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278861por Chughtai, Talat, Parchani, Ashok, Strandvik, Gustav, Verma, Vishy, Arumugam, Suresh, El-Menyar, Ayman, Rizoli, Sandro, Al-Thani, Hassan“…Similarly, critically injured trauma patients managed in a dedicated trauma intensive care unit (TICU), has been shown to improve outcomes, especially for polytrauma patients with traumatic brain injury (TBI).(3) In fact, the American College of Surgeons (ACS) Committee on Trauma requires verified trauma centers to have a designated ICU, and that a trauma surgeon be its director.(4) Furthermore, studies have shown that for TBI, it is not necessary for this ICU to be a neurocritical care unit, but rather it should be a unit that is dedicated to trauma, that has standardized protocols for TBI management.(5,6) In fact, the outcomes are better in the latter, with lower mortality in multiple-injured patients with TBI, when admitted to a TICU (versus a medical-surgical ICU or neurocritical care unit).(3) These benefits were shown to increase, with increased injury severity. …”
Publicado 2020
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278862por Chawla, Rajesh, Dixit, Subhal B, Zirpe, Kapil Gangadhar, Chaudhry, Dhruva, Khilnani, G C, Mehta, Yatin, Khatib, Khalid Ismail, Jagiasi, Bharat G, Chanchalani, Gunjan, Mishra, Rajesh C, Samavedam, Srinivas, Govil, Deepak, Gupta, Sachin, Prayag, Shirish, Ramasubban, Suresh, Dobariya, Jayesh, Marwah, Vikas, Sehgal, Inder, Jog, Sameer Arvind, Kulkarni, Atul Prabhakar“…(UPP) We suggest using flow trigger over pressure triggering in assisted modes, as it provides better patient ventilator synchrony. Especially in COPD patients, flow triggering has been found to benefit auto PEEP. (3B) D. …”
Publicado 2020
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278863por Almaghraby, Abdullah, Jaju, Alok, Ryan, Maura E, Rychlik, Karen, Habiby, Reema L, Brickman, Wendy“…The clinical significance of this deposition is unclear at this time but warrants caution especially in pediatric population who have a longer expected lifespan to manifest any delayed effects. …”
Publicado 2020
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278864por Flower, Luke, Gale, Aislinn, Elfar, Eman, Manson, Jessica, Tattersal, Rachel, Quick, Vanessa“…Adult clinicians should be aware of PIMS-TS which may rarely occur in young adults, especially those of African descent. The CDC definition extends to those aged up to 21. …”
Publicado 2020
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278865por Stegeman, Inge, Ochodo, Eleanor A, Guleid, Fatuma, Holtman, Gea A., Yang, Bada, Davenport, Clare, Deeks, Jonathan J, Dinnes, Jacqueline, Dittrich, Sabine, Emperador, Devy, Hooft, Lotty, Spijker, René, Takwoingi, Yemisi, Van den Bruel, Ann, Wang, Junfeng, Langendam, Miranda, Verbakel, Jan Y, Leeflang, Mariska MG“…These laboratory tests may be useful for the triage of people with potential COVID‐19 to prioritize them for different levels of treatment, especially in situations where time and resources are limited. …”
Publicado 2020
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278866por Wood, William A., Neuberg, Donna S., Thompson, John Colton, Tallman, Martin S., Sekeres, Mikkael A., Sehn, Laurie H., Anderson, Kenneth, Goldberg, Aaron D, Pennell, Nathan A, Niemeyer, Charlotte M., Tucker, Emily, Hewitt, Kathleen, Plovnick, Robert M, Hicks, Lisa K.“…Additionally, patients with blood cancer are often older, may have comorbid illness including hypertension and diabetes, and may be especially susceptible to complications of COVID-19 include hypercoagulability and thrombosis. …”
Publicado 2020
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278867por Melbye, Silje Marie, Haug, Sofie Cecilia Dietrich, Fenstad, Anne Marie, Furnes, Ove, Gjertsen, Jan-Erik, Hallan, Geir“…Due to an increased risk of periprosthetic fracture, caution with the use of the uncemented Corail stem in patients older than 70 years, especially in women, is warranted. Poorer stem survival should also be expected with the use of small stem sizes. …”
Publicado 2021
