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8401por Li, Lihua, Yang, Kaibo, Li, Cong, Zhang, Han, Yu, Honghua, Chen, Kang, Yang, Xiaohong, Liu, Lei“…Using metabolomic analyses, we found 116 differentially expressed metabolites with a positive ion model and 168 differentially expressed metabolites with a negative ion model between the two groups. Kyoto Encyclopedia of Genes and Genomes annotation revealed six pathways with different levels between DR and diabetic controls, namely, cellular processes, environmental information processing, genetic information processing, human diseases, organismal systems and metabolism. …”
Publicado 2022
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8402por Xu, Zhongbao, Chen, Siying, Chen, Weihu, Zhou, Xiaolong, Yan, Feifei, Huang, Tao, Wang, Yaqin, Lu, Huangda, Zhao, Ayong“…RNA-seq found 93 differentially expressed genes (DEGs) in the short-photoperiod group, including 55 upregulated DEGs and 38 downregulated DEGs, distributed in 37 gene ontology categories. Kyoto Encyclopedia of Genes and Genomes-enriched signaling pathways revealed 5 pathways enriched in upregulated DEGs, including protein digestion and absorption, ECM-receptor interaction and regulation of lipolysis in adipocytes, and 4 pathways enriched in downregulated DEGs, such as fatty acid biosynthesis. …”
Publicado 2022
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8403“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs were performed using the database annotation, visualization and integrated discovery database. …”
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8404por Wang, Bei-Bei, Lai, Ying-Fang, Li, Fei-Fei, Jiao, Lu, Qiao, Qing-Xuan, Li, Shan-Yu, Xiang, Xiu-Juan, Liao, Huang, You, Min-Sheng, He, Wei-Yi“…During host transfer, the expression of PxMETTL14 was consistent with the change in m(6)A content, which implied that PxMETTL14 could respond to host plant defense effectively, and may regulate m(6)A content. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of the differentially expressed transcripts with changes in m(6)A levels revealed that the potential functions of m(6)A-related genes may be involved in steroid biosynthesis for larval performance and metabolic pathways for adult reproduction. …”
Publicado 2022
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8405por Bu, He, Cao, Ting, Li, Xuesong, Guo, Yuekun, Guo, Jiajia, Wang, Yuxin, Sun, Yunlong, Wang, Donghong“…METHODS: Gene expression, copy number (CN), and dependency score (DS) data were obtained from the Cancer Cell Line Encyclopedia (CCLE), and linear regression analyses were performed using R language. …”
Publicado 2022
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8406por Hong, Yongxing, Zhang, Lang, Liu, Xingting, Wu, Sile, Wen, Jian, Sun, Haodong, Tian, Kui, Jia, Xiaoxuan, Liao, Yuying, Suthikrai, Wanwipa, Tharasanit, Theerawat, Lu, Yangqing“…The assigned functions of the unigenes revealed that LST primarily influenced the mechanisms underlying catalytic activity and cellular processes. Kyoto Encyclopedia of Genes and Genomes enrichment analysis suggested that spermatogenesis-related pathways were significantly enriched, including ABC transporters, ribosome biogenesis in eukaryotes, and VEGF, cAMP, and ErbB signaling pathways.…”
Publicado 2022
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8407“…Functional enrichment analyses, including Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, Disease Ontology (DO), and Gene Set Enrichment Analysis (GSEA), were performed. …”
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8408por Ma, Yanyun, Wang, Chunxia, Shi, Mengqi, Li, Mingshan, Li, Lin, Che, Tuanjie, Qu, Jing“…The Gene Ontology functional enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses were conducted in order to define the nearest neighbouring genes of differentiated methylation sites. …”
Publicado 2022
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8409“…DEmRNAs were enriched in 521 Gene Ontology terms and 71 Kyoto Encyclopedia of Genes and Genomes terms which were mainly biological processes and metabolic pathways related to immune response and inflammatory response. …”
