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46641por Hill, Cian J., Brown, Jillian R. M., Lynch, Denise B., Jeffery, Ian B., Ryan, C. Anthony, Ross, R. Paul, Stanton, Catherine, O’Toole, Paul W.“…Investigating the faecal microbiota is widely used as a non-invasive and ethically simple proxy for intestinal biopsies. There is an urgent need for collection and transport media that would allow faecal sampling at distance from the processing laboratory, obviating the need for same-day DNA extraction recommended by previous studies of freezing and processing methods for stool. …”
Publicado 2016
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46642“…Despite the importance of RIs, globally there are very few publications on RIs for neonatal TFTs primarily due to ethical and technical issues surrounding recruitment of neonates for a prospective study. …”
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46643“…TRIAL REGISTRATION: ClinicalTrials NCT00850629, first registration 17 February 2009, verified January 2012, Paediatric part of the interventional study. Ethic proposal approved at 08.04.2009 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s40608-016-0110-8) contains supplementary material, which is available to authorized users.…”
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46644por Verdonk, Franck, Roux, Pascal, Flamant, Patricia, Fiette, Laurence, Bozza, Fernando A., Simard, Sébastien, Lemaire, Marc, Plaud, Benoit, Shorte, Spencer L., Sharshar, Tarek, Chrétien, Fabrice, Danckaert, Anne“…Moreover, this new experimental approach will provide a support not only to neuropathological diagnosis but also to study microglial function in various disease models while reducing the number of animals needed to approach the international ethical statements. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12974-016-0614-7) contains supplementary material, which is available to authorized users.…”
Publicado 2016
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46645por Søreide, Kjetil, Watson, Martin M., Lea, Dordi, Nordgård, Oddmund, Søreide, Jon Arne, Hagland, Hanne R.“…Immune-cell characteristics are being performed by IHC and flow cytometry in tumour and peripheral blood samples. The project has ethical approval (REK Helse Vest, #2012/742), is financially supported with a Ph.D.…”
Publicado 2016
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46646“…BACKGROUND: The ethical argument that shared decision-making is “the right” thing to do, however laudable, is unlikely to change how healthcare is organized, just as evidence alone will be an insufficient factor: practice change is governed by factors such as cost, profit margin, quality, and efficiency. …”
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46647“…We used data on gestational age, birth weight, Apgar score, time between admission and birth, use of corticosteroids and maternal and foetal survival. Ethical clearance was obtained from the directorate of research and publications of the University of Dodoma (ref. …”
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46648por Baeten, Jared M., Heffron, Renee, Kidoguchi, Lara, Mugo, Nelly R., Katabira, Elly, Bukusi, Elizabeth A., Asiimwe, Stephen, Haberer, Jessica E., Morton, Jennifer, Ngure, Kenneth, Bulya, Nulu, Odoyo, Josephine, Tindimwebwa, Edna, Hendrix, Craig, Marzinke, Mark A., Ware, Norma C., Wyatt, Monique A., Morrison, Susan, Haugen, Harald, Mujugira, Andrew, Donnell, Deborah, Celum, Connie“…The use of a non-concurrent comparison of HIV-1 incidence is a potential limitation of this approach; however, it would not have been ethical to enroll a contemporaneous population not provided access to ART and PrEP. …”
Publicado 2016
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46649“…In the test group, the crestal tissue thickness dropped from 2.20 mm ± 0.48 SD at baseline to 0.9 mm ± 1.02 SD at reentry, whereas crestal mucosa in the control group showed higher stability (2.64 mm ± 0.48 SD at baseline to 2.62 mm ± 0.61 SD at reentry). For ethical reasons, the test group was terminated after 10 cases, and the remaining cases were finished within the control group. …”
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46650por Roy, Ashutosh, Singh, Amandeep, Sidhu, Darshan Singh, Jindal, RP, Malhotra, Mishi, Kaur, Haramritpal“…MATERIALS AND METHODS: With Institutional Ethical Committee approval, this study was conducted on 100 patients having LUTS and BPH after obtaining written informed consent. …”
Publicado 2016
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46651por Nishida, Yasuhiro, Maruyama, Satoshi, Shouji, Ichiro, Kemuriyama, Takehito, Tashiro, Akimasa, Ohta, Hiroyuki, Hagisawa, Kohsue, Hiruma, Megumi, Yokoe, Hidetake“…Because the issue involves humans during flight, the effects on humans themselves are clearly of great importance, but ethical considerations largely preclude any research on the human body that probes to any depth the endogenous physiological states and functions. …”
