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  1. 278781
    “…A patient centred treatment approach is especially crucial when undertaking riskier treatment strategies, with all treatment consultations requiring a careful discussion of the risks and benefits. …”
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    OA20 Combining B cell depletion and JAKi for difficult-to-treat rheumatoid arthritis
  2. 278782
    “…Screening for syphilis prior to immunosuppression may be necessary for high-risk patients, especially with the rising use of biologic therapies. …”
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    P30 An unusual infective cause of inflammatory arthritis
  3. 278783
    “…CONCLUSION: Multi-MDRO carriage is common among NH residents with MDROs harbored at multiple body sites. Co-carriage was especially high among those harboring a carbapenem-resistant organism, likely reflecting accrued MDROs from extensive and repeated antibiotic exposure. …”
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    2075. Multidrug-Resistant Organism (MDRO) Co-Carriage Patterns in Nursing Homes (NHs): Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant Enterococci (VRE), Extended Spectrum beta-lactamase (ESBL) producers, Carbapenem-resistant Enterobacterales (CRE), Carbapenem-resistant Acinetobacter baumannii (CRAB), and Candida auris
  4. 278784
    por Tetlow, Lynne C, Woolley, David E
    Publicado 1999
    “…These opposite effects may be relevant to the processes of joint destruction, especially cartilage loss, as the ability of 1α,25(OH)(2)D(3) to potentiate MMP-1 and MMP-3 expression by 'activated' chondrocytes might facilitate intrinsic cartilage chondrolysis in vivo. …”
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    The effects of 1α,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion
  5. 278785
    por Elsberg, Charles A.
    Publicado 1899
    “…In the last few decades, the advances made in all the branches of medicine—especially in pathology, bacteriology and surgery—have been due to a great extent to the generalization of the results of animal experimentation. …”
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    AN EXPERIMENTAL INVESTIGATION OF THE TREATMENT OF WOUNDS OF THE HEART BY MEANS OF SUTURE OF THE HEART MUSCLE
  6. 278786
    “…The first addressed ethical aspects regarding the principles of beneficence, autonomy and justice, and the second addressed those regarding radiation exposition, especially when used within studies. DISCUSSION: The discriminatory power of CT coronary angiography to identify patients with obstructive (above 50 %) coronary stenoses should be regarded as “high diagnostic evidence”, to identify patients without coronary stenoses as “persuasive diagnostic evidence”. …”
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    CT coronary angiography vs. invasive coronary angiography in CHD
  7. 278787
    por Teodoreanu, R, Popescu, SA, Lascar, I
    Publicado 2014
    “…Another risk is that of infection with Clostridium difficile following the prolonged utilization of broad-spectrum antibiotics, especially in patients with associated diseases and reduced immunity per primam. …”
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    Electrical injuries. Biological values measurements as a prediction factor of local evolution in electrocutions lesions
  8. 278788
    “…To assess whether there is an impact of MDA on malaria transmission in the longer term requires more quasi experimental studies with the intention of elimination, especially in low‐ and moderate‐transmission settings. …”
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    Mass drug administration for malaria
  9. 278789
    “…Supplementation probably does increase blood concentrations of vitamin D and zinc (data not pooled, vitamin D: 4 trials, 299 participants, zinc: 4 trials, 484 participants, moderate certainty evidence) and may also increase blood concentrations of vitamin A (data not pooled, 3 trials, 495 participants, low certainty evidence), especially in those who are deficient. AUTHORS' CONCLUSIONS: The analyses of the available trials have not revealed consistent clinically important benefits with routine multiple micronutrient supplementation in people living with HIV. …”
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    Micronutrient supplementation in adults with HIV infection
  10. 278790
    “…INDIVIDUALIZING CARE IN PATIENTS WITH ASSOCIATED CONDITIONS AND COMORBIDITIES: Managing patients with multiple conditions can be complex, especially when recommendations applicable to coexisting illnesses are discordant or interacting.(8) The guidelines are intended to define practices meeting the needs of patients in most, but not all, circumstances. …”
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    2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
  11. 278791
    Publicado 2017
    “…Comparisons of observed levels of YLLs by countries, relative to the level of YLLs expected on the basis of SDI alone, highlighted distinct regional patterns including the greater than expected level of YLLs from malaria and from HIV/AIDS across sub-Saharan Africa; diabetes mellitus, especially in Oceania; interpersonal violence, notably within Latin America and the Caribbean; and cardiomyopathy and myocarditis, particularly in eastern and central Europe. …”
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    Global, regional, and national age-sex specific mortality for 264 causes of death, 1980–2016: a systematic analysis for the Global Burden of Disease Study 2016
  12. 278792
    “…Thus, the significantly reduced abundance of MSY2 protein, especially at the SCRD and the spindle may disturb the spatial control and timely recruitment, deadenylation and degradation of developmentally important RNAs. …”
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    Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes
  13. 278793
    “…CONCLUSION: Different pathological types of nephritis presented different expression patterns of immunoglobulin and complement, especially IgA and IgG, which suggested different pathogenesis involved in the development of IgAN and MN. …”
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    A pilot and comparative study between pathological and serological levels of immunoglobulin and complement among three kinds of primary glomerulonephritis
  14. 278794
    “…This treatment schedule should be discussed and recommended, especially for women with stage III or serous cancers, or both, as part of shared decision making between doctors and patients. …”
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    Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial
  15. 278795
    “…Evidence for treatment of inflammatory arthritis in the context of CF is poor and concerns include risks associated with immunosuppression (especially in cases with severe bronchiectasis), polypharmacy, comorbid diabetes and liver disease. …”
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    24. Chronic inflammatory arthritis in the context of cystic fibrosis
  16. 278796
    por Ghuman, Hira, Samaranayaka, Muditha
    Publicado 2019
    “…It will also highlight the disease burden of vasculitis especially due to the rare adverse effects this patient suffered due medication. …”
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    49. Giant cell arteritis and Takayasu arteritis: two sides of the same coin in an elderly female?
  17. 278797
    por Chakravorty, Mithun, Mathew, Rengi
    Publicado 2019
    “…Extensive investigations are needed to exclude mimics such as infection, malignancy (especially haematological) and autoimmune conditions. …”
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    8. An autoinflammatory syndrome resembling Castleman’s disease with excellent response to IL-6 blockade
  18. 278798
    por Bracha, H. Stefan
    Publicado 2006
    “…Neuroevolutionary insights relevant to fear circuitry symptoms that primarily emerge overconsolidationally (especially Combat related Posttraumatic Stress Disorder) are presented. …”
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    Human brain evolution and the “Neuroevolutionary Time-depth Principle:” Implications for the Reclassification of fear-circuitry-related traits in DSM-V and for studying resilience to warzone-related posttraumatic stress disorder
  19. 278799
    “…CONCLUSIONS: In these extraordinary circumstances, our reality was among the most affected and was able to hold the impact thanks to the immediate great response set in place by the operators, although it costed us an effort especially the one to try to guarantee a high quality level of assistance and care compared to the huge wave of patients in seriously bad conditions. …”
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    Intensive care for seriously ill patients affected by novel coronavirus sars - CoV – 2: Experience of the Crema Hospital, Italy
  20. 278800
    “…The conference will help me deepen my understanding of epidemic rheumatology which will be useful for my clinical practice going forward, especially if there is a second wave of the COVID-19 pandemic. …”
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    EP08 A case of granulomatosis with polyangiitis complicated by COVID-19: challenges in diagnosis and management
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