, Zhi, Xiang, Jun, Ou, Suwen, Tao, Yangbao, Ran, Songlin, Ye, Jinhua, Ma, Tianyi, Qiao, Tianyu, Zhang, Zhiming, Jin, Yinghu, Song, Yanni, Huang, Rui“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis suggested that CCL22 was related to immune-related terms. …”
Publicado 2022
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8208“…Two types of analysis—Gene Ontology (GO) functional and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment—were accomplished by applying Database for Annotation, Visualization, and Integrated Discovery (DAVID) and Search Tool for the Retrieval of Interacting Genes database (STRING) online bioinformatics tools. …”
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8209“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to predict the biological and functional roles of these target genes. …”
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8210por Jiang, Xiulin, Tang, Lin, Yuan, Yixiao, Wang, Juan, Zhang, Dahang, Qian, Kebao, Cho, William C., Duan, Lincan“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were analyzed using DAVID and gene set enrichment analysis (GSEA) software. …”
Publicado 2022
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8211“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were performed on the DEGs. …”
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8212“…Public databases, including the Gene Expression Omnibus, Cancer Cell Line Encyclopedia, LinkedOmics, GeneMANIA, TISIDB, and Gene Set Cancer Analysis, were employed for relevant bioinformatic studies. …”
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8213por Yang, JinKe, Yang, Bo, Wang, Yong, Zhang, Ting, Hao, Yu, Cui, HuiMei, Zhao, DengShuai, Yuan, XingGuo, Chen, XueHui, Shen, ChaoChao, Yan, WenQian, Zheng, HaiXue, Zhang, KeShan, Liu, Xiangtao“…The biological function of the differentially expressed circRNAs was determined by protein interaction network, Gene Ontology (GO), and Kyoto Encyclopedia of Gene and Genome (KEGG) pathway enrichment. …”
Publicado 2022
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8214por Liu, Tingting, Li, Rui, Luo, Nanjian, Lou, Peng, Limesand, Sean W., Yang, You, Zhao, Yongju, Chen, Xiaochuan“…Lipid metabolism impairment, increased oxidative stress, and inflammation were observed by transcriptome analysis. Meanwhile, Kyoto Encyclopedia of Genes and Genomes (KEGG) annotation further demonstrated lipid peroxidation, antioxidant pathway, and pro-inflammatory response involved in the hepatic lipid dysregulation from LBW group. …”
Publicado 2022
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8215por Miao, Mingjun, Tan, Huaqiang, Liang, Le, Huang, Haitao, Chang, Wei, Zhang, Jianwei, Li, Ju, Tang, Yi, Li, Zhi, Lai, Yunsong, Yang, Liang, Li, Huanxiu“…Transcription factors (TF) prediction, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of DEGs were also performed. …”
Publicado 2022
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8216“…In total, 178 immune-related differentially expressed genes (DEGs) were identified. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that many cellular responses were enriched in the top 20 terms. …”
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8217“…Their biofunctions and related pathways were explored using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. …”
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8218“…Gene ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis showed that these SDE miRNAs were primarily involved in erythrocyte differentiation, lymphoid organ development, immune response, lipid metabolic process, the B cell receptor signaling pathway, the T cell receptor signaling pathway, and the PPAR signaling pathway. …”
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8219por Yin, Fanxing, Zhang, Hao, Guo, Panpan, Wu, Yihao, Zhao, Xinya, Li, Fangjun, Bian, Ce, Chen, Chen, Han, Yanshuo, Liu, Kun“…As indicated by Gene Ontology (GO) functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, these genes were mainly associated with extracellular matrix (ECM) and smooth muscle cells (SMCs). …”
Publicado 2022
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8220“…Then, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were utilized to analyze MD2-related signal pathways. …”
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