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278868por Molica, Stefano, Laurenti, Luca, Ghia, Paolo, Coscia, Marta, Cuneo, Antonio, Gaidano, Gianluca, Mauro, Francesca, Frustaci, Anna Maria, Vallisa, Daniele, Pane, Fabrizio, Gualberti, Giuliana, Iannella, Emilia, Finsinger, Paola, Caira, Morena, Sportoletti, Paolo“…In contrast to previously published DCEs (1-2), where PFS was the most important attribute, in the CHOICE study pts put much more emphasis on their concerns about possible infections: this could be due to the influence of the 1 (st) Covid-19 pandemic wave, with the relevant feeling of uncertainty, also due to the great attention that media has dedicated to the issue of infection in general, especially for vulnerable individuals such as CLL pts. …”
Publicado 2021
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278869por Gavriatopoulou, Maria, Terpos, Evangelos, Malandrakis, Panagiotis, Ntanasis-Stathopoulos, Ioannis, Briasoulis, Alexandros, Gumeni, Sentiljana, Fotiou, Despina, Papanagnou, Eleni-Dimitra, Migkou, Magdalini, Theodorakakou, Foteini, Eleutherakis-Papaiakovou, Evangelos, Kanellias, Nikolaos, Trougakos, Ioannis P., Kastritis, Efstathios, Dimopoulos, Meletios-Athanasios“…Introduction: Recent data suggest a suboptimal antibody response to COVID-19 vaccination in patients with multiple myeloma (MM), especially under treatment. Herein, we evaluated the development of neutralizing antibodies (NAbs) against SARS-CoV-2 in non-vaccinated MM patients who were diagnosed with COVID-19 compared to MM patients after full vaccination with the mRNA BNT162b2 vaccine. …”
Publicado 2021
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278870por Leiva, Orly, Campia, Umberto, Snyder, Julia, Barns, Briana, Rizzo, Samantha, Khairani, Candrika, Al-Samkari, Hanny, Karp Leaf, Rebecca, Rosovsky, Rachel P., Goodarzi, Katayoon, Fathi, Amir T., Goldhaber, Samuel Z., Piazza, Gregory, Hobbs, Gabriela“…Patients with MPNs, especially PH-negative, have increased risk of thrombotic complications. …”
Publicado 2021
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278871por Shapiro, Lauren C, Gali, Radhika, Thakkar, Astha, Gonzalez-Lugo, Jesus D, Bazarbachi, Abdul Hamid, Rahman, Shafia, Pradhan, Kith, Fehn, Karen, Abreu, Michelly, Kornblum, Noah, Gritsman, Kira, Goldfinger, Mendel, Shastri, Aditi, Mantzaris, Ioannis, Braunschweig, Ira, Halmos, Balazs, Verma, Amit, McCort, Margaret, Bachier-Rodriguez, Lizamarie, Sica, R. Alejandro“…We observed significantly lower seroconversion rates in pts with Non-Hodgkin lymphoma (p=0.005) and pts who received: cytotoxic chemotherapy (p=0.002), IVIG (p=0.01), CAR-T cell therapy (p=0.00002), and CD20 monoclonal antibodies (Ab) (p=0.0000008) especially within 6 mo of Spike Ab evaluation (p=0.01). …”
Publicado 2021
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278872por Kusch, Michael, Labouvie, Hildegard, Schiewer, Vera, Talalaev, Natalie, Cwik, Jan C., Bussmann, Sonja, Vaganian, Lusine, Gerlach, Alexander L., Dresen, Antje, Cecon, Natalia, Salm, Sandra, Krieger, Theresia, Pfaff, Holger, Lemmen, Clarissa, Derendorf, Lisa, Stock, Stephanie, Samel, Christina, Hagemeier, Anna, Hellmich, Martin, Leicher, Bernd, Hültenschmidt, Gregor, Swoboda, Jessica, Haas, Peter, Arning, Anna, Göttel, Andrea, Schwickerath, Kathrin, Graeven, Ullrich, Houwaart, Stefanie, Kerek-Bodden, Hedy, Krebs, Steffen, Muth, Christiana, Hecker, Christina, Reiser, Marcel, Mauch, Cornelia, Benner, Jennifer, Schmidt, Gerdamarie, Karlowsky, Christiane, Vimalanandan, Gisela, Matyschik, Lukas, Galonska, Lars, Francke, Annette, Osborne, Karin, Nestle, Ursula, Bäumer, Markus, Schmitz, Kordula, Wolf, Jürgen, Hallek, Michael“…DISCUSSION: Demands on quality, effectiveness and cost-effectiveness of in the German health care system are increasing, whereas financial resources are declining, especially for psychosocial services. At the same time, knowledge about evidence-based screening, assessment and intervention in cancer patients and about the provision of psychosocial oncological services is growing continuously. …”
Publicado 2022
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278873por Sharma, Meenakshi“…The detectors of ALICE at the LHC, are especially designed to study the physics of the QGP produced in heavy-ion collisions. …”
Publicado 2023
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278874por Köstner, S“…Before the detectors are placed into the final experiment they have to be tested carefully. Especially for long modules where silicon microstrip sensors are wire bonded together, short circuits and missing wire bonds are to be expected. …”
