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  1. 11201
    “…Protein-protein interaction analysis was performed in the GeneMANIA database, and enrichment analysis and identification of predicted signaling pathways were performed using Gene Ontology and Kyoto Encyclopedia of Genes. Additionally, the Cox regression was used to assess the clinicopathologic features linked to the overall survival in TCGA patients. …”
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    High Expression of TACC3 Is Associated with the Poor Prognosis and Immune Infiltration in Lung Adenocarcinoma Patients
  2. 11202
    por Lonjou, Christine, Eon‐Marchais, Séverine, Truong, Thérèse, Dondon, Marie‐Gabrielle, Karimi, Mojgan, Jiao, Yue, Damiola, Francesca, Barjhoux, Laure, Le Gal, Dorothée, Beauvallet, Juana, Mebirouk, Noura, Cavaciuti, Eve, Chiesa, Jean, Floquet, Anne, Audebert‐Bellanger, Séverine, Giraud, Sophie, Frebourg, Thierry, Limacher, Jean‐Marc, Gladieff, Laurence, Mortemousque, Isabelle, Dreyfus, Hélène, Lejeune‐Dumoulin, Sophie, Lasset, Christine, Venat‐Bouvet, Laurence, Bignon, Yves‐Jean, Pujol, Pascal, Maugard, Christine M., Luporsi, Elisabeth, Bonadona, Valérie, Noguès, Catherine, Berthet, Pascaline, Delnatte, Capucine, Gesta, Paul, Lortholary, Alain, Faivre, Laurence, Buecher, Bruno, Caron, Olivier, Gauthier‐Villars, Marion, Coupier, Isabelle, Mazoyer, Sylvie, Monraz, Luis‐Cristobal, Kondratova, Maria, Kuperstein, Inna, Guénel, Pascal, Barillot, Emmanuel, Stoppa‐Lyonnet, Dominique, Andrieu, Nadine, Lesueur, Fabienne
    Publicado 2021
    “…Furthermore, 31 Kyoto Encyclopedia of Genes and Genomes and 7 Atlas of Cancer Signaling Network pathways were highlighted (false discovery rate of 5%). …”
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    Gene‐ and pathway‐level analyses of iCOGS variants highlight novel signaling pathways underlying familial breast cancer susceptibility
  3. 11203
    “…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analysis revealed that differential m(6)A modifications were more enriched in functions and cellular signalling pathways related to cardiomyocyte proliferation. …”
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    N6-methyladenosine modulates long non-coding RNA in the developing mouse heart
  4. 11204
    “…On the basis of the identified components, we performed target prediction using the SwissTargetPrediction database, protein–protein interaction (PPI) analysis using STRING database, and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis using Metascape and constructed a component-target-pathway network using Cytoscape 3.7.2. …”
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    Systematic characterization of the components and molecular mechanisms of Jinshui Huanxian granules using UPLC-Orbitrap Fusion MS integrated with network pharmacology
  5. 11205
    “…The WebGestalt online tool was used to identify DEGs enriched in biological processes, molecular functions, cellular components, and Kyoto Encyclopedia of Genes and Genomes pathways. The protein–protein interactions of DEGs were visualized using Cytoscape with STRING. …”
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    Differences of core genes in liver fibrosis and hepatocellular carcinoma: Evidence from integrated bioinformatics and immunohistochemical analysis
  6. 11206
    “…Furthermore, its biological function and the related hallmark pathways were assessed through Gene Ontology (GO) annotation, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, and Gene-set enrichment analysis (GSEA). …”
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    Novel LncRNA ZFHX4-AS1 as a Potential Prognostic Biomarker That Affects the Immune Microenvironment in Ovarian Cancer
  7. 11207
    “…Protein–protein interaction (PPI) analysis obtained the core target genes in the intersection target, and then imported the intersection target into the David database for gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) analysis. Furthermore, the therapeutic effect of paeoniflorin, the main component of PLP, on IgE-induced type I allergy was evaluated in vitro. …”
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    Network pharmacology-based analysis and experimental in vitro validation on the mechanism of Paeonia lactiflora Pall. in the treatment for type I allergy
  8. 11208
    por Li, Chenyang, Lu, Yongping, Han, Xiuping
    Publicado 2022
    “…Functional enrichment analysis was performed for these co-DEGs using Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG), followed by protein-protein interaction network analysis. …”
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    Identification of Effective Diagnostic Biomarkers and Immune Cell Infiltration in Atopic Dermatitis by Comprehensive Bioinformatics Analysis
  9. 11209
    “…Cytoscape software was used to generate a competing endogenous RNA (ceRNA) network of competitive endogenous mechanism of serum exosomes in ovarian cancer, and the R language was used for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of the target genes. …”
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    Analysis of Competitive Endogenous Mechanism and Survival Prognosis of Serum Exosomes in Ovarian Cancer Patients Based on Sequencing Technology and Bioinformatics
  10. 11210
    “…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis of ARGs were performed by the “clusterprofile” R package. …”
