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10561“…Furthermore, transcriptome sequencing and tandem mass tag-based quantitative proteome analyses identified 14,376 differentially expressed genes (DEGs) and 1,819 differentially expressed proteins (DEPs). The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis indicated that glutathione metabolism and phenylpropanoid biosynthesis were the main two shared enriched pathways across ratio comparisons. …”
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10562por Weng, Kongyan, Huang, Yinger, Deng, Hao, Wang, Ruixue, Luo, Shuhong, Wu, Hongfeng, Chen, Jialing, Long, Mingjian, Hao, Wenbo“…We used the Gene Expression Omnibus (GEO) database to identify differentially expressed genes (DEGs), the DAVID online tool to perform Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of DEGs, the STRING database to construct the protein-protein interaction (PPI) network of DEGs, the Oncomine and the Cancer Genome Atlas-Stomach Adenocarcinoma (TCGA-STAD) databases to analyze the gene expression differences, the Human pan-Cancer Methylation database (MethHC) to compare the DNA methylation of genes, and the Kaplan-Meier plotter to show the survival analysis of DEGs. …”
Publicado 2020
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10563“…The bioinformatic analysis of the differentially expressed genes was performed by Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis. …”
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10564por Wang, Yaping, Zhao, Shujun, Zhang, Xinlu, Zhu, Hai, Ji, Xiaorong, Jiang, Yi, Meng, Jie, Shi, Hongyu, Gao, Xiang, Zhang, Xiaoan, Li, Hongyu“…Finally, the Tim-3 function was carried out using Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and a gene set enrichment analysis (GSEA) was performed. …”
Publicado 2020
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10565por Gao, Cheng, Shen, Jianbo, Yao, Lanqing, Xia, Zhenguo, Liang, Xiaoliang, Zhu, Renfei, Chen, Zhong“…LinkedOmics was used to analyze the relationship of AQP9 with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Mechanistically, mir-23a-3p and mir-330-3p may downregulate AQP9 expression in HCC. …”
Publicado 2021
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10566por Zhang, Xiao-Bin, Lin, Xiu-Li, Wu, Xin-Yu, Zeng, Yi-Ming, Chen, Xiao-Yang, Luo, Xiongbiao, Zeng, Hui-Qing“…Gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) pathway were performed to reveal the functional enrichment of the target genes regulated by the miRNAs. …”
Publicado 2020
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10567“…Functional annotation and pathway enrichment analysis of DEmRNAs were performed using the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases. The miRNAs that are targeted by lncRNAs were predicted using miRanda and PITA, while the target mRNAs of miRNAs were retrieved from miRanda, miRWalk, and TargetScan. …”
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10568por Liu, Huan, Liu, Boxuan, Zhang, Lei, Li, Mingzhen, Chen, Cheng, He, Shaohua, Luo, Tingting, He, Xiaohui, Tan, Liming“…The functional assessments were performed include Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and protein–protein interaction (PPI) analyses. …”
Publicado 2021
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10569por Zhang, Zhi, Zou, Zhenning, Dai, Haixia, Ye, Ruifang, Di, Xiaoqing, Li, Rujia, Ha, Yanping, Sun, Yanqin, Gan, Siyuan“…Then, we applied the Database for Annotation, Visualization and Integrated Discovery for Kyoto Encyclopedia of Gene and Genome pathway and gene ontology (GO) analyses. …”
Publicado 2020
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10570por Chen, Xiaomin, Wang, Ruoyu, Xu, Tianze, Zhang, Yajing, Li, Hongyan, Du, Chengcheng, Wang, Kun, Gao, Zairong“…The upregulated and downregulated DEGs, along with the modules of interest, were subjected to Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment using the Database for Annotation, Visualization, and Integrated Discovery (DAVID). …”
Publicado 2021
