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276901por Edelman, Steven Victor, Conoscenti, Valentina, Junaidi, M Khaled, Close, Nicole, Sequeira, David, Nguyen, Anh“…XP-3924 also exhibited a favorable PK and PD profile and may be a viable alternative to insulin and pramlintide co-administration to improve treatment adherence and overall glycemic control, especially after meals, addressing an unmet need in the clinical care of people with type 1 diabetes.…”
Publicado 2021
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276902por Comim, Fabio Vasconcellos, Mujica, Lady Katerine Serrano, Valente, Fernanda, Miyazato, Ligia G, Manta, Manuela W, Amaral, Carolina D, Premaor, Melissa O, Macari, Soraia, Silva, Tarcilia, Barrioni, Breno R, Carlos, Bruna L, Silva, Guilherme J A, Shimano, Antonio Carlos, Antoniazzi, Alfredo Q“…Our results suggest that androgenization in a rodent model of PCOS leads, at the same time, to a generalized increase in trabecular (cancellous) bone mass (especially in the spine), associated with a reduced cortical bone mass and decreased strength of the femur.…”
Publicado 2021
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276903por Daniello, Lea, Elshiaty, Mariam, Bozorgmehr, Farastuk, Kuon, Jonas, Kazdal, Daniel, Schindler, Hannah, Shah, Rajiv, Volckmar, Anna-Lena, Lusky, Fabienne, Diekmann, Leonore, Liersch, Stephan, Faehling, Martin, Muley, Thomas, Kriegsmann, Mark, Benesova, Karolina, Stenzinger, Albrecht, Thomas, Michael, Christopoulos, Petros“…Despite more frequent occurrence with PD-L1 positive tumors, lower NLR, and better ECOG PS, irAEs are independently associated with longer survival, especially when affecting the skin. Lethality is below 1%.…”
Publicado 2021
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276904Publicado 2021“…CONCLUSION: The expression and coexpression of BCL6 negative, P53 positive and BCL2(S +) have certain value in the prognostic evaluation of DLBCL, especially in the group of age≤60-year-old and IPI score 0–2.…”
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276905por Paradissis, Chariclia, Cottrell, Neil, Coombes, Ian, Scott, Ian, Wang, William, Barras, Michael“…. • Health professionals need to carefully prescribe and frequently review cardiovascular medications, especially in older adults. • Patient and health professional discussions should be based on both the benefits and harms of cardiovascular medications. • Cardiovascular medications should be included in all ‘high risk’ medication guidelines.…”
Publicado 2021
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276906por Marche, Benedikt, Neuwirth, Meike, Kugler, Christiane, Bouillon, Bertil, Mattner, Frauke, Otchwemah, Robin“…BACKGROUND: Prevention of hospital-acquired infections, in the clinical field of orthopedics and traumatology especially surgical site infections, is one of the major concerns of patients and physicians alike. …”
Publicado 2020
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276907por Schubert, Manuel, Awan, Tariq, Sciascia, Aaron, Pacheco, Emily, DeMink, Jennifer, Selak, David, Snyder, Corey, Gagnier, Joel, Freehill, Michael“…Pitch count limits have been instituted in an attempt to help curtail this rise in throwing injuries, especially in youth athletes. In order to provide more objective data regarding current pitch count limits for youth pitchers, the purpose of this pilot study was to evaluate for potential fatigue of the flexor-pronator mass by assessing changes in medial elbow laxity, noninvasively characterizing changes in muscle glycogen storage within the forearm flexor-pronator mass, and evaluating changes in subjective fatigue, strength, range of motion (ROM), pitching velocity, and accuracy with increasing number of pitches thrown by 10-year-old pitchers up to their recommended 75 pitch count limit. …”
Publicado 2021
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276908por Fan, Bo, Mohammed, Alradhi, Huang, Yuanbin, Luo, Hong, Zhang, Hongxian, Tao, Shenghua, Xu, Weijiao, Liu, Qian, He, Tao, Jin, Huidan, Sun, Mengfan, Sun, Man, Yun, Zhifei, Zhao, Rui, Wu, Guoyu, Li, Xiancheng“…Existing studies focusing on Chinese populations are relatively rare, especially for Northeast China. Meanwhile, relevant studies on the effects of aspirin on the occurrence or prognosis of BCa are inconsistent or even controversial. …”
Publicado 2021
