“…. • Blocking this receptor, especially in specific brain regions such as nerve cells of the amygdala, bed nucleus of stria terminalis, and hippocampus, produced the anxiety reduction seen during agomelatine treatment. • Agomelatine also activates the melatonin (MT) receptor, which is known to keep anxiety in check, promote sleep, and maintain the sleep cycle. • Agomelatine should thus tackle sleep disturbances commonly seen in patients with GAD. • Beyond 5-HT(2C) and MT receptors, signalling molecules in nerve cells that are known to be involved in anxiety disorders (called ‘neurotransmitters’ and ‘neuropeptides’) are also affected by agomelatine. …”
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“…Whereas eGFR often underestimates GFR, especially in healthy donors, measured GFR (mGFR) allows more precise kidney function assessment, and therefore holds potential to increase the living donor pool. …”
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“…It is not clear how to realize the development mechanism of digital agriculture, especially in the context of intelligent agriculture. …”
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“…Palliative care is necessary in chronic non-oncologic diseases, especially in multipathologic and symptom-intensive patients. …”
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“…In contrast, the MSKCC cohort showed that CCND1 amplification was an unfavorable prognostic factor for patients with melanoma, especially for patients who received ICIs and had a high tumor mutation burden (TMB). …”
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“…Measuring local haemodynamics in skeletal muscle has the potential to provide valuable insight into the oxygen delivery to tissue, especially during high demand situations such as exercise. …”
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“…In light of the COVID-19 pandemic and the movement toward web-based and hybrid clinic visits and meetings, it has become especially salient to assess phone ownership among individuals with substance use disorders and their comfort in navigating phone functionality and using phones for mental health purposes. …”
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“…SIMPLE SUMMARY: Corvids (e.g., crows, magpies and jays) are an important part of urban settlements, especially during winter. To understand the factors affecting the long-term population trends of corvids, we counted wintering corvids in 31 human settlements along a 920 km latitudinal gradient in Finland during four winters between 1991 and 2020. …”
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“…The milk contained an elevated level of linoleic acids (LA), n-3 FA, and especially alpha-linolenic acids (ALA), while the n-6:n-3 ratio declined using hemp oil. …”
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“…OBJECTIVES: The diagnosis and treatment of distal tibiofibular syndesmosis (DTFS) injury can be challenging, especially in cases of subtle instability that may be masked on two-dimensional conventional radiographs. …”
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“…CONCLUSIONS: BHMR is more often performed in younger, lower BMI individuals especially during a concomitant ACL reconstruction. …”
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“…Transverse and z-type fractures may require increased vigilance, especially among obese patients, with potential consideration for dual plating in these circumstances.…”
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“…As a result, Li(2)CO(3), which is one of the lithium compounds, and has become an important contaminant in the environment with increasing technological developments, caused a combined and versatile toxicity in Allium cepa L. meristematic cells, especially by causing deterioration in antioxidant/oxidant dynamics.…”
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“…Thus, there exists a need to utilize social media platforms, like Twitter, to help augment preparedness, especially at the intersection between oncology and COVID-19, where tweets could help hint at potential biomolecular interactions. …”
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“…Airborne lidar that directly senses variation in vegetation height and density has proven to be especially useful for landscape-scale fuel load and consumption mapping. …”
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“…However, nutritional interventions are indispensable for the long-term wellbeing of patients, especially for those with dysphagia in whom an indwelling gastric tube is the most viable method of providing enteral nutrition. …”
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“…The findings of our study may help direct policymaking for expanding the use of virtual clinics, especially in countries struggling with the development and promotion of telemedicine virtual clinic services.…”
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“…BACKGROUND: Understanding how individuals think about a topic, known as the mental model, can significantly improve communication, especially in the medical domain where emotions and implications are high. …”
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“…Studies have shown that PFCs are hepatotoxic, embryotoxic, reproductive-toxic, neurotoxic, and carcinogenic, and can interfere with the endocrine system, change animal instinct behavior, and potentially induce developmental neurotoxicity in humans, especially in young children. However, there are few established methods for the simultaneous detection of multiple PFC precursors, necessitating the same particularly for textiles. …”
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“…Due to their potential low allergenicity, these milk powders have become a substitute for breast milk, especially for infants, and for people with lactose intolerance. …”
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