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1501“…Of these, 57 were upregulated and 69 were downregulated. Moreover, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that the most significant enriched KEGG term was “complement and coagulation cascades”. …”
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1502por Zhang, Min, Zhang, Hongyuan, Tan, Jie, Huang, Shuping, Chen, Xia, Jiang, Daohong, Xiao, Xueqiong“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analysis showed that these DEGs are mainly involved in the processes of response to stimulus, protein phosphorylation, hormone signal transduction, and plant-pathogen interaction pathways. …”
Publicado 2021
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1503
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1504“…Our study adopted a network pharmacology approach, focusing on the identification of active ingredients, drug target prediction, gene collection, gene ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment, and other network tools. …”
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1505por Wang, Yichu, Ni, Jinren, Yue, Yao, Li, Jiaye, Borthwick, Alistair G L, Cai, Ximing, Xue, An, Li, Li, Wang, Guangqian“…Here, we estimated the number of rivers in terms of stream-segmentation characteristics described by Horton, Strahler and Shreve stream-order rules, as well as their mixed mode for named rivers recorded in the Encyclopedia of Rivers and Lakes in China. As a result, the number of ‘vanishing rivers’ has been found to be highly relevant to statistical specifications in addition to the erroneous inclusion of pseudo-rivers primarily generated in arid or frost-thaw areas. …”
Publicado 2019
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1506
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1507“…Then, through the Kyoto Encyclopedia of Genome and Genome (KEGG) pathway and biological process (BP) analysis, we found that the upregulated and downregulated DEGs were abundant in different pathways, respectively. …”
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1508“…In total, 2462 differentially expressed genes were detected between the groups. Kyoto Encyclopedia of Genes and Genomes pathway analysis revealed downregulated activity of the hypoxia-inducible factor 1 alpha (HIF-1α) signaling pathway in EOMA cells following treatment with DHTS. …”
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1509por Ayagama, Thamali, Bose, Samuel J., Capel, Rebecca A., Priestman, David A., Berridge, Georgina, Fischer, Roman, Galione, Antony, Platt, Frances M., Kramer, Holger, Burton, Rebecca A.B.“…Density gradient fractions corresponding to tissue lysate; sarcoplasmic reticulum (SR), mitochondria (Mito) (1.3 g/mL); and EL with negligible contamination from SR or Mito (1.04 g/mL) were analyzed using Western blot, enzyme activity assay, and liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis (adapted discontinuous Percoll and sucrose differential density gradient). Kyoto Encyclopedia of Genes and Genomes, Reactome, Panther, and Gene Ontology pathway analysis showed good coverage of RAB proteins and lysosomal cathepsins (including cardiac-specific cathepsin D) in the purified EL fraction. …”
Publicado 2021
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1510por Sagara, Akiko, Nakata, Kohei, Matsumoto, Sokichi, Guan, Weiyu, Shinkawa, Tomohiko, Iwamoto, Chika, Ikenaga, Naoki, Ohuchida, Kenoki, Nakamura, Masafumi“…It was found that the ‘neuroactive ligand-receptor interaction’ pathway from the Kyoto Encyclopedia of Genes and Genomes pathway analysis was one of the altered pathways. …”
Publicado 2021
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1511“…Differential genes in high and low-risk groups revealed enrichment of many immune features by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. The degree of ferroptosis was negatively correlated with tumor mutational burden (i.e., the higher the degree of ferroptosis, the lower the tumor mutational burden). …”
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1512por Hong, Woo-Jong, Jiang, Xu, Choi, Seok-Hyun, Kim, Yu-Jin, Kim, Sun-Tae, Jeon, Jong-Seong, Jung, Ki-Hong“…This study identified 866 carbohydrate genes from the MapMan toolkit and the Kyoto Encyclopedia of Genes and Genomes database split into 11 clusters of different anatomical expression profiles. …”
Publicado 2021
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1513“…We also analyzed the expression of genes associated with acid-resistance mechanisms. Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis showed that the differentially expressed genes were enriched in ribosomes, citrate cycle, butanoate metabolism, oxidative phosphorylation, pentose phosphate, and the fatty acid biosynthetic pathways. …”
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1514por Kim, Sunje, Lee, Seong Eun, Yi, Shinae, Jun, Sangmi, Yi, Yoon-Sun, Nagar, Harsha, Kim, Cuk-Seong, Shin, Chungmin, Yeo, Min-Kyung, Kang, Yea Eun, Oh, Sang-Ha“…We identified the upregulation of mitochondrial oxidative stress response, protein processing in the endoplasmic reticulum, and TGF-β signaling in human keloid tissue samples compared to controls, based on ingenuity pathway and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. Electron microscopic examinations revealed an increased number of dysmorphic mitochondria and expanded endoplasmic reticulum (ER) in human keloid tissue samples than that in controls. …”
Publicado 2021
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1515por Pan, Min, Kohlbauer, Vera, Blancke Soares, Alexandra, Schinke, Henrik, Huang, Yuanchi, Kranz, Gisela, Quadt, Tanja, Hachmeister, Matthias, Gires, Olivier“…Potential interactors of EpCAM were identified in murine F9 teratoma cells using a stable isotope labeling with amino acids in cell culture-based proteomic approach (n = 77, enrichment factor >3, p value ≤ 0.05). Kyoto Encyclopedia of Genes and Genomes and gene ontology terms revealed interactions with regulators of endosomal trafficking and membrane recycling, which were further validated for Rab5, Rab7, and Rab11. …”
Publicado 2021
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1516por Pan, Ya, Chen, Wenjuan, Yan, Xiangyun, Yu, Boshi, Yao, Shuwen, Chen, Xiaohui, Han, Shuping“…Gene ontology and Kyoto Encyclopedia of Genes and Genomes pathway analyses were conducted, and circRNA-miRNA interaction networks were generated to predict the potential roles of circRNAs in NEC progression. …”
Publicado 2021
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1517por Feng, Huimin, Qiao, Kun, Wang, Chunchun, Chen, Bei, Xu, Min, Hao, Hua, Huang, Zhen, Liu, Zhiyu, Wang, Qin“…Gene ontology and the Kyoto Encyclopedia of Genes and Genomes analyses strongly suggest that cardiac muscle contraction and adrenergic signaling in cardiomyocyte pathways play an important role in TTX accumulation. …”
Publicado 2021
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1518“…Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were conducted to annotate the functions and pathways of recognized genes. …”
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1519por Ji, Yang, Lu, Xiaowen, Zhang, Huan, Luo, Dan, Zhang, Ailing, Sun, Min, Wu, Qing, Wang, Xiaoshan, Huang, Linkai“…A total of 1297, 2814, 7401, and 14,480 differentially expressed genes (DEGs) were found at 24 h, 48 h, 96 h, and 144 h, respectively. Based on Kyoto Encyclopedia of Genes and Genomes and Gene Ontology enrichment analyses, we found that many DEGs participated in plant hormone-related signaling pathways and the “oxidoreductase activity” pathway. …”
Publicado 2021
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1520“…Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses showed that these 661 DEGs were involved in multiple pathways such as signal transduction, reactive oxygen metabolism, and plant-pathogen interaction. …”
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