“…BACKGROUND: Humans ingest a multitude of smallmolecules that are foreign to the body (xenobiotics), including dietary components, environmental chemicals, and pharmaceuticals. The trillions of microorganisms that inhabit our gastrointestinal tract (the human gut microbiota) can directly alter the chemical structures of such compounds, thus modifying their lifetimes, bioavailabilities, and biological effects. …”
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“…With 70% of youth experiencing exposure to environmental traumatic stressors, the above study stresses the significance of early screening of trauma-related events in psychiatric patients. …”
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“…Other parameters include: genetic and epigenetic vulnerability; transgenerational actions; environmental influences in the management of early life stress; the nature, severity, and duration of the traumatic event; the developmental stage, age at the time of trauma; and comorbidities (Pervanidou, 2008). …”
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“…Distinct genetic background exists and other environmental or genetic factor(s) may contribute to MMD. …”
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“…Even though microalgal lipid production under optimal environmental factors has been reported by some researchers, the light/dark cycle and temperature are regarded as separate parameters in their studies. …”
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“…Thus, multi-pronged inter-sectoral strategies that holistically address the environmental and structural roots of child cognitive impairment and educational loss in the developing world may be needed to fully realize the benefit of mass deworming programs.…”
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“…An increase of 8.9 cm in adult height over mean parental height is estimated to occur in the cohort from low-middle income countries, provided that children continue to have adequate health, environmental, and nutritional conditions. CONCLUSION: The cohort enrolled in the INTERGROWTH-21(st) standards remained healthy with adequate growth and motor development up to 2 years of age, which supports its appropriateness for the construction of international fetal and preterm postnatal growth standards.…”
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“…METHODS AND FINDINGS: The Environmental Determinants of Diabetes in the Young (TEDDY) study followed genetically at-risk children at 3- to 6-monthly intervals from birth for the development of islet autoantibodies and type 1 diabetes. …”
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“…Adversity in early life has been associated with psychotic symptoms, and low socioeconomic status (SES) is an established environmental risk factor for several mental disorders. …”
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“…Historical models propose that distinct classes of individuals expressing different forms of schizotypy may represent manifestations of differential levels of genetic and environmental risk for schizophrenia (or related illness). …”
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“…However, while an increasing number of studies have investigated how environmental risk factors for affective and non-affective psychosis map onto symptom dimensions, only a few have examined these dimensions in relation to genetic variants as summarised by Polygenic Risk Score (PRS). …”
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“…In contrast, disturbances that emerge during late adolescence and early adulthood (e.g., via abnormal neuromaturational events and/or environmental factors) could help to explain cases with normal premorbid psychological health and a more acute onset of psychotic symptoms and functional impairment in the late teens and early twenties. …”
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“…RESULTS: We found that, compared to individuals with neither affective disturbances nor PEs, JTC bias was more likely to be present in individuals with co-occurring affective disturbances, PEs, and HS (moderate psychosis [1–2 PEs]: relative risk ratio [RRR]=1.23, 95% CI 1.03 – 1.48, p=0.023; high psychosis [3 or more PEs or HS]: RRR=1.66, 95% CI 1.26 – 2.19, p<0.001) in models adjusted for socio-demographic characteristics and socio-environmental factors. However, when we additionally adjusted for working memory performance this association was attenuated (moderate psychosis: RRR=1.17, 95% CI 0.98 – 1.41, p=0.088; high psychosis: RRR=1.57, 95% CI 1.19 – 2.08, p=0.002). …”
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“…Included religions were determined through an environmental scan, Australian population statistics, and documentary analysis of project steering committee meeting minutes. …”
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“…BACKGROUND: Lead (Pb(2+)) is an environmental neurotoxicant that disrupts neurodevelopment, communication, and organization through competition with Ca(2+) signaling. …”
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“…We demonstrate that aging, frequent exposures to environmental hazards, infections and pathogen-specific vaccines and ingredients are ‘antigen overload’ for immune system, skewing the Yin and Yang response profiles and leading to induction of ‘mild’, ‘moderate’ or ‘severe’ immune disorders. …”
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“…METHODS AND FINDINGS: We used a modeling system that included downscaling historical and future climate data with the Weather Research and Forecasting (WRF) model, simulating building electricity demand using the Regional Building Energy Simulation System (RBESS), simulating power sector production and emissions using MyPower, simulating ambient air quality using the Community Multiscale Air Quality (CMAQ) model, and calculating the incidence of adverse health outcomes using the Environmental Benefits Mapping and Analysis Program (BenMAP). …”
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“…We also evaluated the United States Environmental Protection Agency (EPA)’s Air Quality Index (AQI) with this conditional logistic regression method. …”
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“…There is urgent need for a formal nomenclature of sequence-based, voucherless Fungi, given that environmental sequencing has accumulated more than one billion fungal ITS reads in the Sequence Read Archive, about 1,000 times as many as fungal ITS sequences in GenBank. …”
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“…General observations were made on environmental sanitation in the schools. The location of each school was geo-referenced using a GPS machine (Garmin(®)GPSMAP62, Garmin Ltd, Southampton, UK). …”
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