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11261“…By intersecting these two DEG sets, we generated common DEGs for further analysis, containing Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway and Gene Ontology (GO) functional enrichment analysis, protein-protein interaction (PPI) analysis, transcription factor (TF) candidate identification, microRNAs (miRNAs) candidate identification and drug candidate identification. …”
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11262“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses were performed to predict the function of DEcircRNAs. …”
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11263por Zhang, Churen, Sun, Yuzhe, Xu, Min, Shu, Chang, Yue, Zhaoguo, Hou, Jianxia, Ou, Dongchen“…The analysis of Gene Ontology, Kyoto Encyclopedia of Genesand Genomes pathway, and protein–protein interaction network was conducted for the shared differentially expressed genes. …”
Publicado 2022
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11264“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses of hub genes were performed with R package clusterProfiler. …”
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11265por Xu, Lieqiang, Cheng, Juanjuan, Lu, Jieyi, Lin, Guoshu, Yu, Qiuxia, Li, Yucui, Chen, Jiannan, Xie, Jianhui, Su, Ziren, Zhou, Qi“…The core targets of CP for treating HUA were TP53, MAPK8, MAPK3, IL-6, c-Jun, AKT1, xanthine oxidase (XOD), and ATP-binding cassette subfamily G member 2 (ABCG2). The Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment results showed that the anti-HUA effect of CP mainly involved the pathways of inflammation and apoptosis, such as PI3K/Akt, TNF, MAPK, TLR, AMPK, NF-κB, and NLRP3 signaling pathways. …”
Publicado 2022
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11266por Zhang, Li-Hua, Zhuo, Hui-Qin, Hou, Jing-Jing, Zhou, Yang, Cheng, Jia, Cai, Jian-Chun“…The DEPs were functionally annotated using clusterProfiler, STRING and DAVID for Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. P < 0.05 was considered statistically significant. …”
Publicado 2022
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11267“…To analyze the potential signaling pathways with SIX family involvement, LinkedOmics was used to perform Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses of SIX4-related genes. …”
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11268por Hamzah, Siti Nasuha, Avicor, Silas Wintuma, Alias, Zazali, Razak, Sarah Abdul, Bakhori, Siti Khadijah Mohd, Hsieh, Ting Chuan, Syanizam, Nurin Nazifa, Farouk, Salinah Abdul“…In the PPI analysis, 12 common enriched pathways of Kyoto Encyclopedia of Genes and Genomes (KEGG) were found to be intercorrelated with the identified GSTs at PPI enrichment p-value < 1.0 × 10(−16). …”
Publicado 2022
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11269por Yousuf, Tahira, Dar, Sadaf Bashir, Bangri, Sadaf Ali, Choh, Naseer A., Rasool, Zubaida, Shah, Altaf, Rather, Rafiq Ahmed, Rah, Bilal, Bhat, Gh Rasool, Ali, Shazia, Afroze, Dil“…To anticipate the potential biological roles of a three-miRNA signature, the target genes were evaluated using the Kyoto Encyclopedia of Genes and Genomes (KEGG) signaling pathway. …”
Publicado 2022
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11270por Wang, Yimeng, Xu, Linling, Luo, Shuoming, Sun, Xiaoxiao, Li, Jiaqi, Pang, Haipeng, Zhou, Jun, Zhou, Yuemin, Shi, Xiajie, Li, Xia, Huang, Gan, Xie, Zhiguo, Zhou, Zhiguang“…Moreover, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses demonstrated that differentially methylated transcripts were involved in pathways related to immunity, including some closely associated with T1DM. …”
Publicado 2022
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11271por Sun, Chun-Yong, Yang, Le-Le, Zhao, Pan, Yan, Pei-Zheng, Li, Jia, Zhao, Dong-Sheng“…We used gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses to visualize associated functional pathways. …”
Publicado 2022
