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11401por Du, Chong, Jiang, Jingbin, Zhang, He, Zhao, Tingting, Yang, Huanhuan, Zhang, Dongye, Zhao, Zhentong, Xu, Xiangyang, Li, Jingfu“…At 3 dpi, most DEGs were enriched in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways related to plant biotic responses, such as “plant-pathogen interaction” and “plant hormone signal transduction”. …”
Publicado 2020
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11402por Dong, Qianqian, Wang, Zishi, Jiang, Mengwan, Sun, Hong, Wang, Xuqin, Li, Yangwei, Zhang, Yifeng, Cheng, Han, Chai, Yurong, Shao, Tian, Shi, Luye, Wang, Zhenlong“…However, in the downregulated DEGs, GO terms of L. mandarinus were enriched in cell proliferation and protein transport and those of L. brandtii were enriched in nuclease and hydrolase activities, particularly in terms of developmental functions. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that upregulated DEGs in L. mandarinus were associated with DNA repair and damage prevention as well as angiogenesis and metastasis inhibition, whereas downregulated DEGs were associated with neuronal synaptic transmission and tumor-associated metabolic pathways. …”
Publicado 2020
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11403
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11404“…Enrichment analysis of Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) was performed by the DAVID online tool. …”
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11405“…Recent studies that identify enhancer regions by undertaking large scale functional genomic annotation of non-coding elements like Encyclopedia of DNA Elements (ENCODE) have begun to yield a better understanding of some complex diseases. …”
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11406por Li, Shenghua, Chen, Lan, Xu, Chen, Qu, Xiang, Qin, Zhenxiu, Gao, Jinggui, Li, Jinpin, Liu, Jingli“…The bioinformatic analysis of the host genes of differentially expressed (DE) circRNAs was performed by gene ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, KOBAS for pathway analysis and regulatory network analysis. miRNA-circRNA and miRNA-mRNA interactions were predicted by using TargetScan, miRanda and starBase. …”
Publicado 2020
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11407por Lu, Guan-Ming, Rong, Yong-Xian, Liang, Zhi-Jie, Hunag, Dong-Lin, Ma, Yan-Fei, Luo, Zhi-Zhai, Wu, Fang-Xiao, Liu, Xin-Heng, Liu, Yu, Mo, Steven, Qi, Zhong-Quan, Li, Hong-Mian“…To further explore the biological functions of the stemness-related genes, we performed Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. …”
Publicado 2020
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11408por Han, Lin, Wei, Xiu-Xiu, Zheng, Yu-Jiao, Zhang, Li-Li, Wang, Xin-Miao, Yang, Hao-Yu, Ma, Xu, Zhao, Lin-Hua, Tong, Xiao-Lin“…METHODS: In this study, a network pharmacology approach was employed, including drug-likeness evaluation, oral bioavailability prediction, protein‒protein interaction (PPI) network construction and analysis, Gene Ontology (GO) terms, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway annotation, and virtual docking, to predict the bioactive components, potential targets, and molecular mechanism of CDPF for COVID-19 treatment. …”
Publicado 2020
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11409“…Analysis of NSCLC cell lines from the Broad Institute Cancer Cell Encyclopedia and patients with NSCLC from The Cancer Genome Atlas dataset revealed significant co-occurrence of PPM1D/RBM38 and PPM1D/HIF1A mutations. …”
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11410por Tang, Jian, Gao, Hong, Liu, Yanqiu, Song, Jing, Feng, Yurong, Wang, Guilong, He, Youqin“…Based on Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) databases, we determined the mRNA targets associated with these miRNAs and studied the miRNA–mRNA interaction during the cardiovascular disease progression. …”
Publicado 2020
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11411por Choi, Da Hyeon, Oh, Se-Young, Choi, Ju Kwang, Lee, Kyeong Eun, Lee, Ju Yeon, Park, Yoon Jeong, Jo, Inho, Park, Yoon Shin“…The differentially expressed genes were classified into the Gene Ontology categories of cellular component (CC), functional component (FC), and biological process (BP) using KEGG (Kyoto encyclopedia of genes and genomes) pathway analysis. …”
Publicado 2020
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11412“…Then, the functional annotation of DEGs was carried out by Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis and Gene Ontology (GO) analysis. …”
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11413“…Further, the expression of 73, 78, and 71 miRNAs was upregulated in the ZT20/MCK0, ZT60/MCK0, and MCK1/MCK0 libraries, respectively. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed that most of the differentially expressed genes and miRNAs in the GL20/GL60 and ZT20/ZT60 libraries were involved in signal transduction. …”
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11414“…STRING database was applied to construct a protein–protein interplay (PPI) network, and Cytoscape software was used to visualize the miRNA-hub gene-Kyoto Encyclopedia of Genes and Genomes (KEGG) network. DE-miRNA expressions were evaluated by quantitative polymerase chain reaction (qPCR). …”
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11415por Song, Yunfei, Yang, Jianbo, Jing, Wenguang, Wang, Qi, Liu, Yue, Cheng, Xianlong, Ye, Fei, Tian, Jinying, Wei, Feng, Ma, Shuangcheng“…Thirdly, the key genes were used to find the biologic pathway and explain the therapeutic mechanism by genome ontology (GO) and kyoto encyclopedia of genes and genomes (KEGG) analysis. Lastly, the part of potential bioactive compounds were under enzyme activity inhibition tests. …”
Publicado 2020
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11416“…Proteomics technology identified 4915 proteins in the mouse livers, among which 71 proteins were differentially expressed. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that majority of the differentially expressed proteins were involved in the peroxisome and peroxisome proliferator-activated receptor signaling pathway, as well as biosynthesis of unsaturated fatty acids. …”
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11417“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis showed that DEMs were significantly enriched in cytokine–cytokine receptor interaction and functioned as the cellular responders to stress. …”
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11418por Li, Jun, Zhou, Yinyin, Zhou, Zihua, Lin, Chuanxu, Wei, Jinkuan, Qin, Yanpin, Xiang, Zhiming, Ma, Haitao, Zhang, Yang, Zhang, Yuehuan, Yu, Ziniu“…Among the annotated unigenes, 5091 and 7328 unigenes were assigned to Gene Ontology categories and the Kyoto Encyclopedia of Genes and Genomes (KEGG) Pathway database, respectively. …”
Publicado 2020
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11419por Chen, Zhiqiang, Lin, Tong, Liao, Xiaozhong, Li, Zeyun, Lin, Ruiting, Qi, Xiangjun, Chen, Guoming, Sun, Lingling, Lin, Lizhu“…With the Database for Annotation, Visualization, and Integrated Discovery (DAVID) server, the gene ontology (GO) biological processes and the Kyoto encyclopedia of genes and genomes (KEGG) signaling pathways of the targets enrichment were performed. …”
Publicado 2021
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11420por Han, Fuhui, Li, Jing, Zhao, Ranran, Liu, Lirong, Li, Lanlan, Li, Qian, He, Jianning, Liu, Nan“…We obtained target genes of differentially expressed lncRNAs (DELs) and performed enrichment analyses using Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG). We found that target mRNAs were enriched in metabolic processes and developmental pathways. …”
Publicado 2021
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