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  1. 278261
    “…BACKGROUND: In contrast to the large and increasing number of patients with stroke, clinical rehabilitation resources cannot meet their rehabilitation needs. Especially for those discharged, ways to carry out effective rehabilitation training without the supervision of physicians and receive guidance from physicians remain urgent problems to be solved in clinical rehabilitation and have become a research hot spot at home and abroad. …”
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    Clinical Study of a Wearable Remote Rehabilitation Training System for Patients With Stroke: Randomized Controlled Pilot Trial
  2. 278262
    “…CONCLUSION: Our results suggest that the health (and behavior) of primary school-aged children is possibly impacted by the COVID-19 pandemic, with adverse consequences differing by gender and very likely by the pre-pandemic family situation. Especially in girls having a mother with depression or anxiety symptoms, the adverse consequences of the pandemic on mental health seem to be aggregated. …”
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    Trajectories of child mental health, physical activity and screen-time during the COVID-19 pandemic considering different family situations: results from a longitudinal birth cohort
  3. 278263
    por Kassebaum, Nicholas, Kyu, Hmwe Hmwe, Zoeckler, Leo, Olsen, Helen Elizabeth, Thomas, Katie, Pinho, Christine, Bhutta, Zulfiqar A., Dandona, Lalit, Ferrari, Alize, Ghiwot, Tsegaye Tewelde, Hay, Simon I., Kinfu, Yohannes, Liang, Xiaofeng, Lopez, Alan, Malta, Deborah Carvalho, Mokdad, Ali H., Naghavi, Mohsen, Patton, George C., Salomon, Joshua, Sartorius, Benn, Topor-Madry, Roman, Vollset, Stein Emil, Werdecker, Andrea, Whiteford, Harvey A., Abate, Kalkidan Hasen, Abbas, Kaja, Damtew, Solomon Abrha, Ahmed, Muktar Beshir, Akseer, Nadia, Al-Raddadi, Rajaa, Alemayohu, Mulubirhan Assefa, Altirkawi, Khalid, Abajobir, Amanuel Alemu, Amare, Azmeraw T., Antonio, Carl A. T., Arnlov, Johan, Artaman, Al, Asayesh, Hamid, Avokpaho, Euripide Frinel G. Arthur, Awasthi, Ashish, Ayala Quintanilla, Beatriz Paulina, Bacha, Umar, Betsu, Balem Demtsu, Barac, Aleksandra, Bärnighausen, Till Winfried, Baye, Estifanos, Bedi, Neeraj, Bensenor, Isabela M., Berhane, Adugnaw, Bernabe, Eduardo, Bernal, Oscar Alberto, Beyene, Addisu Shunu, Biadgilign, Sibhatu, Bikbov, Boris, Boyce, Cheryl Anne, Brazinova, Alexandra, Hailu, Gessessew Bugssa, Carter, Austin, Castañeda-Orjuela, Carlos A., Catalá-López, Ferrán, Charlson, Fiona J., Chitheer, Abdulaal A., Choi, Jee-Young Jasmine, Ciobanu, Liliana G., Crump, John, Dandona, Rakhi, Dellavalle, Robert P., Deribew, Amare, deVeber, Gabrielle, Dicker, Daniel, Ding, Eric L., Dubey, Manisha, Endries, Amanuel Yesuf, Erskine, Holly E., Faraon, Emerito Jose Aquino, Faro, Andre, Farzadfar, Farshad, Fernandes, Joao C., Fijabi, Daniel Obadare, Fitzmaurice, Christina, Fleming, Thomas D., Flor, Luisa Sorio, Foreman, Kyle J., Franklin, Richard C., Fraser, Maya S., Frostad, Joseph J., Fullman, Nancy, Gebregergs, Gebremedhin Berhe, Gebru, Alemseged Aregay, Geleijnse, Johanna M., Gibney, Katherine B., Gidey Yihdego, Mahari, Ginawi, Ibrahim Abdelmageem Mohamed, Gishu, Melkamu Dedefo, Gizachew, Tessema Assefa, Glaser, Elizabeth, Gold, Audra L., Goldberg, Ellen, Gona, Philimon, Goto, Atsushi, Gugnani, Harish Chander, Jiang, Guohong, Gupta, Rajeev, Tesfay, Fisaha Haile, Hankey, Graeme J., Havmoeller, Rasmus, Hijar, Martha, Horino, Masako, Hosgood, H. Dean, Hu, Guoqing, Jacobsen, Kathryn H., Jakovljevic, Mihajlo B., Jayaraman, Sudha P., Jha, Vivekanand, Jibat, Tariku, Johnson, Catherine O., Jonas, Jost, Kasaeian, Amir, Kawakami, Norito, Keiyoro, Peter N., Khalil, Ibrahim, Khang, Young-Ho, Khubchandani, Jagdish, Ahmad Kiadaliri, Aliasghar A., Kieling, Christian, Kim, Daniel, Kissoon, Niranjan, Knibbs, Luke D., Koyanagi, Ai, Krohn, Kristopher J., Kuate Defo, Barthelemy, Kucuk Bicer, Burcu, Kulikoff, Rachel, Kumar, G. Anil, Lal, Dharmesh Kumar, Lam, Hilton Y., Larson, Heidi J., Larsson, Anders, Laryea, Dennis