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11272por Lee, Anne H., Jha, Aashish R., Do, Sungho, Scarsella, Elisa, Shmalberg, Justin, Schauwecker, Amy, Steelman, Andrew J., Honaker, Ryan W., Swanson, Kelly S.“…In comparison with fiber-rich treatments that increased diversity and promoted Firmicutes and Bacteroidetes populations, resistant starch reduced microbial diversity and fecal pH, led to a bloom in Actinobacteria, and modified Kyoto Encyclopedia of Genes and Genomes orthology (KO) terms pertaining to starch and sucrose metabolism, fatty acid biosynthesis and metabolism, epithelial cell signaling, among others. …”
Publicado 2022
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11273“…Subsequently, the KEGG(Kyoto Encyclopedia of Genes and Genomes) pathways were performed to analyze the miRNA-mRNA pairs with negatively correlated miRNAs. …”
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11274Identification and Characterization of Sex-Biased miRNAs in the Golden Pompano (Trachinotus blochii)por Shi, Liping, Song, Feibiao, Zhang, Kaixi, Gu, Yue, Hu, Jinghan, Sun, Junlong, Wang, Zhongwei, Zhou, Li, Luo, Jian“…Gene ontology (GO) analysis confirmed that the TFIIA transcription factor complex (GO: 0005672) was the most significantly enriched GO term. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed that the differentially expressed miRNAs and target genes were mainly related to sex determination and gonadal developmental signaling pathways, specifically the Wnt signaling pathway, MAPK signaling pathway, and steroid biosynthetic pathway. …”
Publicado 2022
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11275por Ling, Xuebin, Wang, Jun, Qin, Xue, Lin, Chufen, Jie, Wei, Chen, Yane, Fu, Dajia, Yang, Yang, Meng, Qingwen, Lin, Jing, Liu, Hui, Li, Tianfa, Guo, Junli“…Gene set enrichment analysis was performed to evaluate TRPV channels expression levels and Kyoto Encyclopedia of Genes and Genomes (KEGG) mapping was used for pathway enrichment analysis. …”
Publicado 2022
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11276por Wu, Weibin, Chen, Ai, Lin, Siming, Wang, Qiuran, Lian, Guili, Luo, Li, Xie, Liangdi“…Then the DEGs were analyzed using a Weighted Gene Co-expression Network Analysis (WGCNA) and the key modules were determined, and to further explore their potential biological functions via Gene Ontology analysis (GO), Kyoto Encyclopedia of Genes and Genomes Pathway analysis (KEGG), and Gene Set Enrichment Analysis (GSEA). …”
Publicado 2022
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11277por Wang, Xianjue, Wei, Ping, Yang, Ling, Liu, Fangyuan, Tong, Xin, Yang, Xiaoyu, Su, Liya“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment results were processed by the database for annotation, visualization and integrated discovery. …”
Publicado 2022
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11278por Nie, Xin, Liu, Dawo, Zheng, Mingjun, Li, Xiao, Liu, Ouxuan, Guo, Qian, Zhu, Liancheng, Lin, Bei“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathways (KEGG) analysis showed that HERPUD1 and its related genes are enriched in regulating immunity, endoplasmic reticulum stress, ubiquitin-dependent degradation, ERS-induced apoptosis, and other key signaling pathways. …”
Publicado 2022
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11279“…METHOD: We compared differentially expressed genes (DEGs) and differentially methylated genes (DMGs) in gastric cancer and normal tissue samples using The Cancer Genome Atlas (TCGA) data. The Kyoto Encyclopedia of Gene and Genome (KEGG) and the Gene Ontology (GO) enrichment analysis' pathway annotations were conducted on DMGs and DEGs using a clusterProfiler R package to identify the important functions, as well as the biological processes and pathways involved. …”
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11280por Liu, Zhe, Zhang, Shuai, Zhu, Ying, Jing, Tianxing, Su, Honghua, Hu, Jin, Jiang, Xin, Yang, Yizhong“…(III) Gene Ontology (GO) enrichment analysis showed that the DEGs involved in “proteolysis”, “metabolic process”, “peptidase activity” and “structural molecule activity” were significantly enriched; Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that there were more DEGs in “Longevity regulating pathway-multiple species”, “Lysosome”, “Endocytosis”, “Spliceosome” and “Protein processing in endoplasmic reticulum”. …”
Publicado 2022
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