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1381por HAN, DONG-YAN, FU, DA, XI, HAO, LI, QIAN-YU, FENG, LI-JIN, ZHANG, WEI, JI, GUO, XIAO, JIA-CHENG, WEI, QING“…Further analysis with Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes demonstrated that the translation, nucleus assembly processes and molecular functions associated with vitamin B6 and pyridoxal phosphate binding in pancreatic carcinoma were abnormal. …”
Publicado 2015
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1382“…As an example, we extracted network fingerprints of 44 disease networks in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. The comparisons among the network fingerprints of disease networks revealed informative disease-disease and disease-signaling pathway associations, illustrating that the network fingerprinting framework will lead to new approaches for better understanding of biomedical networks.…”
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1383por Sakamoto, Mitsuo, Lapidus, Alla L., Han, James, Trong, Stephan, Haynes, Matthew, Reddy, T. B. K., Mikhailova, Natalia, Huntemann, Marcel, Pati, Amrita, Ivanova, Natalia N., Pukall, Rüdiger, Markowitz, Victor M., Woyke, Tanja, Klenk, Hans-Peter, Kyrpides, Nikos C., Ohkuma, Moriya“…The 3,621,509 bp long genome with its 3,059 protein-coding and 97 RNA genes is a part of the Genomic Encyclopedia of Type Strains, Phase I: the one thousand microbial genomes (KMG) project.…”
Publicado 2015
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1384“…By using Gene Ontology enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, the functional significance of the differentially expressed genes were analyzed. …”
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1385por Vogt, Carmen, Pernemalm, Maria, Kohonen, Pekka, Laurent, Sophie, Hultenby, Kjell, Vahter, Marie, Lehtiö, Janne, Toprak, Muhammet S., Fadeel, Bengt“…Notably, gene ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis revealed distinct protein corona compositions for the two different SPIONs. …”
Publicado 2015
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1386“…The proposed framework has been validated on genomics of drug sensitivity for cancer and cancer cell line encyclopedia database.…”
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1387por Reed, Spenser, Neuman, Hadar, Moscovich, Sharon, Glahn, Raymond P., Koren, Omry, Tako, Elad“…Through metagenomic analysis, we show that predicted Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways responsible for macro- and micronutrient uptake are significantly depleted under Zn deficiency; along with concomitant decreases in beneficial short chain fatty acids, such depletions may further preclude optimal host Zn availability. …”
Publicado 2015
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1388“…While several recent studies have used Google Trends as the leading online information source to answer corresponding research questions, we focus on the online encyclopedia Wikipedia often used for deeper topical reading. …”
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1389por Chen, Tingting, Zhang, Lei, Shang, Haihong, Liu, Shaodong, Peng, Jun, Gong, Wankui, Shi, Yuzhen, Zhang, Siping, Li, Junwen, Gong, Juwu, Ge, Qun, Liu, Aiying, Ma, Huijuan, Zhao, Xinhua, Yuan, Youlu“…On the basis of Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis, we concluded that the phenylalanine metabolism and starch and sucrose metabolism were active for energy homeostasis to cope with salt stress in cotton roots. …”
Publicado 2016
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1390“…Genes in the dominance category were functionally characterized using the Kyoto Encyclopedia of Genes and Genomes (KEGG) and the gene classifications offered by the Gene Ontology (GO) Consortium. …”
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1391por Safikhani, Zhaleh, El-Hachem, Nehme, Quevedo, Rene, Smirnov, Petr, Goldenberg, Anna, Juul Birkbak, Nicolai, Mason, Christopher, Hatzis, Christos, Shi, Leming, Aerts, Hugo JWL, Quackenbush, John, Haibe-Kains, Benjamin“…In 2013 we published an analysis demonstrating that drug response data and gene-drug associations reported in two independent large-scale pharmacogenomic screens, Genomics of Drug Sensitivity in Cancer (GDSC) and Cancer Cell Line Encyclopedia (CCLE), were inconsistent. The GDSC and CCLE investigators recently reported that their respective studies exhibit reasonable agreement and yield similar molecular predictors of drug response, seemingly contradicting our previous findings. …”
Publicado 2016
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1392“…INTRODUCTION: Encyclopedias are not a new platform for the distribution of knowledge, but they have recently drawn a great deal of attention in their online iteration. …”
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1393“…Annotation with reference to the Nr, Swiss-Prot and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases identified candidate-coding regions in 76,152 of these contigs, with transcripts for many enzymes in various metabolic pathways associated with secondary metabolite biosynthesis represented. …”
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1394por Li, Jing, Chen, Xiulan, Yi, Jiao, Liu, Yuchen, Li, Dameng, Wang, Jifeng, Hou, Dongxia, Jiang, Xiaohong, Zhang, Junfeng, Wang, Jin, Zen, Ke, Yang, Fuquan, Zhang, Chen-Yu, Zhang, Yujing“…In this study, we present the first comprehensive analysis of the protein, messenger RNA and microRNA profiles of 293T cell-derived exosomes; then, we characterized these data using Gene Ontology annotation and Kyoto Encyclopedia for Genes and Genomes pathway analysis. …”
Publicado 2016
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1395“…RNA-seq profiling indicated that 1,854 lncRNAs were differentially expressed (log2 fold change ≥ 1 or ≤−1, p < 0.05), in which 1,530 could potentially target 6,386 genes via cis-regulatory effects. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis for these target genes suggested that lncRNAs were involved in diverse pathways, such as lysosome, focal adhesion, and MAPK signaling. …”
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1396por Xing, Dongxu, Yang, Qiong, Jiang, Liang, Li, Qingrong, Xiao, Yang, Ye, Mingqiang, Xia, Qingyou“…DEGs and the enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of the two strains exhibited an obvious difference. …”
Publicado 2017
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1397“…We mapped 4,329 unigenes onto 317 pathways using the Kyoto Encyclopedia of Genes and Genomes Pathway database. Chitin metabolism unigenes were found in the transcriptome and the data indicated that a variety of enzymes was involved in chitin catabolic and biosynthetic pathways.…”
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1398“…Through this work, we can expand our encyclopedia of neural signatures to object recognition, and provide a broader understanding of quantitative neural responses to external stimuli. …”
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1399“…Many of the significant Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, including these differentially expressed proteins, were closely related to muscle growth, including apoptosis, thyroid hormone signaling, regulation of the actin cytoskeleton, and viral myocarditis (p < 0.05). …”
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1400“…Pathways were obtained from the database of Kyoto Encyclopedia of Genes and Genomes and Retrieval of Interacting Genes was used to download protein-protein interaction sets. …”
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