Odai, Leung, Janni, Lim, Stephen S., Lo, Loon-Tzian, Lo, Warren D., Looker, Katharine J., Lotufo, Paulo A., Magdy Abd El Razek, Hassan, Malekzadeh, Reza, Markos Shifti, Desalegn, Mazidi, Mohsen, Meaney, Peter A., Meles, Kidanu Gebremariam, Memiah, Peter, Mendoza, Walter, Abera Mengistie, Mubarek, Mengistu, Gebremichael Welday, Mensah, George A., Miller, Ted R., Mock, Charles, Mohammadi, Alireza, Mohammed, Shafiu, Monasta, Lorenzo, Mueller, Ulrich, Nagata, Chie, Naheed, Aliya, Nguyen, Grant, Nguyen, Quyen Le, Nsoesie, Elaine, Oh, In-Hwan, Okoro, Anselm, Olusanya, Jacob Olusegun, Olusanya, Bolajoko O., Ortiz, Alberto, Paudel, Deepak, Pereira, David M., Perico, Norberto, Petzold, Max, Phillips, Michael Robert, Polanczyk, Guilherme V., Pourmalek, Farshad, Qorbani, Mostafa, Rafay, Anwar, Rahimi-Movaghar, Vafa, Rahman, Mahfuzar, Rai, Rajesh Kumar, Ram, Usha, Rankin, Zane, Remuzzi, Giuseppe, Renzaho, Andre M. N., Roba, Hirbo Shore, Rojas-Rueda, David, Ronfani, Luca, Sagar, Rajesh, Sanabria, Juan Ramon, Kedir Mohammed, Muktar Sano, Santos, Itamar S., Satpathy, Maheswar, Sawhney, Monika, Schöttker, Ben, Schwebel, David C., Scott, James G., Sepanlou, Sadaf G., Shaheen, Amira, Shaikh, Masood Ali, She, June, Shiri, Rahman, Shiue, Ivy, Sigfusdottir, Inga Dora, Singh, Jasvinder, Silpakit, Naris, Smith, Alison, Sreeramareddy, Chandrashekhar, Stanaway, Jeffrey D., Stein, Dan J., Steiner, Caitlyn, Sufiyan, Muawiyyah Babale, Swaminathan, Soumya, Tabarés-Seisdedos, Rafael, Tabb, Karen M., Tadese, Fentaw, Tavakkoli, Mohammad, Taye, Bineyam, Teeple, Stephanie, Tegegne, Teketo Kassaw, Temam Shifa, Girma, Terkawi, Abdullah Sulieman, Thomas, Bernadette, Thomson, Alan J., Tobe-Gai, Ruoyan, Tonelli, Marcello, Tran, Bach Xuan, Troeger, Christopher, Ukwaja, Kingsley N., Uthman, Olalekan, Vasankari, Tommi, Venketasubramanian, Narayanaswamy, Vlassov, Vasiliy Victorovich, Weiderpass, Elisabete, Weintraub, Robert, Gebrehiwot, Solomon Weldemariam, Westerman, Ronny, Williams, Hywel C., Wolfe, Charles D. A., Woodbrook, Rachel, Yano, Yuichiro, Yonemoto, Naohiro, Yoon, Seok-Jun, Younis, Mustafa Z., Yu, Chuanhua, Zaki, Maysaa El Sayed, Zegeye, Elias Asfaw, Zuhlke, Liesl Joanna, Murray, Christopher J. L., Vos, Theo
    Publicado 2017
    “…Maternal and reproductive health remains a key cause of disease burden in adolescent females, especially in lower-SDI countries. In low-SDI countries, mortality is the primary driver of health loss for children and adolescents, whereas disability predominates in higher-SDI locations; the specific pattern of epidemiological transition varies across diseases and injuries. …”
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    Child and Adolescent Health From 1990 to 2015: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study
  4. 278264
    “…CONCLUSIONS: This study highlights 1) a high prevalence of HPV infection among females with a decreasing tendency towards 2012–2018, especially for young women under the age of 21 prior to mass HPV vaccination; 2) HPV52, − 16 and − 58 were the predominant HPV genotypes, suggesting potential use of HPV vaccine covering these HPV genotypes in Southern China.…”
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    Prevalence and genotype distribution of HPV infection among 214,715 women from Southern China, 2012–2018: baseline measures prior to mass HPV vaccination
  5. 278265
    “…BACKGROUND: Self testing for HIV is a targeted intervention with the potential to increase the access, uptake and frequency of HIV testing and more effectively reach the undiagnosed, especially in priority populations. The objectives of this study were to (1) evaluate the INSTI HIV self-test performance compared with laboratory reference testing, (2) document if intended users can perform the steps to use the HIV self-test device, and (3) document if intended users can successfully interpret contrived positive, negative, and invalid results. …”
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    An observed, prospective field study to evaluate the performance and acceptance of a blood-based HIV self-test in Canada
