“…In this study, we characterized a group of monoclonal antibodies isolated from HIV-1 infected donors (V2i MAbs) that displayed characteristics of CD4i antibodies. Binding experiments demonstrated that the V2i MAbs preferentially recognize CD4-bound open Env trimers. …”
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“…We explored the optimal growth conditions, chromosome morphology, and number and transfection experiment of JFSP cells in vitro. The susceptibility of JFSP cells to different viruses, including Bohle virus (BIV), Viral hemorrhagic septicemia virus (VHSV), Hirame rhabdovirus (HIRRV), Infectious hematopoietic necrosis virus (IHNV), and Lymphocystis disease virus (LCDV) and the expression changes of immune-related genes after virus infection were detected. …”
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“…After treatment with CYA, the expression of pyroptosis-related proteins in the ovarian GCs of mice was significantly lower than that in PCOS mice. In vitro experiments showed that CYA could ameliorate KGN cells’ pyroptosis by alleviating the activation of the IRE1α signaling pathway. …”
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“…Thus, a laboratory microcosm experiment was performed to explore the mixed-litter effects of fresh leaf, semi-decomposed leaf and fine root on the soil enzyme activity and microbial community in an evergreen broadleaf karst forest in Southwest China. …”
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“…CONCLUSION: In summary, we showed that CPS is the core drug combination for treating H. pylori infection. Animal experiments demonstrated that CPS has bacteriostatic properties and can reduce the release of inflammatory cytokines in the gastric mucosa. …”
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“…Besides, the correlation between PD-L1 expression and KRAS/TP53 mutation status were also investigated by using TCGA data analysis. In vitro experiments were used to explore the mechanism underlying KRAS- and TP53-related PD-L1 expression. …”
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“…The UC model was established in mice, and the results of network pharmacology and molecular docking were verified by in vivo experiments. In all, 5 compounds were obtained from the TCMSP database, and 74 UC-related pathogenic genes were obtained from GeneCards, DisGeNET, OMIM, TTD, and DrugBank. …”
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“…Gain‐of and loss‐of‐function assays were conducted both in vitro and in vivo along with the rescue experiment, for revealing the relative genes' functions in HCC progress. …”
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“…Multilayer diffraction can be observed when a diffraction experiment is performed on nanocrystals packed with a periodic arrangement. …”
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“…In recent years, the mechanisms of plant salt tolerance have received extensive attention from researchers. In this paper, an experiment was implemented to assess the potential effect of different NaCl and NaHCO(3) (sodium bicarbonate—an alkaline salt) concentrations (25 mmol·L(−1), 50 mmol·L(−1), 100 mmol·L(−1), 150 mmol·L(−1) and 200 mmol·L(−1)) on the growth, antioxidant enzymes, osmoprotectants, photosynthetic pigments and MDA of Viola tricolor L. to reveal the physiological response and explore the maximum concentrations of NaCl and NaHCO(3) stress that V. tricolor can tolerate. …”
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“…In contrast to the first experiment, the majority of the proteins that differed from wild-type were downregulated in the sciatic nerve crush group. …”
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“…We also investigated whether intensive grazing by cattle and lama in Puna grasslands may reduce the presence of AMF in these highly disturbed soils, driving or not major ecological changes, but no consistent results were found, suggesting that more specific experiments and further investigations may address the question more specifically. …”
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“…Further functional experiments revealed that IDE attenuated cell viability injury, apoptosis, oxidative stress, and inflammatory damage in LPS-induced hepatocytes via RAGE/p38 signaling. …”
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“…Additionally, various resistance genes were identified in its genome, including bla(NDM-1), bla(OXA-10), bla(PER-4), aph(3′)-VI, ant(2′′)-Ia, ant(3′)-Ia, sul1, catB8, catA1, mph(E), and tet. Conjugation experiments and whole-genome sequencing revealed that the bla(NDM-1) gene could be transferred to the transconjugant via the formation of pJ18004577_NDM, a novel hybrid plasmid. …”
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“…The results of our experiment and various bioinformatics approaches validated that PROS1 was a valuable poor prognostic marker. …”
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“…This study suggests more experiments are needed to evaluate additional strains of PPIV1 and their potential to cause respiratory disease in swine. …”
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“…This species also differs from the other two species in that it pupates in an above-ground pouch made of leaves by spinning with course silk. In the predation experiment using lizards as one of the potential predators, pupae of all three species were repelled, and repeated biting of pupae increased the lizard’s tendency to avoid them. …”
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“…Data from 13 articles (14 experiments) met the selection criteria for inclusion in the meta-analysis, and 48 treatment means were used for the analysis. …”
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“…The facial mechanical withdrawal threshold was daily measured during the whole experiment. The behavioral changes (ipsilateral and bilateral face grooming behavior) in a plastic cage of rats were observed and recorded. …”
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