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  1. 46401
    “…The study was approved by the institutional ethical review committee i.e. advanced studies and research board (ASRB). …”
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    Role of multi-strain probiotics in preventing severity and frequency of recurrent respiratory tract infections in children
  2. 46402
    “…These contribute to transgender individuals having poorer health than cis individuals, i.e. individuals whose sex assigned at birth is in line with their gender identity. It is an ethical duty to take effective measures to minimize inequalities in medical care. …”
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    Why do transgender individuals experience discrimination in healthcare and thereby limited access to healthcare? An interview study exploring the perspective of German transgender individuals
  3. 46403
    “…An organized community structure stems from a shared ethical understanding of humanity as being interconnected with each other and the environment. …”
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    From disease- to people-centred pandemic management: organized communities, community-oriented primary care and health information systems
  4. 46404
    “…METHODS: This was a retrospective cross-sectional study conducted at a tertiary care hospital in Karachi between 1 January 2021 and 31 December 2021, following approval from the hospital ethical review committee. Patients above the age of 15 who underwent CT scans were included, while individuals with a history of cervical trauma, infection, rheumatoid arthritis, or congenital anomalies, as well as those younger than 15 years old, were excluded. …”
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    Three-dimensional computed tomography analysis of the atlanto-dental interval in a healthy Karachi population: a single-center retrospective cross-sectional study
  5. 46405
    “…The AMYPAD-PNHS (EudraCT: 2018–002277-22) was approved by the ethical review board of the VU Medical Center (VUmc) as the Sponsor site and in every affiliated site. …”
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    Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study
  6. 46406
    “…Stem cell therapy has proven effective in addressing cellular senescence, however, it still has issues such as immune rejection and ethical concerns. Microvesicles (MVs) constitute the primary mechanism through which stem cell therapy exerts its effects, offering a cell-free approach that circumvents these risks and has excellent anti-ageing potential. …”
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    Microvesicles-hydrogel breaks the cycle of cellular senescence by improving mitochondrial function to treat osteoarthritis
  7. 46407
    “…The protocol was approved by the Ethical Committee. ESS was confirmed histopathologically in 34 women, but follow-up data were available in only 31 women. …”
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    Clinical study investigating the role of lymphadenectomy, surgical castration and adjuvant hormonal treatment in endometrial stromal sarcoma
  8. 46408
    “…Because data management and the use of electronic data capture systems in clinical trials are characterized by the impact of regulations and guidelines, ethical concerns are discussed. In this context quality management becomes an important part of compliant data management. …”
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    Heterogeneity prevails: the state of clinical trial data management in Europe - results of a survey of ECRIN centres
  9. 46409
    “…Isolation of MSCs from the umbilical cord also presents little, if any, ethical concerns, and the process of obtaining the cord tissue is relatively simple with appropriate consent from the donor. …”
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    Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton’s jelly derived mesenchymal stem cells? A comparative study
  10. 46410
    “…All measurements will be performed at T0 and at the end of training/control period (T1). For ethical reasons, after this first phase infants enrolled in the control group will perform the CareToy training, while the training group will continue standard care. …”
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    Home-based, early intervention with mechatronic toys for preterm infants at risk of neurodevelopmental disorders (CARETOY): a RCT protocol
  11. 46411
    “…Provision of tenofovir gel to the women from the CAPRISA 004 trial meets the ethical obligation for post-trial access, and helps identify a potential avenue for future scale-up of microbicides within the public health system of South Africa. …”