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10571por Li, Changhao, Zhu, Zhenyu, Hou, Qingsheng, Wang, Bishi, Zou, Lei, Liu, Luguang, Gong, Weipeng, Guo, Hongliang“…Biological processes in the Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases were analyzed for specific miRNAs, lncRNAs, and mRNAs. …”
Publicado 2021
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10572por Yao, Ruixue, Chen, Xiaoming, Wang, Luyao, Wang, Yuanyong, Chi, Shaoli, Li, Na, Tian, Xuejun, Li, Nan, Liu, Jia“…The differentially expressed genes were clarified by Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, the protein-protein interaction (PPI) network and statistical analyses. …”
Publicado 2019
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10573por Hu, Menglong, Li, Zongkuo, Qiu, Jinhuan, Zhang, Ruizhen, Feng, Junkai, Hu, Guiming, Ren, Jingli“…Abbreviations: LGG: lower grade glioma; CKS2: CDC28 protein kinase regulatory subunit 2; TCGA: The Cancer Genome Atlas; CGGA: the Chinese Glioma Genome Atlas; GEO: Gene Expression Omnibus; GEPIA: Gene Expression Profiling Interactive Analysis; TIMER: Tumor Immune Estimation Resource; IHC: immunohistochemistry; qRT-PCR: quantitative real-time polymerase chain reaction; PBS: phosphate buffered saline; DAB: diaminobenzidine tetrachloride; OS: overall survival; CAN: copy number alteration; IDH: Isocitrate dehydrogenase; GSEA: Gene Set Enrichment Analysis; DEG: differentially expressed gene; KEGG: Kyoto encyclopedia of genes and genomes; GO: Gene ontology; BP: biological process; CC: cellular component; MF: molecular function; NES: normalized enrichment score; NOM: nominal; FDR: false discovery rate…”
Publicado 2021
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10574por Zhen, Jianhua, Zhao, Pengfei, Li, Yini, Cai, Yanan, Yu, Wanchen, Wang, Wei, Zhao, Lu, Wang, Hesong, Huang, Guangrui, Xu, Anlong“…The functional analysis was performed according to the Kyoto Encyclopedia of Genes and Genomes (KEGG) dataset. The allergy-related cytokines, IL-4, IL-6 and IL-13, were measured to evaluate the effect of indole derivatives on LPS-induced macrophage activation. …”
Publicado 2022
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10575“…The results of Kyoto Encyclopedia of Genes and Genomes analysis showed that miR-4722-5p was associated with the regulation of dopaminergic synapses and mTOR signaling pathways. …”
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10576por Yi, Yuanxue, Zhang, Qiufang, Shen, Youfeng, Gao, Yueyi, Fan, Xiaohong, Chen, Sini, Ye, Xin, Xu, Jian“…OBJECTIVE: To identify new tumor marker genes available for early tumor screening, differentially expressed gene profiles of multiple tumors were compared using Genotype-Tissue Expression (GTEx), Cancer Cell Line Encyclopedia (CCLE), and The Cancer Genome Atlas (TCGA) databases. …”
Publicado 2022
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10577por Chen, Zhipeng, Lin, Wei, Zhao, Shengli, Mo, Xiaoyi, Wen, Zhenxing, Cheung, Wing Hoi, Fu, Dan, Chen, Bailing“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to predict the functions of differentially expressed circRNAs. …”
Publicado 2022
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10578“…Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were performed. …”
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10579por Yang, Xiaocheng, Yin, Fanxing, Liu, Qingyang, Ma, Yue, Zhang, Hao, Guo, Panpan, Wen, Wen, Guo, Xu, Wu, Yihao, Yang, Zhuo, Han, Yanshuo“…Functional analyses, including Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and single-sample Gene Set Enrichment Analysis (ssGSEA), were conducted to explore the underlying mechanisms in the development and prognosis of CESC. …”
Publicado 2022
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10580por Jiang, Gang, Hassan, Muhammad A., Muhammad, Noor, Arshad, Muhammad, Chen, Xiang, Xu, Yonghan, Xu, Hui, Ni, Qianqian, Liu, Binbin, Yang, Wenkang, Li, Jincai“…Several transcriptome changes were observed through Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway functional enrichment analysis in plant hormone signal transduction, circadian rhythm-plant, and starch and sucrose metabolism under low temperature. …”
Publicado 2022
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