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9421por Zhang, Yun-Qiang, Yuan, Ye, Zhang, Jun, Lin, Cheng-Yi, Guo, Jia-Long, Liu, Hua-Song, Guo, Qiang“…The mechanism of action involved in the PD-1 target molecules via the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). The protein-protein interaction (PPI) network shows the relationship between PD-1 target molecules. …”
Publicado 2021
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9422por Xiao, Cheng, Wei, Tian, Liu, Li Xiang, Liu, Jian Qiang, Wang, Chun Xin, Yuan, Zhi Yu, Ma, Hui Hai, Jin, Hai Guo, Zhang, Li Chun, Cao, Yang“…Gene Ontology analysis showed that most DERs enriched in Cell Part, Cellular Process, Biological Regulation, and Binding terms. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis found that the DERs primarily focused on Focal adhesion, phosphoinositide 3-kinase (PI3K)-Akt, mitogen-activated protein kinase (MAPK), peroxisome proliferator-activated receptor (PPAR) signaling pathways. …”
Publicado 2021
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9423por Dou, Xiaobing, Yang, Wenwen, Ding, Qinchao, Han, Qiang, Qian, Qianyu, Du, Zhongyan, Fan, Yibin, Wang, Cui, Li, Songtao“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were used to enrich the functions of these lncRNAs. …”
Publicado 2021
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9424“…Gene Ontology analysis results demonstrated that the upregulated and downregulated genes were primarily enriched in ‘cellular process’, ‘metabolic process’ and ‘biological regulation’. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis revealed that the upregulated genes were primarily enriched in ‘cysteine and methionine metabolism’, ‘oxidative phosphorylation’ and ‘ribosome’, whereas the downregulated genes were primarily enriched in the ‘transcriptional misregulation in cancer’, ‘ribosome’ and ‘mitophagy-animal’ pathways. …”
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9425“…Moreover, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were performed for exploring the potential functions and biological pathways. …”
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9426por Liu, Na, Zhong, Liang, Ni, Guangcheng, Lin, Jiao, Xie, Liang, Li, Taiwen, Dan, Hongxia, Chen, Qianming“…MMP28-correlated genes in the TCGA-PAAD cohort were identified and enrichment analysis according to the Gene Ontology and Kyoto Encyclopedia of Genes and Genomes was conducted using LinkedOmics. …”
Publicado 2021
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9427por Su, Tong, Hou, Jiejun, Liu, Tonghua, Dai, Pei, Qin, LingLing, Ding, Lei, Hu, Yan, Guo, Xiangyu“…The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were used to predict the target genes related to each of the identified miRNAs and the functions of these target genes in different metabolic signaling pathways. …”
Publicado 2021
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9428por Zhang, Shaoli, Gu, Xin, Shao, Jingcheng, Hu, Zhifeng, Yang, Wencai, Wang, Liping, Su, Hongyan, Zhu, Luying“…Furthermore, KEGG (Kyoto Encyclopedia of Genes and Genomes) enrichment analyses of transcriptomic data identified 175 differentially expressed genes (DEGs) related to plant hormone signal transduction, including 63 auxin-related genes, 27 abscisic acid-related genes, 22 ethylene-related genes, 16 cytokinin-related genes, 16 salicylic acid-related genes, 14 brassinosteroid-related genes, 13 jasmonic acid-related genes, and 4 gibberellin-related genes at −2 DAA and 0 DAA. …”
Publicado 2021
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9429“…Finally, we used the MCPCounter algorithm to study the relationship between the risk model and immune cell infiltration, and used gene set enrichment analysis (GSEA), Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses to explore the enrichment pathways and biological processes of differentially expressed genes between the high- and low-risk groups. …”
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9430por Wang, Nan, Gu, Yuanting, Chi, Jiangrui, Liu, Xinwei, Xiong, Youyi, Zhong, Chaochao, Wang, Fang, Wang, Xinxing, Li, Lin“…Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes analysis were performed by using gene set enrichment analysis (GSEA). …”
Publicado 2021
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9431por Luo, Chao, Zhou, Xiongcai, Wang, Li, Zeng, Qinyu, Fan, Junhong, He, Shuhua, Zhang, Haibo, Wei, Anyang“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of ARGs were described using clusterProfiler and org.Hs.eg.db in R. …”
Publicado 2021
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9432por Zhang, Junfang, Li, Qiang, Yan, Yan, Sun, Bin, Wang, Ying, Tang, Lin, Wang, Enze, Yu, Jia, Nogoy, Kim Margarette Corpuz, Li, Xiangzi, Choi, Seong-Ho“…DEGs gene ontology (GO) analysis showed that the top 10 GO enrichment significantly changed the biological processes such as protein trimerization, negative regulation of cell proliferation, adipocytes differentiation, and cellular response to external stimulus. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that DEGs were involved in the p53 signaling pathway, PPAR signaling pathway, biosynthesis of amino acids, tumor necrosis factor signaling pathway, non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, and Wnt signaling pathway. …”
Publicado 2021
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9433por Zheng, Xu, Su, Huimin, Wang, Liping, Yao, Ruiyuan, Ma, Yuze, Bai, Linfeng, Wang, Yanfeng, Guo, Xudong, Wang, Zhigang“…The mitogen-activated protein kinase (MAPK) signaling pathway was found to play a potentially important role in the interaction network involved in the response to amino acid signals, according to gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and MAPK1/3 may serve as a central hub for the entire network. …”
Publicado 2021
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9434“…Among the 186 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, there were three and four KEGG pathways, which partially explained the molecular mechanisms by which B cell and DC1 simultaneously predicted the prognosis and efficacy of immunotherapy, respectively. …”
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9435“…We performed Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis of DEGs. …”
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9436por Gan, Xiao-xiong, Li, Ya-yi, Li, Si-jin, Mo, Shi-sen, Feng, Jian-hua, Shen, Fei, Cai, Wen-song, Lai, Ye-qian, Xu, Bo“…Gene Ontology (GO) and Kyoto Gene and Genomic Encyclopedia (KEGG) pathway enrichment analyses were performed using single-sample gene set enrichment analysis (ssGSEA). …”
Publicado 2021
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9437por Yang, Libo, Li, Chunyan, Qin, Yang, Zhang, Guoying, Zhao, Bin, Wang, Ziyuan, Huang, Youguang, Yang, Yong“…Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and single-sample gene set enrichment analysis (ssGSEA) were used to explore underlying mechanisms. …”
Publicado 2021
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9438por Zhao, Ye, Liu, Lixiao, Zhao, Jinduo, Du, Xuedan, Yu, Qiongjie, Wu, Jinting, Wang, Bin, Ou, Rongying“…METHODS: Here, we accessed the data from The Cancer Genome Atlas for model construction and performed Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses to identify biological functions. …”
Publicado 2021
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9439por Geng, Hui, Liu, Guangli, Hu, Jiandong, Li, Jianchao, Wang, Dong, Zou, Shenshan, Xu, Xintao“…The expression of HOXB13 in GC cells was first examined using the Cancer Cell Line Encyclopedia database and subsequently validated in a number of GC cell lines. …”
Publicado 2021
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9440por Liu, Zhiguo, Liu, Hongyan, Dong, Qian, Li, Hongyu, Zhang, Bin, Liu, Yufeng, Zhong, Limei, Tang, Haikuo“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses showed that DFNA5 expression has a strong positive correlation with cell adhesion and the integrin signaling pathway, whereas its expression was negatively correlated with the levels of infiltrating B cells (cor = − 0.223, P = 8.57e-07) and CD8 T cells (cor = − 0.223, P = 2.99e-07). …”
Publicado 2021
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