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AMÉRICA LATINA
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56701por Horlen, Kyle, Kaminskaya, Kristina, Yamaguchi, Alyson, Fung, Leonard C, Kennedy, Heather, Nguyen, Son, Dasari, Anvesh, Toledo Vo, April, Archana, Battiwala, Patel, Nidhi, Mohan, Deepa, Syed, Baber, Dhalla, Arvinder K, Imran, Mir, Hashim, Mir A“…Background: An orally administered robotic pill (RP) protects the drug from digestion during transit through the gastrointestinal tract before painlessly injecting the drug trans-enterically into the peritoneal space. Although parenteral, this unique delivery route can result in altered PK/PD profiles as drug absorption is primarily via mesenteric vasculature which drains into the portal vein. …”
Publicado 2023
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56702por Roth, Christian L, Shoemaker, Ashley H, Gottschalk, Michael, Miller, Jennifer, Yuan, Guojun, Malhotra, Sonali, Scimia, Cecilia, Jennifer Abuzzahab, M“…Here, we report changes in age-appropriate weight-related parameters after 6 months of treatment with setmelanotide in patients with HO who entered a long-term extension (LTE) trial. Methods: A Phase 2, multicenter, open-label study (NCT04725240) examined the efficacy and safety of 16-week setmelanotide treatment in patients aged ≥6 to ≤40 years with a clinical diagnosis of HO. …”
Publicado 2023
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56703por Balachandran, Neha, Wikswo, Mary, Boom, Julie A, Sahni, Leila C, Selvarangan, Rangaraj, Harrison, Christopher J, Halasa, Natasha B, Stewart, Laura S, Weinberg, Geoffrey A, Szilagyi, Peter G, Englund, Janet A, Klein, Eileen J, Staat, Mary A, Burrell, Allison, Williams, John V, Michaels, Marian G, Parashar, Umesh D, Mirza, Sara“…Stools were collected within 10 days of symptom onset and tested for enteric pathogens by validated molecular methods. …”
Publicado 2023
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56704por Zhu, Fengcai, Huang, Shoujie, Liu, Xiaohui, Chen, Qi, Zhuang, Chunlan, Zhao, Hui, Han, Jinle, Jaen, Anjuli May, Do, Thai Hung, Peter, Jonathan Grant, Dorado, Alexander Gonzalez, Tirador, Louie S, Zabat, Gelza Mae A, Villalobos, Ralph Elvi M, Gueco, Gemalyn Pineda, Botha, Lauren Livia Greta, Iglesias Pertuz, Shirley Patricia, Tan, Jiaxiang, Zhu, Kongxin, Quan, Jiali, Lin, Hongyan, Huang, Yue, Jia, Jizong, Chu, Xiafei, Chen, Junyu, Chen, Yixin, Zhang, Tianying, Su, Yingying, Li, Changgui, Ye, Xiangzhong, Wu, Ting, Zhang, Jun, Xia, Ningshao“…BACKGROUND: The live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing, China) confers long-lasting and broad protection in animal models and is, to our knowledge, the first COVID-19 mucosal vaccine to enter into human trials, but its efficacy is still unknown. …”
Publicado 2023
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56705por Joseph, Don R.“…However, the results permit the general statement that very small doses of adrenin on entering the circulation cause a fairly prolonged definite dilatation of a deganglionized pupil. …”
Publicado 1912
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56706“…In normal brain, glucose enters cells through GLUTs and is processed by glycolytic enzymes resulting in bioenergetic substrates such as pyruvate. …”
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56707por Bergin, Stephen P, Coles, Adrian, Calvert, Sara B, Farley, John, Santiago, Jonas, Zervos, Marcus J, Bardossy, Ana Cecilia, Kollef, Marin, Durkin, Michael J, Sims, Matthew, Greenshields, Claire, Kabchi, Badih A, Donnelly, Helen K, III, John Powers, Tenaerts, Pamela, Gu, Peidi, Fowler, Vance G, Holland, Thomas L“…APACHE II admission score >20 (P < 0.001, OR 2.14, 95% CI 2.00–2.29), admission diagnosis of trauma (P < 0.001, OR 3.31, 95% CI 1.90–5.74), frequent oral or lower respiratory tract suctioning (P < 0.001, OR 2.33, 95% CI 1.81–2.99), and receipt of enteral nutrition (P < 0.001, OR 2.31, 95% CI 1.69–3.16) were the key drivers of increased pneumonia risk. …”
Publicado 2018
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56708“…Our patient presented with severe dysphagia, which can be difficult to manage requiring enteral feeding. Video fluoroscopy was particularly useful in this case helping to stratify the severity of dysphagia and we would urge other clinicians to use this tool when investigating patients with suspected dermatomyositis to avoid potential complications of poor swallow including aspiration pneumonia. …”
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56709“…Patients cited the importance of data provenance so that patient-entered data Versus provider or electronic health record data could be easily differentiated. …”
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56710por Xie, Guoqiang, Zhang, Fan, Leung, Laura, Mooney, Michael A., Epprecht, Lorenz, Norton, Isaiah, Rathi, Yogesh, Kikinis, Ron, Al-Mefty, Ossama, Makris, Nikos, Golby, Alexandra J., O'Donnell, Lauren J“…False positive criteria included the presence of any fibers entering the temporal lobe, the inferior cerebellar peduncle, or the middle cerebellar peduncle. …”
