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  1. 41221
    “…TRIAL REGISTRATION: Tallinn Medical Research Ethical Committee decision #1724, 18.06.2009…”
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    Understanding drug uptake and binding within targeted disease micro-environments in patients: a new tool for translational medicine
  2. 41222
    “…After obtaining institutional ethical approval, patients with different types and stages of cancer from the three major ethnic groups (Malay, Chinese and Indian) were approached. …”
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    A qualitative exploration of Malaysian cancer patients’ perceptions of cancer screening
  3. 41223
    “…In conclusion, the aforementioned promising techniques remain largely experimental and still require extensive research, which should address, among other concerns, ethical and biosafety issues, such as gamete epigenetic status, ploidy, and chromatin integrity.…”
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    Biotechnological approaches to the treatment of aspermatogenic men
  4. 41224
    “…This study aimed to investigate ‘standard’ rehabilitation care in the UK after total hip replacement (THR) as well as determine whether PRT was part of ‘standard’ care. METHODS: After ethical approval, questionnaire item development about rehabilitation practice was guided by a focus group interview (after informed consent) with physiotherapists (n = 4; >5 years post-qualification) who regularly treated THR patients. …”
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    What does standard rehabilitation practice after total hip replacement in the UK entail? results of a mixed methods study
  5. 41225
    “…Objectives: Update on clinical results obtained by the first worldwide facial transplantation teams as well as review of the literature concerning the main surgical, immunological, ethical, and follow-up aspects described on facial transplanted patients. …”
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    Facial transplantation: A concise update
  6. 41226
    por Zetterqvist, Anna V., Mulinari, Shai
    Publicado 2013
    “…European politicians and industry have cited Sweden as an excellent example of self-regulation based on an ethical code. This paper considers antidepressant advertising in Sweden to uncover the strengths and weaknesses of self-regulation. …”
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    Misleading Advertising for Antidepressants in Sweden: A Failure of Pharmaceutical Industry Self-Regulation
  7. 41227
    “…All experiments involving animal subjects were carried out with the approval of animal care and use Ethical Committee of Cukurova University. Experiments were performed on female Albino-Wistar rats (200-260 g; n = 40). …”
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    Dexmedetomidine modifies uterine contractions in pregnancy terms of rats
  8. 41228
    “…Only 56 % of the protocols provided information on publication policy, and 65 % required the involvement of ethic committees. The adherence to current quality recommendations was average, but the compliance of NIS performed by member companies of the Association of Research-Based Pharmaceutical Companies was significantly higher than that of other sponsors. …”
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    A 1-year cross-sectional analysis of non-interventional post-marketing study protocols submitted to the German Federal Institute for Drugs and Medical Devices (BfArM)
  9. 41229
    “…However, when diversity is taken seriously it can open up new perspectives to underpin the ethical framework of EoL care.…”
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    Diversity in Defining End of Life Care: An Obstacle or the Way Forward?
  10. 41230
    “…While LTOCs used control groups, adjusted for multiple covariates, had higher external validity, and favorable ethical, practical and cost considerations, their limitations included potential selection bias due to lack of placebo comparisons and randomization. …”
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    Validity, Significance, Strengths, Limitations, and Evidentiary Value of Real-World Clinical Data for Combination Therapy in Alzheimer's Disease: Comparison of Efficacy and Effectiveness Studies
  11. 41231
    “…Before incorporating personal genotyping into coursework, institutions should lead multi-disciplinary discussion to anticipate issues and incorporate teaching mechanisms that engage the ethical, legal, and social implications of personal genotyping, including addressing those found in this study, to go beyond what is offered by commercial providers.…”
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    Personal genome testing in medical education: student experiences with genotyping in the classroom
  12. 41232
    por Sarkar, Putul, Rasheed, Husham F
    Publicado 2013
    “…As there are important ethical and practical implications for intensive care clinicians while making decisions to provide ICU support to HIV-infected patients, a review of literature was undertaken. …”
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    Clinical review: Respiratory failure in HIV-infected patients - a changing picture
  13. 41233
    “…The chimpanzee remains the most physiological model to study the innate and adaptive immune responses, but its use is ethically difficult and is now very restricted and regulated. …”
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    Hepatitis C virus infection and related liver disease: the quest for the best animal model
  14. 41234
    “…AIM: We conducted this study to compare the extent and effectiveness of infraclavicular brachial plexus block achieved by injecting a local anesthetic drug after finding specific muscle action due to neural stimulator guided posterior cord stimulation and lateral cord/medial cord stimulation. METHODS: After ethical committee approval, patients were randomly assigned to one of the two study groups of 30 patients each. …”
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    Infraclavicular brachial plexus block: Comparison of posterior cord stimulation with lateral or medial cord stimulation, a prospective double blinded study
  15. 41235
    “…The trial was conducted in accordance with the good clinical practices (GCP) after obtaining ethical clearance from respective Institutional Review Boards. …”
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    To evaluate the efficacy and safety of “RV2427B” cream in Irritant dermatitis care
  16. 41236
    por Nakayama, Eri, Saijo, Masayuki
    Publicado 2013
    “…However, the NHP models have practical and ethical problems that limit their experimental use. …”
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    Animal models for Ebola and Marburg virus infections
  17. 41237
    “…Data extracted from these studies included type of journal, topic, characteristics of the search, methods of review including number of reviewers and method to achieve consensus between reviewers, inclusion and exclusion criteria, characteristics of the videos reported, ethical oversight, and follow-up. Results. Thirty-three studies were identified. …”
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    A systematic review of methods for studying consumer health YouTube videos, with implications for systematic reviews
  18. 41238
    “…The registry was piloted in six centres and following further fine tuning of the data sets, ethical committee submission and approval was completed. …”
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    Rationale and design of a UK database for a rare cancer type: the GEM Registry for gastrointestinal stromal tumours
  19. 41239
    “…Wider consideration of ethical issues emerging in these debates supports locally-held reasoning that paternal sickle cell testing should not be undertaken in this context, in contrast to views that testing should be done with or without the disclosure of misaligned paternity information. …”
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    Managing misaligned paternity findings in research including sickle cell disease screening in Kenya: ‘Consulting communities’ to inform policy()
  20. 41240
    por Muralidharan, Arjun, Smith, Maree T.
    Publicado 2013
    “…However, a major drawback of most rodent models of PCIBP is their short-term applicability due to ethical concerns. Thus, it has been difficult to gain insight into the mal(adaptive) neuroplastic changes occurring at multiple levels of the somatosensory system that likely contribute to intractable pain at the advanced stages of metastatic disease. …”
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    Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments
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