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  1. 8661
  2. 8662
    por Simalatsar, Alena
    Publicado 2023
    “…Clinical trials and tests on animals initiate a cyclic procedure that may involve multiple redesigns and retesting, which typically takes two or three years for medical devices and up to eight years for novel medicines, and costs between 10 and 20 million euros. The US Food and Drug Administration (FDA) acknowledges that for many novel devices, practical limitations require alternative approaches, such as computer modeling and engineering tests, to conduct large, randomized studies. …”
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  3. 8663
    “…The final calculation of the costs is expressed in absolute values in euros as the percentage of the gross domestic product per capita and in international dollars (I$). …”
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  4. 8664
    “…Considering this cost and the current epidemiological data on respiratory infections in France, the absence of valuation for outpatient care represents an annual loss of over 17 million euros for healthcare facilities. CONCLUSION: Micro-costing is a key element in valuing healthcare costs. …”
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  5. 8665
  6. 8666
  7. 8667
  8. 8668
    “…The estimated additional costs of lost workdays due to the incidence were 1.8–2.1 million euros. CONCLUSIONS: The prevalence of sickness absences among public sector employees residing in affected areas increased shortly after drinking water distribution system was contaminated, but no long-term effects were observed. …”
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  9. 8669
    “…MAIN OUTCOME MEASURES: The net contribution of smoking versus non-smoking individuals to public finance balance (euros). RESULTS: Smoking was associated with a greater mean annual healthcare cost of €1600 per living individual during follow-up. …”
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  10. 8670
    “…Mean annual global cost per patient was 68448 +/-33374 Euros and increased with EDSS (r = 0.644), utility (r = -0.456) and IPA (r = 0.519-0.671) worsening. …”
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  11. 8671
    “…CONCLUSIONS: The protocol for administering parenteral medication is still not implemented completely, therefore an investment in time and Euros is needed.…”
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  12. 8672
  13. 8673
    “…METHODS: Based on interviews with the involved staff, multiple databases and stored records from the Infection Prevention Division all actions undertaken, extra staff employment, use of resources, bed-occupancy rates, and other miscellaneous cost drivers during different outbreaks were scored and quantified into Euros. This led to total costs per outbreak and an estimated average cost per positive patient per outbreak day. …”
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  14. 8674
    “…Drug costs were calculated and converted into Euros (€ 1 = N.kr 7.4540). RESULTS: Drugs for the treatment of ADHD was significantly more often prescribed in northern Norway than in any other Norwegian health region (P < 0.001). …”
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  15. 8675
  16. 8676
    “…Total hospitalizations costs increased from 602 to 678 millions euros (+12.6 %). Pneumonia-related mortality increased (+37.2 %). …”
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  17. 8677
    “…If we use the 0.3 threshold for economic simulation, 43% of ALND could be avoided, reducing the costs of caring by 1 051 980 EUROS among the 1036 patients. CONCLUSION: We demonstrated the cost-effectiveness of using the MSKCC NSN prediction nomogram by avoiding ALND for the pN0(i+) or pN1(mic) ER+ HER2- breast cancer patients with a MSKCC score of less than or equal to 0.3.…”
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  18. 8678
    “…The causal agent of root and butt rot of conifer trees, Heterobasidion annosum, is widespread in boreal forests and economically responsible for annual loss of approximately 50 million euros to forest industries in Finland alone and much more at European level. …”
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  19. 8679
    “…OUTCOMES MEASURES: Of primary interest is the effect of district-level measures of rurality, physician density and multiple deprivation on (1) the proportion of patients with general practitioner (GP) coordination of specialist care and (2) the mean amount in Euros claimed by specialist physicians. RESULTS: The proportion of patients whose use of specialist services was coordinated by a GP was significantly higher in rural areas and in highly deprived regions, as compared with urban and less deprived regions. …”
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  20. 8680
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