Publicado 2020
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56711por Harpelunde Poulsen, K, Nielsen, J E, Frederiksen, H, Melau, C, Juul Hare, K, Langhoff Thuesen, L, Perlman, S, Lundvall, L, Mitchell, R T, Juul, A, Rajpert-De Meyts, E, Jørgensen, A“…Addition of exogenous FGF9 to the culture media resulted in a reduced number of germ cells entering meiosis in fetal ovaries (102 vs. 60 γH2AX(+) germ cells per mm(2), P < 0.05), while in fetal testes FGF9 stimulation resulted in an increased number of Sertoli cells (2503 vs. 3872 SOX9(+) cells per mm(2), P < 0.05). …”
Publicado 2019
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56712por Hassaniazad, Mehdi, Inchehsablagh, Behnaz Rahnama, Kamali, Hossein, Tousi, Abdolali, Eftekhar, Ebrahim, Jaafari, Mahmoud Reza, Fathalipour, Mohammad, Nikoofal-Sahlabadi, Sara, Gouklani, Hamed, Alizade, Hesam, Nikpoor, Amin Reza“…Finally, according to the order in which patients enter the study, packages are given to patients based on their number. …”
Publicado 2020
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56713por Rekdal, Vayu Maini, Bess, Elizabeth N., Bisanz, Jordan E., Turnbaugh, Peter J., Balskus, Emily P.“…To be effective, L-dopa must enter the brain and be converted to the neurotransmitter dopamine by the human enzyme aromatic amino acid decarboxylase (AADC). …”
Publicado 2019
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56714por Eron, Joseph J, Wilkin, Aimee, Ramgopal, Moti, Osiyemi, Olayemi, McKellar, Mehri, McKellar, Mehri, Slim, Jihad, Asmuth, David, DeJesus, Edwin, German, Polina, Blair, Christiana, Carter, Christoph C, Brainard, Diana M, Collins, Sean E, Martin, Hal“…RESULTS: 55 enrolled, 36 completed E/C/F/TAF, 10 entered the B/F/TAF extension. The median age was 55 yrs (range 34-63); median time on HD was 4 yrs (range 2-16). …”
Publicado 2020
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56715“…Ms LL is an 84 year old woman with a lengthy history of Histrionic and Narcissistic traits who was followed for many years by a provider who retired in the month prior to COVID-19 quarantine restrictions. She entered treatment with a written list of demands for multiple controlled substances in 90 day quantities in order to "stock up" for the pandemic. …”
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56716por Askari, Gholamreza, Alikiaii, Babak, Soleimani, Davood, Sahebkar, Amirhossein, Mirjalili, Mahdiye, Feizi, Awat, Iraj, Bijan, Bagherniya, Mohammad“…Capsules will be administered after oral or enteral feeding at 9, 15 and 21 o’clock. MAIN OUTCOMES: The primary outcome is the time from initiation of supplementation (curcumin-piperine or placebo) to normalization of fever, respiratory rate, and blood oxygen saturation. …”
Publicado 2021
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56717por Cranmer, Holly, Podkonjak, Tanja, Benson, Eugene, Dabora, Jonathon, Jackson, Graham H“…Methods: A decision tree model was developed in Microsoft Excel® (Figure 1). Patients enter the model and are assigned a probability of being treated; those that are treated are then assigned a probability of IV, SC or oral-based therapy. …”
Publicado 2020
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56718por Kucia, Magdalena, Bujko, Kamila, Ciechanowicz, Andrzej, Cymer, Monika, Sielatycka, Katarzyna, Ratajczak, Janina, Ratajczak, Mariusz Z“…It is well established that SARS-CoV-2 enters human cells after binding to the angiotensin-converting enzyme 2 (ACE2) receptor and utilizes a spike protein (S) for attachment and entry into the cells, leading to their lysis or damage. …”
Publicado 2020
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56719por Paul, Sonal, Patel, Nisha, Kumarasinghe, Chathula, Nimkar, Neil, Singh, Angelica, Vishnuvardhan, Nivetha, Ashraf, Farah, Mazloom, Anita, Kodama, Rich, Kalsi, Amardeep, Usta, Soeb, Ashfaq, Abeer, Gregos, Peter, Khan, Uqba, Weingarten, Jeremy, Patel, Eshan“…Baseline patient characteristics and outcomes were entered manually by medical professionals via chart review using the electronic medical record (EMR). …”
Publicado 2020
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56720por De Luna, Gonzalo, Lemonier, Nicolas, Aidan, Alexis, Bontemps, Lea, Hautefaye, Manuel, Diakonoff, Hadrien, Aubrun, Cecile, Pham Hung D'Alexandry D'Orengiani, Anne-Laure, Bachir, Dora, Driss, Françoise, Jebali, Amna, Habibi, Anoosha, Bartolucci, Pablo“…With the ongoing situation, our delocalized hospitalization system has proven interesting enough to enter a new phase: DREPADOM was selected as part of a public call for tenders, for financial support to make the structure permanent (DREPADOM - APRES). …”
Publicado 2020
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