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    Prognostic Model and Nomogram Construction and Validation With an Autophagy-Related Gene Signature in Low-Grade Gliomas
  11. 11211
    por Xie, Chengmao, Yin, Ziran, Liu, Yong
    Publicado 2022
    “…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were conducted by the “clusterProfiler” R package. …”
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    Analysis of characteristic genes and ceRNA regulation mechanism of endometriosis based on full transcriptional sequencing
  12. 11212
    por Antoranz, Asier, Ortiz, María, Pey, Jon
    Publicado 2022
    “…We validated the proposed methodology using a set of 452 cancer cell lines derived from the Cancer Cell Line Encyclopedia where an exhaustive experimental large-scale gene knockout study using CRISPR (Achilles Project) evaluates the impact of each removal. …”
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    ELIMINATOR: essentiality analysis using multisystem networks and integer programming
  13. 11213
    “…The signaling pathways related to PANK1 expression were identified by Gene Ontology (GO) investigation and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. The Tumor Immune Estimation Resource database was used to analyze the correlation between PANK1 and tumor-infiltrating immune cells. …”
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    PANK1 associates with cancer metabolism and immune infiltration in clear cell renal cell carcinoma: a retrospective prognostic study based on the TCGA database
  14. 11214
    “…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses of the common targets were performed using the DAVID 6.8 database to elucidate the mechanism of zedoary turmeric-trisomes in the treatment of IBD. …”
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    Network pharmacology and molecular docking reveal zedoary turmeric-trisomes in Inflammatory bowel disease with intestinal fibrosis
  15. 11215
    “…There were 644 common DEGs and 167 common five-fold higher differentially expressed genes (HDEGs) identified, and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed using the Database for Annotation, Visualization and Integrated Discovery (DAVID). …”
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    High-throughput transcriptome sequencing reveals the key stages of cardiovascular development in zebrafish embryos
  16. 11216
    “…Proteins were quantitated via tandem mass tag-based liquid chromatography-mass spectrometry and bioinformatics analyses, and 34 differentially expressed proteins were confirmed using parallel reaction monitoring, which were defined as new indicators related to the mechanism underlying DNA damage; glutathione perturbation; mitogen-activated protein kinase; and the Wnt and ErbB signaling pathways in VI based on Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and protein–protein interaction network analyses. …”
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    Proteomics-based evaluation of the mechanism underlying vascular injury via DNA interstrand crosslinks, glutathione perturbation, mitogen-activated protein kinase, and Wnt and ErbB signaling pathways induced by crotonaldehyde
  17. 11217
    “…Functional analyses including gene ontology, Kyoto Encyclopedia of Genes and Genomes (KEGG), gene set variation analysis, and gene set enrichment analysis analyses were conducted to elucidate the underlying mechanisms. ssGSEA algorithm was performed to uncover the immune characteristics. …”
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    Novel insight into m6A regulator-mediated methylation modification patterns and immune characteristics in intracranial aneurysm
  18. 11218
    “…Meanwhile, we built a competing endogenous RNA (ceRNA) network based on the model genes and explored the related pathways and immune correlation involved in the two diseases by using Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and gene set enrichment analyses. …”
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    Screening of co-pathogenic genes of non-alcoholic fatty liver disease and hepatocellular carcinoma
  19. 11219
    “…Furthermore, 170 differentially expressed intersection genes were screened and analyzed for Gene Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment. …”
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    SPP1/AnxA1/TIMP1 as Essential Genes Regulate the Inflammatory Response in the Acute Phase of Cerebral Ischemia-Reperfusion in Rats
  20. 11220
    “…Abbreviations: BUN: blood urea nitrogen; CKD: chronic kidney disease; CKD-MBD: chronic kidney disease-mineral bone disorder; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GO: the Gene Ontology; HE: hematoxylin-eosin; HRP: horseradish peroxidase; KEGG: Kyoto Encyclopedia of Genes and Genomes; MiRNAs: microRNAs; PAS: periodic acid-Schiff; RUNX2: runt-related transcription factor 2; SCr: serum creatinine; STRING: the Search Tool for the Retrieval of Interacting Genes/Proteins; TAGLN: transgelin; VSMC: vascular smooth muscle cell.…”
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    Sclerostin is involved in osteogenic transdifferentiation of vascular smooth muscle cells in chronic kidney disease-associated vascular calcification with non-canonical Wnt signaling
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