  6. 278266
    “…CONCLUSIONS/INTERPRETATION: Clusters based on C-peptide instead of HOMA2 measures resemble those based on HOMA2 measures, especially for SIDD, SIRD and MOD. By adding HDL-cholesterol, the MARD cluster based upon HOMA2 measures resulted in the current clustering into two clusters, with one cluster having high HDL levels. …”
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    Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study
  7. 278267
    “…The reported incidence of natural focal diseases, especially malaria and dengue, decreased during the outbreak of COVID-19 in 2020. …”
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    Impact of interventions on the incidence of natural focal diseases during the outbreak of COVID-19 in Jiangsu Province, China
  8. 278268
    “…BACKGROUND: Traumatic brain injury (TBI) and severe blood loss resulting in hemorrhagic shock (HS) represent leading causes of trauma-induced mortality, especially when co-occurring in pre-hospital settings where standard therapies are not readily available. …”
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    17α-Ethinyl estradiol-3-sulfate increases survival and hemodynamic functioning in a large animal model of combined traumatic brain injury and hemorrhagic shock: a randomized control trial
  9. 278269
    “…Furthermore, the delivery of miR-6766-3p into activated-LX2 cells decreased cell proliferation, chemotaxis and profibrotic effects, and further investigation demonstrated that the expression of target gene TGFβRII and its downstream SMADs proteins, especially phosphorylated protein p-SMAD2/3 was also notably down-regulated by miR-6766-3p. …”
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    3D hESC exosomes enriched with miR-6766-3p ameliorates liver fibrosis by attenuating activated stellate cells through targeting the TGFβRII-SMADS pathway
  10. 278270
    “…BACKGROUND: Safety after the second dose of the SARS-CoV-2 vaccine remains to be elucidated, especially among individuals reporting adverse events after their first dose. …”
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    Impact of a delayed second dose of mRNA vaccine (BNT162b2) and inactivated SARS-CoV-2 vaccine (CoronaVac) on risks of all-cause mortality, emergency department visit, and unscheduled hospitalization
  11. 278271
    “…BACKGROUND: Chronic pain affects approximately 30% of the general population, severely degrades quality of life (especially in older adults) and professional life (inability or reduction in the ability to work and loss of employment), and leads to billions in additional health care costs. …”
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    eDOL mHealth App and Web Platform for Self-monitoring and Medical Follow-up of Patients With Chronic Pain: Observational Feasibility Study
  12. 278272
    “…BACKGROUND: Use of kinase inhibitors such as dasatinib and imatinib might increase the risk of opportunistic infections, especially Epstein-Barr virus (EBV) and cytomegalovirus (CMV) infections. …”
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    Effect of sorafenib maintenance on Epstein-Barr virus and cytomegalovirus infections in patients with FLT3-ITD AML undergoing allogeneic hematopoietic stem cell transplantation: a secondary analysis of a randomized clinical trial
  13. 278273
    “…However, the ECG is not a sensitive method of detecting left ventricular hypertrophy (LVH), and as far as we know, it cannot detect changes in left ventricular geometry (LVG) at early stages, especially before LVH is present. Its sensitivity is particularly low for obese patients. …”
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    Detection of left ventricular hypertrophy on the ECG through machine learning with a focus on obesity
  14. 278274
    “…Unexpectedly, flow cytometry showed that NEO-201 also binds to circulating regulatory T cells and reduction of the quantities of these cells was observed especially in patients with SD. CONCLUSIONS: NEO-201 was safe and well tolerated at the MTD of 1.5 mg/kg, with neutropenia being the most common adverse event. …”
