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  1. 56701
    “…Background: An orally administered robotic pill (RP) protects the drug from digestion during transit through the gastrointestinal tract before painlessly injecting the drug trans-enterically into the peritoneal space. Although parenteral, this unique delivery route can result in altered PK/PD profiles as drug absorption is primarily via mesenteric vasculature which drains into the portal vein. …”
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  2. 56702
    “…Here, we report changes in age-appropriate weight-related parameters after 6 months of treatment with setmelanotide in patients with HO who entered a long-term extension (LTE) trial. Methods: A Phase 2, multicenter, open-label study (NCT04725240) examined the efficacy and safety of 16-week setmelanotide treatment in patients aged ≥6 to ≤40 years with a clinical diagnosis of HO. …”
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  3. 56703
  4. 56704
    “…BACKGROUND: The live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine (dNS1-RBD, Pneucolin; Beijing Wantai Biological Pharmacy Enterprise, Beijing, China) confers long-lasting and broad protection in animal models and is, to our knowledge, the first COVID-19 mucosal vaccine to enter into human trials, but its efficacy is still unknown. …”
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  5. 56705
    por Joseph, Don R.
    Publicado 1912
    “…However, the results permit the general statement that very small doses of adrenin on entering the circulation cause a fairly prolonged definite dilatation of a deganglionized pupil. …”
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  6. 56706
    “…In normal brain, glucose enters cells through GLUTs and is processed by glycolytic enzymes resulting in bioenergetic substrates such as pyruvate. …”
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  7. 56707
    “…APACHE II admission score >20 (P < 0.001, OR 2.14, 95% CI 2.00–2.29), admission diagnosis of trauma (P < 0.001, OR 3.31, 95% CI 1.90–5.74), frequent oral or lower respiratory tract suctioning (P < 0.001, OR 2.33, 95% CI 1.81–2.99), and receipt of enteral nutrition (P < 0.001, OR 2.31, 95% CI 1.69–3.16) were the key drivers of increased pneumonia risk. …”
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  8. 56708
    “…Our patient presented with severe dysphagia, which can be difficult to manage requiring enteral feeding. Video fluoroscopy was particularly useful in this case helping to stratify the severity of dysphagia and we would urge other clinicians to use this tool when investigating patients with suspected dermatomyositis to avoid potential complications of poor swallow including aspiration pneumonia. …”
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  9. 56709
    “…Patients cited the importance of data provenance so that patient-entered data Versus provider or electronic health record data could be easily differentiated. …”
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  10. 56710
  11. 56711
    “…Addition of exogenous FGF9 to the culture media resulted in a reduced number of germ cells entering meiosis in fetal ovaries (102 vs. 60 γH2AX(+) germ cells per mm(2), P < 0.05), while in fetal testes FGF9 stimulation resulted in an increased number of Sertoli cells (2503 vs. 3872 SOX9(+) cells per mm(2), P < 0.05). …”
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  12. 56712
  13. 56713
    “…To be effective, L-dopa must enter the brain and be converted to the neurotransmitter dopamine by the human enzyme aromatic amino acid decarboxylase (AADC). …”
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  14. 56714
  15. 56715
    por Lantz, Melinda, Blissett, Kecia-ann
    Publicado 2021
    “…Ms LL is an 84 year old woman with a lengthy history of Histrionic and Narcissistic traits who was followed for many years by a provider who retired in the month prior to COVID-19 quarantine restrictions. She entered treatment with a written list of demands for multiple controlled substances in 90 day quantities in order to "stock up" for the pandemic. …”
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  16. 56716
    “…Capsules will be administered after oral or enteral feeding at 9, 15 and 21 o’clock. MAIN OUTCOMES: The primary outcome is the time from initiation of supplementation (curcumin-piperine or placebo) to normalization of fever, respiratory rate, and blood oxygen saturation. …”
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  17. 56717
    “…Methods: A decision tree model was developed in Microsoft Excel® (Figure 1). Patients enter the model and are assigned a probability of being treated; those that are treated are then assigned a probability of IV, SC or oral-based therapy. …”
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  18. 56718
    “…It is well established that SARS-CoV-2 enters human cells after binding to the angiotensin-converting enzyme 2 (ACE2) receptor and utilizes a spike protein (S) for attachment and entry into the cells, leading to their lysis or damage. …”
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  19. 56719
    “…Baseline patient characteristics and outcomes were entered manually by medical professionals via chart review using the electronic medical record (EMR). …”
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  20. 56720
    “…With the ongoing situation, our delocalized hospitalization system has proven interesting enough to enter a new phase: DREPADOM was selected as part of a public call for tenders, for financial support to make the structure permanent (DREPADOM - APRES). …”
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