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8410por Janani, Balakarthikeyan, Vijayakumar, Mayakrishnan, Priya, Kannappan, Kim, Jin Hee, Geddawy, Ayman, Shahid, Mohammad, El-Bidawy, Mahmoud H., Al-Ghamdi, Sameer, Alsaidan, Mohammed, Abdelzaher, Mohammad Hassan, Mohideen, Abubucker Peer, Ramesh, Thiyagarajan“…Annotation of target proteins was performed using Gene Ontology (GO) database DAVID and signaling pathway enrichment analysis using the Kyoto Encyclopedia and Genome Database (KEGG). Survival and molecular docking analysis for the hub genes revealed three genes (PDGFRA, PTGS2, and MMP9) were involved in the overall survival of CRC patients, and the top three genes with the lowest binding energy include PDGFRA, MET, and MAPK1. …”
Publicado 2022
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8411por Wang, Shuying, Liang, Xiaoxing, Guo, Ruomi, Gong, Jiao, Zhong, Xiaolong, Liu, Yulin, Wang, Deqing, Hao, Yanmei, Hu, Bo“…The molecular functions included tubulin-binding, microtubule-binding, and DNA replication origin binding. The Kyoto Encyclopedia of Genes and Genomes signaling pathways related to the hub genes mainly included the cell cycle, human T-cell leukemia virus (type 1) infection, inflammatory bowel disease, and the intestinal immune network for immunoglobulin A production. …”
Publicado 2022
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8412“…Gene Ontology term analysis, Kyoto Encyclopedia of Genes and Genomes analysis, and gene set enrichment analysis were performed on PAQR5 to explain the enrichment pathways and functions. …”
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8413“…The majority of Kyoto Encyclopedia of Genes and Genomes (KEGG) were WNT, MAPK, and ERBB signaling pathways. …”
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8414por Tang, Bincheng, Xie, Guangjuan, Hu, Xinyue, Zhang, Xin, Hu, Shenqiang, Hu, Jiwei, Hu, Bo, Li, Liang, Wang, Jiwen“…Gene Ontology (GO) analysis showed that the DEPs were mainly enriched in transmembrane transport, extracellular matrix structural constituent, transferase activity, transferring acyl groups other than amino-acyl groups, transmembrane transporter activity, and integral component of membrane (P < 0.05). Kyoto Encyclopedia of Genes and Genomes (KEGG) functional enrichment analysis indicated that the DEPs were significantly enriched in apoptosis, tyrosine metabolism, glycerophospholipid metabolism, and sulfur metabolism pathways (P < 0.05). …”
Publicado 2022
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8415por Li, Rong, Zhang, Yanjiao, Xiang, Runqing, Lin, Aihe, Xia, Zongxiao, Long, Xiaomei, Guo, Shuang, Fan, Yuan, Chen, Zukun“…Then, gene ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, Venn diagram analysis of shared genes, and protein–protein interaction (PPI) network analysis were used to analyze the therapeutic effect of the MA on TPC-1 cells. …”
Publicado 2022
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8416“…The cluster Profiler package was used to perform Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis of upregulated and downregulated genes. …”
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8417por Zhang, Xiaoling, Yao, Wentao, Zhao, Wannian, Sun, Yingru, Wu, Zongkai, He, Weiliang, Ji, Yingxiao, Gao, Yaran, Niu, Xiaoli, Li, Litao, Wang, Hebo“…Then, the common 1231 DE-mRNAs, 32 DE-lncRNAs and 31 DE-circRNAs with opposite trends were identified. The Kyoto Encyclopedia of Genes and Genomes to identify the functional enrichment of 1231 DE-mRNAs were enriched in neurogenesis-related biological processes. …”
Publicado 2022
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8418“…“Gene ontology (GO)” and “Kyoto Encyclopedia of Genes and Genomes (KEGG)” data were analyzed by the “DAVID” software. …”
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8419por Ma, Rong, Shang, Fangzheng, Rong, Youjun, Pan, Jianfeng, Wang, Min, Niu, Shuran, Qi, Yunpeng, Li, Yanbo, Lv, Qi, Wang, Zhiying, Wang, Ruijun, Su, Rui, Liu, Zhihong, Zhao, Yanhong, Wang, Zhixin, Li, Jinquan, Zhang, Yanjun“…Finally, target genes were analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG), and it was found that they were mainly enriched in the Wnt signaling pathway and PI3K-Akt signaling pathway related to hair follicle development, indicating that lncRNA may interact with miRNA/mRNA to directly or indirectly regulate the expression of genes related to hair follicle development. …”
Publicado 2022
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8420“…According to data from the Kyoto Encyclopedia of Genes and Genomes database, DNAH9 and TNF are involved in the amyotrophic lateral sclerosis (ALS) pathway. …”
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