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9201“…In addition, the Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses for DEGs were performed. …”
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9202por Huang, Siqi, Zhang, Zheyu, Li, Wenqun, Kong, Fanhua, Yi, Pengji, Huang, Jianhua, Mao, Dan, Peng, Weijun, Zhang, Sifang“…Important ingredients, potential targets, and signaling pathways were determined through bioinformatics analysis, including protein–protein interaction (PPI), the Gene Ontology (GO), and the Kyoto Encyclopedia of Genes and Genomes (KEGG). Subsequently, molecular docking and cell experiments were performed to further verify the findings. …”
Publicado 2020
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9203“…Mutation data were analyzed and mapped using the maftools package in R software. Kyoto Encyclopedia of Genes and Genomes, Reactome and Gene Ontology analyses were performed using the clusterProfiler package in R software. …”
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9204por Partridge, E. Christopher, Chhetri, Surya B., Prokop, Jeremy W., Ramaker, Ryne C., Jansen, Camden S., Goh, Say-Tar, Mackiewicz, Mark, Newberry, Kimberly M., Brandsmeier, Laurel A., Meadows, Sarah K., Messer, C. Luke, Hardigan, Andrew A., Coppola, Candice J., Dean, Emma C., Jiang, Shan, Savic, Daniel, Mortazavi, Ali, Wold, Barbara J., Myers, Richard M., Mendenhall, Eric M.“…Here we present, as part of the ENCODE (Encyclopedia of DNA Elements) project, data and analyses from chromatin immunoprecipitation followed by high-throughput sequencing (ChIP–seq) experiments using the human HepG2 cell line for 208 chromatin-associated proteins (CAPs). …”
Publicado 2020
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9205por Gorkin, David U., Barozzi, Iros, Zhao, Yuan, Zhang, Yanxiao, Huang, Hui, Lee, Ah Young, Li, Bin, Chiou, Joshua, Wildberg, Andre, Ding, Bo, Zhang, Bo, Wang, Mengchi, Strattan, J. Seth, Davidson, Jean M., Qiu, Yunjiang, Afzal, Veena, Akiyama, Jennifer A., Plajzer-Frick, Ingrid, Novak, Catherine S., Kato, Momoe, Garvin, Tyler H., Pham, Quan T., Harrington, Anne N., Mannion, Brandon J., Lee, Elizabeth A., Fukuda-Yuzawa, Yoko, He, Yupeng, Preissl, Sebastian, Chee, Sora, Han, Jee Yun, Williams, Brian A., Trout, Diane, Amrhein, Henry, Yang, Hongbo, Cherry, J. Michael, Wang, Wei, Gaulton, Kyle, Ecker, Joseph R., Shen, Yin, Dickel, Diane E., Visel, Axel, Pennacchio, Len A., Ren, Bing“…The Encyclopedia of DNA Elements (ENCODE) project has established a genomic resource for mammalian development, profiling a diverse panel of mouse tissues at 8 developmental stages from 10.5 days after conception until birth, including transcriptomes, methylomes and chromatin states. …”
Publicado 2020
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9206“…Gene Ontology biological processes and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were conducted using the clusterProfiler package in R3.4.1. …”
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9207“…A Gene Ontology enrichment analysis generated 47,091 assignments to biological processes, 5,250 assignments to cellular components, and 6,466 assignments to molecular functions. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed that the Wnt and MAPK signaling pathways were significantly enriched. …”
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9208por Ding, Yangyang, Xue, Xianglan, Liu, Zhanfa, Ye, Yong, Xiao, Ping, Pu, Yabin, Guan, Weijun, Mwacharo, Joram Mwashigadi, Ma, Yuehui, Zhao, Qianjun“…An analysis of the target genes of the above-mentioned DE miRNAs by the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses indicated that the DE miRNAs were involved in signal pathways which were previously associated with hair bending and hair follicle development, such as the TGF-β/SMAD, PI3K-Akt, JAK-STAT, and MAPK pathways. …”
Publicado 2020
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9209por Van Nostrand, Eric L., Freese, Peter, Pratt, Gabriel A., Wang, Xiaofeng, Wei, Xintao, Xiao, Rui, Blue, Steven M., Chen, Jia-Yu, Cody, Neal A. L., Dominguez, Daniel, Olson, Sara, Sundararaman, Balaji, Zhan, Lijun, Bazile, Cassandra, Bouvrette, Louis Philip Benoit, Bergalet, Julie, Duff, Michael O., Garcia, Keri E., Gelboin-Burkhart, Chelsea, Hochman, Myles, Lambert, Nicole J., Li, Hairi, McGurk, Michael P., Nguyen, Thai B., Palden, Tsultrim, Rabano, Ines, Sathe, Shashank, Stanton, Rebecca, Su, Amanda, Wang, Ruth, Yee, Brian A., Zhou, Bing, Louie, Ashley L., Aigner, Stefan, Fu, Xiang-Dong, Lécuyer, Eric, Burge, Christopher B., Graveley, Brenton R., Yeo, Gene W.“…Here we introduce a new data set of RNA elements in the human genome that are recognized by RNA-binding proteins (RBPs), generated as part of the Encyclopedia of DNA Elements (ENCODE) project phase III. …”