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276909por Tailor, Imran K, Altaf, Syed Y, Alshehry, Nawal F, Alser, Alaa M, Marei, Mohammed, Alfayez, Mansour, Motabi, Ibraheem, Zaidi, Syed Ziauddin A“…There is paucity of data on the outcomes of patients with autologous stem cell transplant and concurrent COVID-19 infections, especially from eastern mediterranean region, no similar studies have been reported so far. …”
Publicado 2020
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276910“…There is little clinical experience of COVID‐19 patients with sickle cell disease (SCD) especially in our country, and most reported cases presented with acute chest syndrome (ACS). …”
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276911por Zhai, Zhen, Ruan, Jian, Zheng, Yi, Xiang, Dong, Li, Na, Hu, Jingjing, Shen, Jianfei, Deng, Yujiao, Yao, Jia, Zhao, Peng, Wang, Shuqian, Yang, Si, Zhou, Linghui, Wu, Ying, Xu, Peng, Lyu, Lijuan, Lyu, Jun, Bergan, Raymond, Chen, Tianhui, Dai, Zhijun“…CONCLUSIONS AND RELEVANCE: This cross-sectional study found that incident cases of mesothelioma and deaths associated with mesothelioma continuously increased worldwide, especially in resource-limited regions with low SDI levels. …”
Publicado 2021
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276912“…BACKGROUND: COVID-19 preventive perceptions and behaviors, especially among US millennials, are an important means by which the pandemic can be slowed and negative health outcomes can be averted. …”
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276913por Presbitero, Alva, Melnikov, Valentin R., Krzhizhanovskaya, Valeria V., Sloot, Peter M. A.“…This poses significant risks to health especially to those with limited access to cooling infrastructures. …”
Publicado 2021
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276914por Gabor, Lisa, Gowthaman, Divya, Gressel, Gregory, Kuo, Dennis Yi-Shin, Nevadunsky, Nicole, Bansal, Nisha“…OBJECTIVES: COVID-19 is characterized by rapid human-to-human transmission via contaminated respiratory droplets and therefore presents unique challenges in all aspects of healthcare delivery. This is especially true for patients with conditions, such as gynecologic cancer, which require frequent interface with healthcare centers. …”
Publicado 2021
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276915por Eggenhuizen, Geerke M, Go, Attie, Koster, Maria P H, Baart, Esther B, Galjaard, Robert Jan“…WIDER IMPLICATIONS: Based on the literature, the advice to clinicians is to monitor fetal growth intensively from first trimester onwards in case of CPM, especially when chromosome 2, 3, 7, 13, 15, 16 and 22 are involved. …”
Publicado 2021
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276916por Kojima, Waka, Yamano, Koji, Kosako, Hidetaka, Imai, Kenichiro, Kikuchi, Reika, Tanaka, Keiji, Matsuda, Noriyuki“…This process is complex, especially in mammals, with many regulatory factors. …”
Publicado 2021
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276917por Sun, Xiaoge, Wang, Yue, Wang, Erdan, Zhang, Shu, Wang, Qianqian, Zhang, Yan, Wang, Yajing, Cao, Zhijun, Yang, Hongjian, Wang, Wei, Li, Shengli“…The cows, during the high-yielding period, are especially susceptible to metabolic diseases such as digestive alterations, rumen acidosis, and lameness. …”
Publicado 2021
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276918“…BACKGROUND: The COVID-19 pandemic has created an urgent need to rapidly disseminate health information, especially to those with cancer, because they face higher morbidity and mortality rates. …”
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276919por Tan, Jiarong, Hu, Chengping, Deng, Pengbo, Wan, Rongjun, Cao, Liming, Li, Min, Yang, Huaping, Gu, Qihua, An, Jian, Jiang, Juan“…Concurrent 19del/L858R and tumor-suppressor gene alterations, especially TP53, can be established as prognostic biomarkers.…”
Publicado 2021
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276920por Machado, Isidro, Nieto Morales, María Gema, Cruz, Julia, Lavernia, Javier, Giner, Francisco, Navarro, Samuel, Ferrandez, Antonio, Llombart-Bosch, Antonio“…The inclusion of molecular findings in risk stratification systems could improve the precision in the classification of SFTs, especially those of intermediate risk. Future studies will be required to determine the most effective way to incorporate molecular analyses into RSS on SFTs. …”
Publicado 2021
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