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    Assessing the implementation effectiveness and safety of 1% tenofovir gel provision through family planning services in KwaZulu-Natal, South Africa: study protocol for an open-label randomized controlled trial
  12. 46412
    por McMurray, John, Packer, Milton, Desai, Akshay, Gong, Jianjian, Greenlaw, Nicola, Lefkowitz, Martin, Rizkala, Adel, Shi, Victor, Rouleau, Jean, Solomon, Scott, Swedberg, Karl, Zile, Michael R., Andersen, Karl, Arango, Juan Luis, Arnold, Malcolm, Be˘lohlávek, Jan, Böhm, Michael, Boytsov, Sergey, Burgess, Lesley, Cabrera, Walter, Chen, Chen-Huan, Erglis, Andrejs, Fu, Michael, Gomez, Efrain, Gonzalez, Angel, Hagege, Albert-Alain, Katova, Tzvetana, Kiatchoosakun, Songsak, Kim, Kee-Sik, Bayram, Edmundo, Martinez, Felipe, Merkely, Bela, Mendoza, Iván, Mosterd, Arend, Negrusz-Kawecka, Marta, Peuhkurinen, Keijo, Ramires, Felix, Refsgaard, Jens, Senni, Michele, Sibulo, Antonio S., Silva-Cardoso, José, Squire, Iain, Starling, Randall C., Vinereanu, Dragos, Teerlink, John R., Wong, Raymond
    Publicado 2015
    “…AIMS: Although active-controlled trials with renin–angiotensin inhibitors are ethically mandated in heart failure with reduced ejection fraction, clinicians and regulators often want to know how the experimental therapy would perform compared with placebo. …”
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    A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure
  13. 46413
    “…The tool was then evaluated in a pilot clinical evaluation in Tygerberg Hospital, Cape Town. RESULTS: After ethical approval and informed consent, 37 nurses and midwives evaluated the tool. …”
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    Usability and Feasibility of PIERS on the Move: An mHealth App for Pre-Eclampsia Triage
  14. 46414
    “…This study has been approved by The Regional Scientific Ethical Committees for Southern Denmark, S-20110109. …”
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    Impact of a magnetic resonance imaging-guided treat-to-target strategy on disease activity and progression in patients with rheumatoid arthritis (the IMAGINE-RA trial): study protocol for a randomized controlled trial
  15. 46415
    “…DISCUSSION: Following funding by the Canadian Institutes of Health Research and local ethical approvals, site enrollment started in 2010 and was closed in February 2014. …”
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    Evaluating processes of care and outcomes of children in hospital (EPOCH): study protocol for a randomized controlled trial
  16. 46416
    “…TRIAL REGISTRATION: ClinicalTrial.gov: ID: NCT01884948, registered June 14, 2013; Institution Ethical Board Approval: KEK-ZH-Nr. 2010–0038; Swissmedic Notification: 2012DR3215.…”
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    “A randomized, double-blind study of the effects of omega-3 fatty acids (Omegaven™) on outcome after major liver resection”
  17. 46417
    “…University of Ghana, Medical School Ethical and Protocol Review Committee: MS-Et/M.8–P4.1/2014-2015 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13063-015-1111-5) contains supplementary material, which is available to authorized users.…”
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    Uterine Tonus Assessment by Midwives versus Patient self-assessment in the active management of the third stage of labor (UTAMP): study protocol for a randomized controlled trial
  18. 46418
    “…Seat belts eliminated the risk of falling from an upright chair and reduced head impact forces in sideways wheelchair tips in this study; however, their use must be considered within the ethical and legal definitions of restraints.…”
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    The dynamics of electric powered wheelchair sideways tips and falls: experimental and computational analysis of impact forces and injury
  19. 46419
    “…BiBBS will test interventions using the Trials within Cohorts (TwiCs) approach and other quasi-experimental designs where TwiCs are neither feasible nor ethical, to evaluate these early life interventions. …”
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    Born in Bradford’s Better Start: an experimental birth cohort study to evaluate the impact of early life interventions
  20. 46420
    “…METHODS/DESIGN: This is a 1:1 randomised controlled trial comparing two suture techniques for the closure of the midline abdominal wound following surgery for colorectal cancer. Full ethical approval has been gained (Wales REC 3, MREC 12/WA/0374). …”
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    Hughes Abdominal Repair Trial (HART) – Abdominal wall closure techniques to reduce the incidence of incisional hernias: study protocol for a randomised controlled trial
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