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277681por Rosen, Marlene, Kaiser, Nathalie, Betz, Linda, Haidl, Theresa, Seves, Mauro, Pilgram, Tanja, Schultze-Lutter, Frauke, Chisholm, Katharine, Bertolino, Alessandro, Borgwardt, Stefan, Brambilla, Paolo, Lencer, Rebekka, Meisenzahl, Eva, Ruhrmann, Stephan, Salokangas, Raimo K R, Upthegrove, Rachel, Wood, Stephen, Koutsouleris, Nikolaos, Kambeitz, Joseph“…DISCUSSION: Results suggest that especially prediction of the multi-faceted construct of role functioning could benefit from inclusion of a rich set of clinical variables. …”
Publicado 2020
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277682por Mollon, Josephine, Knowles, Emma, Mathias, Samuel, Rodrigue, Amanda, Koenis, Marinka, Pearlson, Godfrey, Glahn, David“…DISCUSSION: Individuals with psychotic disorders, especially affective psychoses, experienced more childhood and adult trauma than controls, and also individuals with non-psychotic psychiatric disorders. …”
Publicado 2020
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277683“…BACKGROUND: It is becoming increasingly clear that longer duration of untreated psychosis (DUP) is associated with adverse clinical outcomes in patients with psychosis spectrum disorders. Especially because this association is often cited when justifying early intervention efforts, it is imperative to better understand underlying biological mechanisms. …”
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277684por Hird, Emily, Allen, Paul, Orlov, Natasza, Modinos, Gemma, Bossong, Matthijs, Antoniades, Mathilde, Sampson, Carly, Azis, Matilda, Howes, Oliver, Stone, James, Grace, Antony, McGuire, Philip“…DISCUSSION: Whilst hippocampal glutamate metabolite levels are associated with altered hippocampal activity in CHR individuals - especially in those who later transition to psychosis - hippocampal glutamate metabolite levels do not modulate connectivity between the hippocampus and striatum. …”
Publicado 2020
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277685por Klauser, Paul, Klauser, Antoine, Cleusix, Martine, Ledoux, Jean-Baptiste, von Plessen, Kerstin, Lazeyras, Francois, Hagmann, Patric, Conus, Philipp, Solida, Alessandra, Do, Kim“…Alterations of gross brain anatomy are relatively late events but early and subtle neurochemical changes and especially those reflecting oxidative stress and concomitant synaptic remodeling are promising candidates. …”
Publicado 2020
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277686por Ilzarbe, Daniel, Baeza, Inmaculada, De la Serna, Elena, Rosa, Mireia, Puig-Navarro, Olga, Masias, Mireia, Pariente, Jose, Fortea, Adriana, Batalla, Albert, Bossong, Matthijs, Castro-Fornieles, Josefina, Sugranyes, Gisela“…BACKGROUND: Functional connectivity (FC) during the resting-state is reduced in schizophrenia, especially within the Default Mode Network (DMN) (Dong 2018), and between the hippocampus, striatum and ventral tegmental area (VTA), which together conform a Midbrain Network (Gangadin 2019). …”
Publicado 2020
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277687por Belangero, Sintia, Navarro, Gabrielle, Fonseca, Lais, Leite Santoro, Marcos, Oliveira, Adrielle, Spindola, Leticia, Pan, Pedro, Bressan, Rodrigo, Gadelha, Ary“…The persistence and accumulation of psychosocial problems are also well established risk factors, but how they interplay with genetic risk is still unclear, especially during developmental stages. Polygenic risk score to schizophrenia (PRS-SZ) and the polyenviromic risk score (PERS) are two validated measures created to assess the contribution of each factor on the development of such psychopathology. …”
Publicado 2020
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277688por Chu, Min-yi, Lui, Simon S Y, Hung, Karen S Y, Sham, P C, Mak, Henry K F, Cheung, Eric F C, Chan, Raymond C K“…However, previous studies assessing PV in schizophrenia spectrum disorders, especially in ultra-high risk individuals, were confounding. …”
Publicado 2020
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277689por Wang, Yi, Pu, Cheng-cheng, Zhang, Yi-jing, Cai, Xin-lu, Liang, Yun-si, Zhou, Shu-zhe, Ma, Yan-tao, Yu, Xin, Chan, Raymond C K“…DISCUSSION: Our findings showed reduced cerebellar grey matter volumes and the abnormal age-related changes of cerebellum in SCZ patients, especially in the regions related to frontoparietal network and cognitive function. …”
Publicado 2020
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277690por Pillinger, Toby, McCutcheon, Rob, Efthimiou, Orestis, Cipriani, Andrea, Howes, Oliver“…Considering the increased prevalence of metabolic syndrome, cardiovascular disease, and cardiovascular mortality in schizophrenia, these data may be used to inform antipsychotic-prescribing, especially in those at-risk groups we have identified. …”
Publicado 2020
