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  1. 1341
    “…The reduction of tumor size is in accordance with the holistic view that many types of cancer are caused by emotional and existential disturbances. From a holistic perspective, cancer can be understood as a simple disturbance of the cells, arising from the tissue holding on to a trauma with strong emotional content. …”
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    Clinical Holistic Medicine: Induction of Spontaneous Remission of Cancer by Recovery of the Human Character and the Purpose of Life (the Life Mission)
  2. 1342
    “…Consultations were on existential and relational issues, loss, grief and identity were main themes. …”
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    Strengthening the spiritual domain in palliative care through a listening consultation service by spiritual caregivers in Dutch PaTz-groups: an evaluation study
  3. 1343
    “…PPI caused considerations related to emotional (sadness/sorrow and existential thoughts), administrative (e.g. arranging meetings, balancing work and small talk) and intellectual (e.g. avoiding information harm, continuing activities despite the death of patients) investments. …”
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    The impact of patient involvement in research: a case study of the planning, conduct and dissemination of a clinical, controlled trial
  4. 1344
    “…The study was part of a longitudinal study, and three former interviews helped build trusting relationships with participants and focus the semi-structured interview guide. An existential theory of well-being and suffering considering health to be a balancing of mobility and dwelling was applied. …”
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    Being active 1½ years after hip fracture: a qualitative interview study of aged adults’ experiences of meaningfulness
  5. 1345
    “…IMPORTANCE: The coronavirus disease 2019 (COVID-19) pandemic poses an existential threat to many US residential colleges; either they open their doors to students in September or they risk serious financial consequences. …”
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    Assessment of SARS-CoV-2 Screening Strategies to Permit the Safe Reopening of College Campuses in the United States
  6. 1346
    “…METHODS: We conducted a survey among a representative sample of 32,477 Dutch citizens aged 55+, comprising questions about health, existential issues and the nature of the death wish. …”
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    Prevalence and characteristics of older adults with a persistent death wish without severe illness: a large cross-sectional survey
  7. 1347
    “…Interdisciplinary teams provide a diagnostic workup of neurological, psychiatric, and existential injuries, and from these assessments, individualized care plans are developed. …”
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    Efficacy of an Interdisciplinary Intensive Outpatient Program in Treating Combat-Related Traumatic Brain Injury and Psychological Health Conditions
  8. 1348
    “…Module I: The HPCTs’ SCC evaluation, understanding the major concepts of spiritual care and logotherapy; Modules II-IV: Meaning-centered interventions (MCIs) related to spiritual needs (existential, relational, and transcendental/religious); Module V: The process of meaning-centered spiritual care. …”
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    A meaning-centered spiritual care training program for hospice palliative care teams in South Korea: development and preliminary evaluation
  9. 1349
    “…OBJECTIVE: There is a common clinical observation that experiencing chronic pain often requires a revision of life goals and expectations, and hence, it impacts the existential domain including one’s perception of the meaning in life (MiL). …”
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    Meaning in Life Among Patients With Chronic Pain and Suicidal Ideation: Mixed Methods Study
  10. 1350
    “…Hence, health care must address the fact that mothers are dependent on their immediate social environment and that this dependency interacts with their health and suffering on an existential level.…”
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    Health and suffering are associated with social support: a cross-sectional study of women and mothers with exhaustion and pain
  11. 1351
    “…CONCLUSION: This study provides evidence for referring more COPD patients to SPC, which is more focused on symptom management and psychosocial and existential support.…”
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    Benefits, for patients with late stage chronic obstructive pulmonary disease, of being cared for in specialized palliative care compared to hospital. A nationwide register study
  12. 1352
    “…The reproducibility crisis (or replication crisis) in biomedical research is a particularly existential and under-addressed issue in the field of behavioral neuroscience, where, in spite of efforts to standardize testing and assay protocols, several known and unknown sources of confounding environmental factors add to variance. …”
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    Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives
  13. 1353
    “…From extracted data, we identified seven themes: (1) disconnection and emptiness: a “haunting alienation”, (2) alienation arising from childhood experiences, (3) thwarted desire for closeness and connection, (4) paradox: for both closeness and distance, (5) experiences of existential loneliness, (6) recovery, embedded in a social world, and (7) group therapy: a setback. …”
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    The experience of loneliness among people with a “personality disorder” diagnosis or traits: a qualitative meta-synthesis
  14. 1354
    “…Goals of care (31%), insight (28%) and psychosocial/existential issues (27%) were commonly explored. CONCLUSIONS: This study highlights the burden of symptoms in a cohort of ambulatory palliative care patients and the opportunity such services can provide for education, psychosocial care and future planning. …”
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    Impact of ambulatory palliative care on symptoms and service outcomes in cancer patients: a retrospective cohort study
  15. 1355
    “…Six dimensions of older adults’ vulnerability were identified: physical; psychological; relational/interpersonal; moral; sociocultural, political, and economic; and existential/spiritual. This analysis suggested three ways to relate to older adults’ vulnerability: understanding older adults’ vulnerability, taking care of vulnerable older adults, and intervening through socio-political-economic measures. …”
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    The concept of vulnerability in aged care: a systematic review of argument-based ethics literature
  16. 1356
    “…BACKGROUND: Kidney transplantation is the best treatment for kidney failure but is associated with medical, psychological, and existential challenges for patients. Patients’ experiential knowledge can help other patients facing these challenges. …”
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    Perspectives of Kidney Transplant Recipients, Transplant Candidates, and Living Kidney Donors on the Role of Patients’ Self-Narratives and Experiences of Creative Writing Workshops: A Qualitative Study
  17. 1357
    “…BACKGROUND AND AIMS: Healthcare workers (HCWs) throughout the world have been exposed to economic and existential stress during the Covid-19 pandemic. The American Medical Association (AMA) has documented that increased healthcare burden correlates with increased stress, burnout, and psychological burden in HCWs. …”
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    Use of virtual meeting and survey technology to assess Covid-19-related mental well-being of healthcare workers
  18. 1358
    “…Few studies have included the self-reporting of existential or spiritual concerns, emotions, and well-being. …”
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    Advantages and Challenges of Using Telehealth for Home-Based Palliative Care: Systematic Mixed Studies Review
  19. 1359
    “…The prevalence of high symptom burden, severe pain, functional impairment, socio-familial risk, existential/spiritual problems, 6-month mortality and in-hospital death was significantly higher (p < 0.001) at the high complexity levels in both scoring systems. …”
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    Validation Study of the PALCOM Scale of Complexity of Palliative Care Needs: A Cohort Study in Advanced Cancer Patients
  20. 1360
    “…The primary reason why protein misfolding represents an existential threat to the cell is the propensity of incorrectly folded proteins to aggregate, thus causing a global perturbation of the crowded and delicate intracellular folding environment(1). …”
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    4D Imaging of Protein Aggregation in Live Cells
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