Publicado 2020
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9210“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment pathway analyses were explored to predict the possible roles of m5C. …”
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9211por Guo, Weiwei, Han, Liping, Li, Ximei, Wang, Huifang, Mu, Ping, Lin, Qi, Liu, Qingchang, Zhang, Yumei“…Biosynthetic process, transcriptional regulation, ribosome and proteasome pathway related proteins were significantly enriched in both differentially expressed proteins and differentially acetylated proteins through Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis. …”
Publicado 2020
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9212“…The Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that the DEPs were mainly enriched in the activation of immune cells (drug metabolism pathway, NOD-like pathway, and IL-17 pathway), cell proliferation (ribosomal pathway, DNA replication pathway, and base replication pathway), metabolism-related pathways (fatty acid biosynthesis and metabolism, PPAR pathway, glycerophospholipid metabolism, and cortisol synthesis and breakdown), and glandular secretion (saliva secretion, gastric acid secretion, and pancreatic fluid secretion). …”
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9213por Xu, Wenjun, Lu, Zhongxia, Wang, Xin, Cheung, Man Hei, Lin, Meiai, Li, Changyu, Dong, Yu, Liang, Chun, Chen, Yitao“…Potential target genes were predicted using PharmMapper and analyzed using Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO). …”
Publicado 2020
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9214por Lyu, Lijuan, Yao, Jia, Wang, Meng, Zheng, Yi, Xu, Peng, Wang, Shuqian, Zhang, Dai, Deng, Yujiao, Wu, Ying, Yang, Si, Lyu, Jun, Guan, Feng, Dai, Zhijun“…Functionally, gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes enrichment analysis indicated that the HLA-DPB2/HLA-DPB1 axis was strongly relevant to immune-related biological functions. …”
Publicado 2020
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9215por Chen, Jiarui, Liu, Chong, Cen, Jiemei, Liang, Tuo, Xue, Jiang, Zeng, Haopeng, Zhang, Zide, Xu, Guoyong, Yu, Chaojie, Lu, Zhaojun, Wang, Zequn, Jiang, Jie, Zhan, Xinli, Zeng, Jian“…METHODS: The gene expression profiling (GSE86945, GSE86946 and GSE102088) data were obtained from Gene Expression Omnibus Datasets, DEGs were identified by using R software, Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of DEGs were performed by the Database for Annotation, Visualization and Integrated Discovery (DAVID) tools, and the protein-protein interaction (PPI) network of the DEGs was constructed by the STRING database and visualized by Cytoscape software. …”
Publicado 2020
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9216por Fan, Xuehui, Liu, Lili, Shi, Yue, Guo, Fanghan, Wang, Haining, Zhao, Xiuli, Zhong, Di, Li, Guozhong“…To identify related pathways and perform functional annotation of RBP DEGs, Gene Ontology (GO) function and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were carried out using the database for annotation, visualization and integrated discovery. …”
Publicado 2020
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9217“…Functional and pathway enrichment analysis were performed based on Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. STRING, Cytoscape and MCODE were applied to construct a protein-protein interaction (PPI) network and to screen hub genes. …”
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9218“…The gene ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichments of DEGs were operated by the database for annotation, visualization and integrated discovery and KEGG orthology based annotation system databases, separately. …”
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9219por Tan, Juan, Liu, Ling, Zuo, Zhihua, Song, Bin, Cai, Tingting, Ding, Dafa, Lu, Yibing, Ye, Xiaolong“…Functional enrichment analysis indicated that LINC02454-related genes were significantly enriched in Gene Ontology terms, such as ‘positive regulation of cell proliferation’, ‘positive regulation of cell division’ and ‘cell adhesion’, and the following Kyoto Encyclopedia of Genes and Genomes pathways: ‘Pathways in cancer’ ‘proteoglycans in cancer’ and ‘ECM-receptor interaction’. …”
Publicado 2020
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9220por Zhang, Mi, Chen, Zexi, Zhang, Sihui, Wu, Ling, Jie, Yinghui, Liao, Yunyang, Huang, Yue, Chen, Jiang, Shi, Bin“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to demonstrate the principal functions of the significantly dysregulated lncRNAs and genes. …”
Publicado 2020
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