Publicado 2005
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278875“…The localization of lesions after injection of virus into the muscles of one leg indicated that in the young the invasion occurred along the local peripheral nerves, especially the motor fibers (neurons destroyed in the lumbar cord with those in the spinal ganglia intact), after a primary attack on the muscle itself. …”
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278876por Cuadrado-Lavín, Antonio, Olmos, José Manuel, Cifrian, José Manuel, Gimenez, Teresa, Gandarillas, Marco Antonio, García-Saiz, Mar, Rebollo, Maria Henar, Martínez-Taboada, Victor, López-Hoyos, Marcos, Fariñas, María Carmen, Crespo, Javier“…Exclusion criteria: 1) Previous infection with SARS CoV2 (positive coronavirus PCR or positive serology with SARS Cov2 negative PCR and absence of symptoms); 2) Current treatment with hydroxychloroquine or chloroquine; 3) Hypersensitivity, allergy or any contraindication for taking hydroxychloroquine, in the technical sheet; 4) Previous or current treatment with tamoxifen or raloxifene; 5) Previous eye disease, especially maculopathy; 6) Known heart failure (Grade III to IV of the New York Heart Association classification) or prolonged QTc; 7) Any type of cancer (except basal cell) in the last 5 years; 6) Refusal to give informed consent; 8) Evidence of any other unstable or clinically significant untreated immune, endocrine, hematological, gastrointestinal, neurological, neoplastic or psychiatric illness; 9) Antibodies positive for the human immunodeficiency virus; 10) Significant kidney or liver disease; 11) Pregnancy or lactation. …”
Publicado 2020
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278877por Seidel, Danila, Cornely, Oliver, Zarrouk, Marouan, Koehler, Philipp, Meis, Jacques F, Salmanton-García, Jon, Vehreschild, Jörg Janne, Christner, Martin, Gräfe, Stefanie K, Falces-Romero, Iker, Lagrou, Katrien, Maertens, Johan, Reséndiz- Sharpe, Agustín, Racil, Zdenek, Weinbergerová, Barbora, Valerio, Maricela, Muñoz, Patricia, Blennow, Ola, Rammaert, Blandine, Ostojic, Alen, Govic, Yohann Le, Lass-Flörl, Cornelia, Rössler, Susann, van Dijk, Karin, de Jong, Nick, Steinmann, Jörg, Desoubeaux, Guillaume, Alakel, Nael, Klimko, Nikolay, Schalk, Enrico, Brenier-Pinchart, Marie-Pierre, Garcia-Vidal, Carolina, Bergeron, Anne, Cho, Sung-Yeon, Melchers, Willem J G, Vehreschild, Maria J G T, Verweij, Paul E“…Intensive care unit 1-year survival probability for patients with azole-resistant and azole-susceptible invasive aspergillosis [Image: see text] CONCLUSION: Azole-resistance in IA is associated with worse outcome, especially in critically ill patients. Susceptibility testing should be considered in patients with a suspected azole-resistant IA to support treatment decisions. …”
Publicado 2020
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278878por Wang, Emily, Kuhn, Theresa, Lahiri, Cecile, Nguyen, Minh, Ofotokun, Ighovwerha, Abraham, Rachael, Easley, Kirk, Mosunjac, Marina, Tadros, Talaat, Finneran, Catherine, Flowers, Lisa“…DISCUSSION/SIGNIFICANCE OF IMPACT: Non-surgical treatments that decrease the morbidity and risk of progression of premalignant HPV-related cervical disease are greatly needed, especially in low-resource settings and among women experiencing barriers to care and/or at high risk for disease progression. …”
Publicado 2020
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278879por CERN. Geneva“…<br> Because of the strong third party presence in the finance industry, such opportunities are few and far between, but they are there, especially as we expand sideways into related verticals such as the smaller hedge funds and energy companies. …”
Publicado 2007
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278880por Meng, Zhaoxia“…However, the challenge at the hadron collider is the background understanding and measurement, which is the first and indispensable work to discover any new particle. Especially for the channel with the τ lepton decaying hadronically, the signal suffer from overwhelming background from QCD multi-jets which has the largest pro- duction cross section in p-p collisions at the LHC. …”
Publicado 2011
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