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10501“…Further, gene ontology (GO) analysis as well as Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed. …”
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10502“…RESULTS: We found that FGF-2 was downregulated in the DEX-treated group. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses indicated that DEGs were associated with PI3K/Akt signaling pathway. …”
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10503“…The hub genes were then obtained via protein-protein interaction (PPI) analysis. Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA) were subsequently performed. …”
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10504por Wang, Fang, An, Shu-Jing, Yin, Yirong, Li, Juan-Juan, Sun, Chun-Hui, Lan, Jie, Zhao, Wen-Juan, Li, Cheng-Qian“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses of the core PPI network were obtained. …”
Publicado 2021
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10505“…Co-expression analysis, Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis were conducted to explore their potential functions and related signaling pathways. …”
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10506por Ye, Yuchu, Wang, Jingyi, Liang, Faya, Song, Pan, Yan, Xiaoqing, Wu, Sangqing, Huang, Xiaoming, Han, Ping“…Gene Ontology (GO) enrichment analysis showed that the biological functions of DEGs focused primarily on the apical plasma membrane and regulation of anoikis. Kyoto Encyclopedia of Genes and Genomes (KEGG) signalling pathway analysis showed that these DEGs were mainly involved in drug metabolism-cytochrome P450 and serotonergic synapses. …”
Publicado 2021
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10507“…The networks analysed were protein-protein interaction (PPI), drug-component-target gene, component-target gene-organ, and target gene-extended disease; we also performed gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. RESULTS: In total, 34 sedative-hypnotic components (including 5 central active components) were identified, corresponding to 51 target genes. …”
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10508“…Gene Ontology (GO) analysis and the Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to investigate the functions of HSPA4 and its functional partner genes. …”
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10509“…Enrichment analysis of Gene Ontology (GO) biological processes (BPs) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment were established based on DAVID. …”
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10510por Brycki, Joshua D., Chen See, Jeremy R., Letson, Gillian R., Emlet, Cade S., Unverdorben, Lavinia V., Heibeck, Nathan S., Brislawn, Colin J., Buonaccorsi, Vincent P., Chan, Jason P., Lamendella, Regina“…Differential analysis of the E. coli transcriptome yielded 22 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and 100 KEGG genes enriched when samples were grouped by time point [LDA, linear discriminant analysis; log(LDA), ≥2; P ≤ 0.05], including several involved in biofilm formation. …”
Publicado 2021
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10511por Chen, Qu, Wu, Chen, Yao, Zhihao, Cai, Liuping, Ni, Yingdong, Mao, Shengyong, Zhao, Ruqian“…Gene Ontology (GO) annotation revealed that the differentially expressed genes were mainly enriched in oxidoreductase activity, stress, metabolism, the immune response, cell apoptosis, and cell proliferation. Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that the deferentially expressed genes were highly enriched in the phosphatidylinositol 3 kinase (PI3K)-serine/threonine kinase (AKT) signaling pathway (P < 0.05). …”
Publicado 2021
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10512“…Subsequently, Gene Ontology (GO) functional term and Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway enrichment analyses of the target genes of differentially expressed miRNAs of interest were performed. …”
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10513por Zhao, L., Zhang, Y., Liu, F., Yang, H., Zhong, Y., Wang, Y., Li, S., Su, Q., Tang, L., Bai, L., Ren, H., Zou, Y., Wang, S., Zheng, S., Xu, H., Li, L., Zhang, J., Chai, Z., Cooper, M. E., Tong, N.“…METHODS: Untargeted proteomic and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional analyses and targeted proteomic analysis using parallel reaction-monitoring (PRM)-mass spectrometry was performed to determine the abundance of urinary complement proteins in healthy controls, type 2 diabetes mellitus (T2DM) patients, and patients with T2DM and biopsy-proven DN. …”
Publicado 2021
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10514“…The clusterProfiler package in R was used to perform a biological process (BP) analysis of gene ontology (GO), and a Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis was performed separately in upregulated and downregulated groups. …”
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10515por Tu, Guangxu, Peng, Weilin, Cai, Qidong, Zhao, Zhenyu, Peng, Xiong, He, Boxue, Zhang, Pengfei, Shi, Shuai, Wang, Xiang“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were conducted to determine the main biological function and molecular pathways of the differentially expressed GI-lncRNAs. …”
Publicado 2021
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10516“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of age-related DEGs were performed by clusterProfiler of R. …”
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10517Pan-Cancer Analysis of IGF-1 and IGF-1R as Potential Prognostic Biomarkers and Immunotherapy Targetspor Zhang, Yinqi, Gao, Chengqi, Cao, Fei, Wu, Ying, Chen, Shuanggang, Han, Xue, Mo, Jingqin, Qiu, Zhiyu, Fan, Weijun, Zhou, Penghui, Shen, Lujun“…METHOD: This research comprehensively analyzed the expression pattern of IGF-1 and IGF-1R and the influence of IGF-1 and IGF-1R on clinical significance in prognosis prediction among 33 types of malignancies using The Cancer Genome Atlas (TCGA) and the Cancer Cell Line Encyclopedia (CCLE) databases. The correlation between IGF-1, IGF-1R, and cancer immunity was explored. …”
Publicado 2021
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10518por Zhang, Xue, Wei, Xuan, Bai, Gaigai, Huang, Xueyao, Hu, Shunxue, Mao, Hongluan, Liu, Peishu“…METHODS: Based on the RNA-seq data of tissues in The Cancer Genome Atlas (TCGA) and RNA-seq data of cells from the Cancer Cell Encyclopedia (CCLE), we integrated differentially expressed genes (DEGs) in ovarian cancer tissue and cells. …”
Publicado 2021
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10519Transcriptome sequencing identified the ceRNA network associated with recurrent spontaneous abortionpor Huang, Yong, Hao, Jiayuan, Liao, Yuan, Zhou, Lihua, Wang, Kaiju, Zou, Hui, Hu, Ying, Li, Juan“…Differentially expressed lncRNAs, miRNAs and genes (DELs, DEMs and DEGs, respectively) were identified, and Geno Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were used to determine the functions of DELs and DEGs, which were analysed by Fisher’s test. …”
Publicado 2021
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10520por Yang, Jiangtao, Gao, Lihua, Liu, Xiaojing, Zhang, Xiaochun, Wang, Xujing, Wang, Zhixing“…Subsequently, Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathway analyses were performed, which revealed that these genes were mainly involved in catalytic activity, carbohydrate metabolism, the cell membrane and organelles, signal transduction and other functions and metabolic pathways. …”
Publicado 2021
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