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    First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors
  15. 278275
    “…Almost age groups have shown good knowledge of diabetes, especially participants aged above 55 (93.8%). However, most individuals have examined blood pressure (82.3%), whereas fewer than half had screened for blood sugar (64.4%). …”
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    Assessment the awareness toward hypertension and diabetes mellitus: Syrian cross sectional study
  16. 278276
    “…Previous studies have shown that the cell cycle regulation plays an important role in HIV-1 infection, especially at the G2/M checkpoint. ATR, Chk1, Cdc25C and CDK1 are key genes of G2/M checkpoint. …”
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    Biomedical association analysis between G2/M checkpoint genes and susceptibility to HIV-1 infection and AIDS progression from a northern chinese MSM population
  17. 278277
    “…CONCLUSIONS: In patients with symptomatic COPD receiving high-dose ICS/LABA, adding a long-acting muscarinic antagonist while decreasing the ICS dose by switching to medium-dose extrafine BDP/FF/G was associated with improved airway indices, especially in the distal airways, together with improvements in respiratory health status. …”
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    The effect of inhaled extrafine beclometasone dipropionate/formoterol fumarate/glycopyrronium bromide on distal and central airway indices, assessed using Functional Respiratory Imaging in COPD (DARWiIN)
  18. 278278
    “…However, little is known about the prevalence and patterns of long-term medical conditions in HCWs, especially those from ethnic minorities. This study evaluated the burden of multiple long-term conditions (MLTCs), i.e. the presence of two or more single long-term conditions (LTCs), among HCWs in the United Kingdom (UK) and variation by ethnicity and migration status. …”
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    Association between ethnicity and migration status with the prevalence of single and multiple long-term conditions in UK healthcare workers
  19. 278279
    “…Further, random controlled trial especially effectiveness of nutritional education interventions trial is important. …”
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    Prevalence of anemia and its associated factors among children aged 6–23 months, in Ethiopia: a systematic review and meta analysis
  20. 278280
    por Agua-Agum, Junerlyn, Ariyarajah, Archchun, Aylward, Bruce, Bawo, Luke, Bilivogui, Pepe, Blake, Isobel M., Brennan, Richard J., Cawthorne, Amy, Cleary, Eilish, Clement, Peter, Conteh, Roland, Cori, Anne, Dafae, Foday, Dahl, Benjamin, Dangou, Jean-Marie, Diallo, Boubacar, Donnelly, Christl A., Dorigatti, Ilaria, Dye, Christopher, Eckmanns, Tim, Fallah, Mosoka, Ferguson, Neil M., Fiebig, Lena, Fraser, Christophe, Garske, Tini, Gonzalez, Lice, Hamblion, Esther, Hamid, Nuha, Hersey, Sara, Hinsley, Wes, Jambei, Amara, Jombart, Thibaut, Kargbo, David, Keita, Sakoba, Kinzer, Michael, George, Fred Kuti, Godefroy, Beatrice, Gutierrez, Giovanna, Kannangarage, Niluka, Mills, Harriet L., Moller, Thomas, Meijers, Sascha, Mohamed, Yasmine, Morgan, Oliver, Nedjati-Gilani, Gemma, Newton, Emily, Nouvellet, Pierre, Nyenswah, Tolbert, Perea, William, Perkins, Devin, Riley, Steven, Rodier, Guenael, Rondy, Marc, Sagrado, Maria, Savulescu, Camelia, Schafer, Ilana J., Schumacher, Dirk, Seyler, Thomas, Shah, Anita, Van Kerkhove, Maria D., Wesseh, C. Samford, Yoti, Zabulon
    Publicado 2016
    “…The principal limitation of our analysis is limited data quality, with cases not being entered into the database, cases not reporting exposures, or data being entered incorrectly (especially dates, and possible misclassifications). …”
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    Exposure Patterns Driving Ebola Transmission in West Africa: A Retrospective Observational Study
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