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  1. 42741
    “…METHODS AND MATERIALS: A study questionnaire was distributed among Saudi patients with type 2 DM who visited primary health care at Abha, Saudi Arabia, after obtaining an ethical approval. It was a modified questionnaire and included basic demographic characteristics of the patients, general knowledge and awareness of DM and DR, and their practices toward eye examination. …”
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    Awareness of diabetic retinopathy among patients with type-2 diabetes mellitus in Abha, Saudi Arabia: A survey-based research study
  2. 42742
    “…As a result, patients developing disease progression in phase I/II immunotherapy trials are generally seriously ill and are often treated off the trial for ethical consideration. Consequently, the happening of disease progression will terminate the toxicity event but not vice versa, so the issue of the semi‐competing risks arises. …”
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    SCI: A Bayesian adaptive phase I/II dose‐finding design accounting for semi‐competing risks outcomes for immunotherapy trials
  3. 42743
    “…Topics included 1) technological advancements in the in situ analysis of lung tissues, 2) new insights into stem cell signaling and plasticity in lung remodeling and regeneration, 3) the impact of extracellular matrix in stem cell regulation and airway engineering in lung regeneration, 4) differentiating and delivering stem cell therapeutics to the lung, 5) regeneration in response to viral infection, and 6) ethical development of cell-based treatments for lung diseases. …”
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    Stem cells, cell therapies, and bioengineering in lung biology and disease 2021
  4. 42744
    “…However, in vivo experiments for assessing the placental barrier permeability of chemicals is not ethically acceptable. Although ex vivo placental perfusion methods provide good alternatives for the assessment of placental barrier permeability, the application to a large number of test chemicals could be time- and resource-consuming. …”
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    Ensemble learning for predicting ex vivo human placental barrier permeability
  5. 42745
    “…Contact between wild animals and farmed livestock may result in disease transmission with huge financial, welfare and ethical consequences. Conflicts between people and wildlife can also arise when species such as wild boar (Sus scrofa) consume crops or dig up pasture. …”
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    Wild boar visits to commercial pig farms in southwest England: implications for disease transmission
  6. 42746
    “…Nationally recognized navigation competencies, related to developing a sensitivity to ethical, cultural, and professional issues, knowledge development, skills development, and practice-based learning, were identified and adapted. …”
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    Training cancer caregiver navigators: experiences from implementing the eSNAP and caregiver navigator intervention
  7. 42747
    “…The prospective study was carried out in May 2018 in multiple medical screening camps at hospitals, pharmacies, and public areas with the help of local health care workers under ethical guidelines. The volunteers took BP measurements using OMRON digital BP devices, in a seated position, and three successive readings were noted after 5 min rest. …”
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    May Measurement Month 2018: an analysis of blood pressure screening results from Pakistan( )
  8. 42748
    “…Accordingly, most of the participants hope that AI systems will primarily improve diagnosis confirmation, while they see their ethical and legal problems with regard to liability as the main obstacle to extensive clinical application. …”
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    The use and future perspective of Artificial Intelligence—A survey among German surgeons
  9. 42749
    “…From senior managers’ viewpoints, ethical issues of informed consent and resistance culture had the strongest links with challenges of learning analytic adoption in HEI; this was especially true for those institutions that had not adopted LA or who were in the initial phase of adoption (i.e., preparing for or partially implementing LA). …”
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    Untangling connections between challenges in the adoption of learning analytics in higher education
  10. 42750
    “…Sixty-four and 51 provided inclusion and exclusion criteria respectively. Ethical approval was reported in 51 and conflicts of interest in 34. …”
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    Quality of reporting of robot-assisted cholecystectomy in relation to the IDEAL recommendations: systematic review
  11. 42751
    “…Needed data to conduct these analyses should be collected unobtrusively. Finally, ethical principles must be respected, even though this may seem to conflict with goals of pragmatism; consent procedures could be incorporated in the flow of care.…”