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277691“…Since high mortality rates from sepsis induced DIC due to COVID-19 infection has also been associated with thrombotic events and elevated levels of D-dimer, randomized controlled trials of using anticoagulant therapy with heparin is urgently required. This is especially important in patients on ventilators who have met certain sepsis induced coagulopathy (SIC) criteria. …”
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277692por Celik, Eren, Baus, Wolfgang, Baues, Christian, Schröder, Wolfgang, Clivio, Alessandro, Fogliata, Antonella, Scorsetti, Marta, Marnitz, Simone, Cozzi, Luca“…Concerning the organs at risk, the IMPT plans showed a systematic and statistically significant incremental sparing when compared to RA_RP, especially for the heart. The mean dose to the combined lungs was 8.6 ± 2.9 Gy for RA_RP, 3.2 ± 1.5 Gy and 2.9 ± 1.2 Gy for IMPT_2F and IMPT_3F. …”
Publicado 2020
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277693por Rizos, Christos V., Florentin, Matilda, Skoumas, Ioannis, Tziomalos, Konstantinos, Rallidis, Loukianos, Kotsis, Vasileios, Athyros, Vasileios, Skalidis, Emmanouil, Kolovou, Genovefa, Garoufi, Anastasia, Bilianou, Eleni, Koutagiar, Iosif, Agapakis, Dimitrios, Kiouri, Estela, Antza, Christina, Katsiki, Niki, Zacharis, Evangelos, Attilakos, Achilleas, Sfikas, George, Anagnostis, Panagiotis, Panagiotakos, Demosthenes B., Liberopoulos, Evangelos N.“…Target achievement as per latest guidelines in treated patients using the LDL-C(M/H) (2.5%) and especially LDL-C(Lp(a)corM/H) methods (10.7%) were significantly different than LDL-C(F) (2.9%; P < 0.001). …”
Publicado 2020
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277694por McGenity, Terry J., Gessesse, Amare, Hallsworth, John E., Garcia Cela, Esther, Verheecke‐Vaessen, Carol, Wang, Fengping, Chavarría, Max, Haggblom, Max M., Molin, Søren, Danchin, Antoine, Smid, Eddy J., Lood, Cédric, Cockell, Charles S., Whitby, Corinne, Liu, Shuang‐Jiang, Keller, Nancy P., Stein, Lisa Y., Bordenstein, Seth R., Lal, Rup, Nunes, Olga C., Gram, Lone, Singh, Brajesh K., Webster, Nicole S., Morris, Cindy, Sivinski, Sharon, Bindschedler, Saskia, Junier, Pilar, Antunes, André, Baxter, Bonnie K., Scavone, Paola, Timmis, Kenneth“…Children are also fascinated by the unknown, so, paradoxically, the invisibility of microbes makes them especially fascinating objects for visualization and exploration. …”
Publicado 2020
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277695por Zhang, Ting, Wang, Huien, Wang, Xinling, Yang, Yue, Zhang, Yingkui, Tang, Zengjun, Wang, Li“…CONCLUSIONS: The adolescent pregnancy was related to adverse perinatal (fetal and neonatal) outcomes, such as preterm delivery, stillbirth and neonatal death, especially in younger adolescent pregnancies.…”
Publicado 2020
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277696“…We will also need to support the caregivers who have been on the front line and who will emerge tested from this pandemic: depending on the sustainability of the action capacities of our healthcare system to return to its nominal state and also perhaps, so that it can face consequences resulting from other crises, especially social ones.…”
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277697por Fernando-Macías, Ester, Fernández-García, Maria Teresa, García-Pérez, Eva, Porrero Guerrero, Belén, López-Arévalo, Camilo, Rodríguez-Uría, Raquel, Sanz-Navarro, Sandra, Vázquez-Villa, José Fernando, Muñíz-Salgueiro, María Carmen, Suárez-Fernández, Laura, Galván, José A., Barneo-Caragol, Clara, García-Ocaña, Marcos, de los Toyos, Juan R., Barneo-Serra, Luis“…This emphasizes the importance of the tumor stroma, and especially the CAFs, in the development of cancer.…”
Publicado 2020
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277698“…In both the IBC and non-IBC cases, the proportion of visceral metastases increased in the TNBC subtype, especially brain metastasis (IBC 26.4%, non-IBC 21.2%), which had the largest increase. …”
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277699“…BACKGROUND: Tomato gray leaf spot is a worldwide disease, especially in warm and humid areas. The continuous expansion of greenhouse tomato cultivation area and the frequent introduction of foreign varieties in recent years have increased the severity of the epidemic hazards of this disease in some tomato planting bases annually. …”
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277700por Guo, Xin, Lv, Xiaohui, Ru, Yi, Zhou, Fuxing, Wang, Ning, Xi, Hongqing, Zhang, Kecheng, Li, Jiyang, Chang, Rongyan, Xie, Tianyu, Wang, Xinxin, Li, Baohai, Chen, Yong, Yang, Yanling, Chen, Lubin, Chen, Lin“…Moreover, lncRNA-GC1 exhibited a higher AUC compared with those of CEA, CA72-4, and CA19-9 for early detection of GC with sufficient specificity and sensitivity, especially for patients with GC with negative standard biomarkers. …”
Publicado 2020
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