Publicado 2016
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46652por Smit, Kirsten F., Brevoord, Daniel, De Hert, Stefan, de Mol, Bas A., Kerindongo, Raphaela P., van Dieren, Susan, Schlack, Wolfgang S., Hollmann, Markus W., Weber, Nina C., Preckel, Benedikt“…We hypothesized that helium induces pre- and postconditioning in CABG-patients, affecting signaling molecules protein kinase C-epsilon (PKC-ε), p38 mitogen activated protein kinase (p38 MAPK), extracellular signal-regulated kinase 1/2 (ERK-1/2) and heat shock protein 27 (HSP-27) within cardiac tissue, and reducing postoperative troponin levels. METHODS: After ethical approval and informed consent, 125 elective patients undergoing CABG surgery were randomised into this prospective, placebo controlled, investigator blinded, parallel arm single-centre study. …”
Publicado 2016
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46653por Eldridge, Sandra M, Chan, Claire L, Campbell, Michael J, Bond, Christine M, Hopewell, Sally, Thabane, Lehana, Lancaster, Gillian A“…The new items cover how participants were identified and consent obtained; if applicable, the prespecified criteria used to judge whether or how to proceed with a future definitive RCT; if relevant, other important unintended consequences; implications for progression from pilot to future definitive RCT, including any proposed amendments; and ethical approval or approval by a research review committee confirmed with a reference number. …”
Publicado 2016
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46654por Shabbir, Asma, Mirza, Talat, Khalid, Abdullah Bin, Qureshi, Muhammad Asif, Asim, Sadaf Ahmed“…METHODS: A total of 95 patients who underwent colonoscopic biopsy or colectomy were studied after Institutional Ethical Approval. Hematoxylin & eosin (H&E) staining was performed on all the tissue sections. …”
Publicado 2016
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46655“…Six main themes were derived from the included articles: 1-the frequency of pharmaceutical representatives’ visits, 2-the perceived ethical acceptability of the interactions between pharmaceutical representatives and physicians, 3-the attitudes held by physicians towards visits by pharmaceutical representatives, 4-their perception of the effect of such visits on prescription patterns, 5-reasons to accept or reject pharmaceutical representatives, and lastly, 6-guidelines. …”
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46656por Ozolina, Agnese, Sarkele, Marina, Sabelnikovs, Olegs, Skesters, Andrejs, Jaunalksne, Inta, Serova, Jelena, Ievins, Talis, Bjertnaes, Lars J., Vanags, Indulis“…MATERIALS AND METHODS: We performed an ethically approved prospective observational pilot study. …”
Publicado 2016
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46657“…That most animal research undergoes peer review or ethical review would offer the possibility to detect risks of bias at an earlier stage, before the research has been conducted. …”
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46658“…Odds Ratios (OR) with 95% Confidence Intervals (CIs) were calculated and the analyses were carried out by the RevMan 5.3 software. Ethical approval was not necessary for this type of study. …”
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46659por Eldridge, Sandra M., Chan, Claire L., Campbell, Michael J., Bond, Christine M., Hopewell, Sally, Thabane, Lehana, Lancaster, Gillian A.“…The new items cover how participants were identified and consent obtained; if applicable, the prespecified criteria used to judge whether or how to proceed with a future definitive RCT; if relevant, other important unintended consequences; implications for progression from pilot to future definitive RCT, including any proposed amendments; and ethical approval or approval by a research review committee confirmed with a reference number. …”
Publicado 2016
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46660por Wongcharoen, Wanwarang, Sutthiwutthichai, Satjatham, Gunaparn, Siriluck, Phrommintikul, Arintaya“…BACKGROUND: It has recently been shown that non-high density lipoprotein cholesterol (non-HDL-C) may be a better predictor of cardiovascular risk than low density lipoprotein cholesterol (LDL-C). Based on known ethic differences in lipid parameters and cardiovascular risk prediction, we sought to study the predictability of attaining non-HDL-C target and long-term major adverse cardiovascular event (MACE) in Thai patients after acute myocardial infarction (AMI) compared to attaining LDL-C target. …”
Publicado 2017
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