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    Heterogeneity in pragmatic randomised trials: sources and management
  12. 42752
    “…Presented for describing additional unique features of supernumerary teeth and localized gigantism and ethical challenges in management.…”
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    Type II Pfieffer misdiagnosed as Crouzon syndrome with additional features of supernumerary teeth and localized symmetrical gigantism: a case report
  13. 42753
    “…RESULTS: The literature review included 34 relevant papers about approaches to patients leaving AMA: 8 case presentations, 4 ethical case analyses, 10 legal letters, 4 reviews and 8 original studies. …”
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    A step-by-step approach to patients leaving against medical advice (AMA) in the emergency department
  14. 42754
    “…Opaque value chains as well as environmental, ethical and health issues and food scandals are decreasing consumer trust in conventional agriculture and the dominant food system. …”
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    Exploring member trust in German community-supported agriculture: a multiple regression analysis
  15. 42755
    por Kliest, Tessa, Van Eijk, Ruben P.A., Al-Chalabi, Ammar, Albanese, Alberto, Andersen, Peter M., Amador, Maria Del Mar, BrÅthen, Geir, Brunaud-Danel, Veronique, Brylev, Lev, Camu, William, De Carvalho, Mamede, Cereda, Cristina, Cetin, Hakan, Chaverri, Delia, Chiò, Adriano, Corcia, Philippe, Couratier, Philippe, De Marchi, Fabiola, Desnuelle, Claude, Van Es, Michael A., Esteban, JesÚs, Filosto, Massimiliano, GarcÍa Redondo, Alberto, Grosskreutz, Julian, Hanemann, Clemens O., HolmØy, Trygve, HØyer, Helle, Ingre, Caroline, Koritnik, Blaz, Kuzma-Kozakiewicz, Magdalena, Lambert, Thomas, Leigh, Peter N., Lunetta, Christian, Mandrioli, Jessica, Mcdermott, Christopher J., Meyer, Thomas, Mora, Jesus S., Petri, Susanne, Povedano, MÓnica, Reviers, Evy, Riva, Nilo, Roes, Kit C.B., Rubio, Miguel Á., Salachas, FranÇois, Sarafov, Stayko, SorarÙ, Gianni, Stevic, Zorica, Svenstrup, Kirsten, MØller, Anette Torvin, Turner, Martin R., Van Damme, Philip, Van Leeuwen, Lucie A.G., Varona, Luis, VÁzquez Costa, Juan F., Weber, Markus, Hardiman, Orla, Van Den Berg, Leonard H.
    Publicado 2022
    “…Conducting studies on the effect of disease-modifying therapy in pediatric ALS may involve lengthy recruitment periods, high costs, ethical/legal implications, challenges in trial design and limited information.…”
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    Clinical trials in pediatric ALS: a TRICALS feasibility study
  16. 42756
    “…All the procedures obtained ethical approval in June 2021 (CEI-IB Ref No: IB4495/21PI). …”
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    Development and Evaluation of a Digital Health Intervention to Prevent Type 2 Diabetes in Primary Care: The PREDIABETEXT Study Protocol for a Randomised Clinical Trial
  17. 42757
    “…In this study, adult human neural stem cells (ahNSCs) derived from temporal lobe surgical samples were used (to avoid ethical and safety issues), and their therapeutic effects on ischemic stroke were examined using middle cerebral artery occlusion animal models. 5 × 10(5) ahNSCs was directly injected into the lateral ventricle of contralateral brain hemispheres of immune suppressed rat stroke models at the subacute phase of stroke. …”
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    JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models
  18. 42758
    “…However, many of these tools cannot be used in practice because they are embedded within variant prioritization algorithms, or exist as remote services that cannot be relied upon or are unacceptable because of legal/ethical barriers. In addition, many tools are not designed for command‐line usage, closed‐source, abandoned, or unavailable. …”
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    A pipeline‐friendly software tool for genome diagnostics to prioritize genes by matching patient symptoms to literature
  19. 42759
    “…Data analysis consisted of a qualitative directed content analysis using themes outlined from an international Delphi study of mental health clinicians and experts. Ethical approval was obtained from the Centre for Addiction and Mental Health and the University of Toronto. …”
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    “I think it's something that we should lean in to”: The use of OpenNotes in Canadian psychiatric care contexts by clinicians
  20. 42760
    “…However, collecting empirical data on violence is challenging due to ethical, safety, and data quality concerns. OBJECTIVE: This study estimated the anticipated effect of COVID-19 on violent discipline at home using multivariable predictive regression models. …”
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    Modelling the effect of the COVID-19 pandemic on violent discipline against children
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