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535141“…Chromatin immunoprecipitation experiments highlight that Ldb1 likely imparts control on Pdx1 levels through occupation of the Pdx1 Area I-II regulatory domains. …”
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535142por Gao, Jiping, Zhao, Yanze, Zhang, Wenzhong, Sui, Yanghui, Jin, Dandan, Xin, Wei, Yi, Jun, He, Dawei“…The biochar was applied to paddy soil at three rates (0, 0.7, and 2.1%, w/w), with or without N fertilization (0, 168, and 210 kg N ha(–1)). Pot experiments were performed to determine nitrous oxide (N(2)O) emissions and (15)N recovery from paddy soil using a (15)N tracer across the rice growing season. …”
Publicado 2019
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535143por Meier, Alexandra, de Laat, Melody, Pollitt, Christopher, Walsh, Donald, McGree, James, Reiche, Dania B., von Salis-Soglio, Marcella, Wells-Smith, Luke, Mengeler, Ulrich, Mesa Salas, Daniel, Droegemueller, Susanne, Sillence, Martin N.“…First, a prototype method was developed during the detailed observation of 37 ponies undergoing a laminitis induction experiment. The final method was refined and validated using video footage taken during the induction study and from a clinical trial of naturally occurring endocrinopathic laminitis cases. …”
Publicado 2019
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535144por Wagner, Sabine G., Mähler, Christoph, Polte, Ingmar, von Poschinger, Jeremy, Löwe, Hannes, Kremling, Andreas, Pflüger-Grau, Katharina“…The design of the dosing unit enables the user to perform experiments with up to four different growth rates in parallel (each measured in triplicates) per EV3-block used. …”
Publicado 2019
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535145por Contarini, Gabriella, Franceschini, Davide, Facci, Laura, Barbierato, Massimo, Giusti, Pietro, Zusso, Morena“…RESULTS: Vehicle-MOG(35-55)-immunized (MOG(35-55)) mice developed ascending paralysis which peaked several days later and persisted until the end of the experiment. PEALut, given intraperitoneally daily starting on day 11 post-immunization, dose-dependently improved clinical score over the range 0.1–5 mg/kg. …”
Publicado 2019
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535146por Kiener, Mirjam, Chen, Lanpeng, Krebs, Markus, Grosjean, Joël, Klima, Irena, Kalogirou, Charis, Riedmiller, Hubertus, Kneitz, Burkhard, Thalmann, George N., Snaar-Jagalska, Ewa, Spahn, Martin, Kruithof-de Julio, Marianna, Zoni, Eugenio“…The functional role of miR-221-5p was characterised in androgen- dependent and androgen- independent PCa cell line models (C4–2 and PC-3M-Pro4 cells) by miR-221-5p overexpression and knock-down experiments. The metastatic potential of highly aggressive PC-3M-Pro4 cells overexpressing miR-221-5p was determined by studying extravasation in a zebrafish model. …”
Publicado 2019
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535147por Zhang, Yan-Zhen, Yao, Jian-Ning, Zhang, Lian-Feng, Wang, Chun-Feng, Zhang, Xue-Xiu, Gao, Bing“…RESULTS: Compared with the normal mice, the expression level of NLRC5 increased significantly (P < 0.01) in the fibrosis group, but decreased significantly in the recovery group (P < 0.01). In in vitro experiments, the content of NLRC5 was enhanced after TGF-β1 stimulation and decreased to a lower level when treated with MDI (P < 0.01). …”
Publicado 2019
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535148por García-Vázquez, Verónica, von Haxthausen, Felix, Jäckle, Sonja, Schumann, Christian, Kuhlemann, Ivo, Bouchagiar, Juljan, Höfer, Anna-Catharina, Matysiak, Florian, Hüttmann, Gereon, Goltz, Jan Peter, Kleemann, Markus, Ernst, Floris, Horn, Marco“…This article describes the current prototype developed in this project and the experiments conducted to evaluate it. METHODS: The current approach of the Nav EVAR project is guiding EVAR interventions in real-time with an electromagnetic tracking system after attaching a sensor on the catheter tip and displaying this information on Microsoft HoloLens glasses. …”
Publicado 2018
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535149por Richter, Christin, Marquardt, Stephan, Li, Fanghua, Spitschak, Alf, Murr, Nico, Edelhäuser, Berdien A. H., Iliakis, George, Pützer, Brigitte M., Logotheti, Stella“…MIR888-dependent inhibition of APLF by E2F1 was demonstrated using overexpression and knockdown experiments, in combination with luciferase assays. …”
Publicado 2019
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535150“…We developed a list of components and used animations as well as video clips of patients discussing their experiences of participation, matched to these components. …”
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535151“…We also conducted a qualitative exploratory substudy of eight married women and eight married men who were subscribers to and accessed the service during this time to understand their experiences. We interviewed 11 doctors from the same service who provided phone consultations to subscribers. …”
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535152por Wang, Yingying, Guo, Baosen, Xiao, Zengrong, Lin, Haijun, Zhang, Xi, Song, Yueqiang, Li, Yalei, Gao, Xuehu, Yu, Jinjun, Shao, Zhihua, Li, Xuekun, Luo, Yuping, Li, Siguang“…Then loss-of-function experiments in human PSCs were performed to investigate the function of these candidate lncRNAs. …”
Publicado 2019
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535153por Burdick Sanchez, Nicole C., Carroll, Jeffery A., Corley, Jimmie R., Broadway, Paul R., Callaway, Todd R.“…The objective of this experiment was to evaluate the performance and hematological responses of weaned pigs supplemented with yeast cell wall (YCW) when challenged orally with Salmonella Typhimurium. …”
Publicado 2019
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535154por Singh, Udai B., Malviya, Deepti, Singh, Shailendra, Kumar, Manoj, Sahu, Pramod K., Singh, H. V., Kumar, Sunil, Roy, Manish, Imran, Mohd., Rai, Jai P., Sharma, A. K., Saxena, A. K.“…To assess the effect of MeJA (150 mg L(–1)) in combination with the biocontrol agent T. harzianum UBSTH-501 in vivo, a green house experiment was conducted. For this, biocontrol agent T. harzianum UBSTH-501 was applied as seed treatment, whereas MeJA (150 mg L(–1)) was applied 5 days prior to pathogen inoculation. …”
Publicado 2019
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535155por McLennan, Stuart“…Overall, this study indicates that Swiss PRWs are not yet a reliable source of unbiased information regarding patient experiences and satisfaction with Swiss physicians; many selected physicians were unable to be identified, only a few physicians had been rated, and the ratings posted were overwhelmingly positive.…”
Publicado 2019
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535156“…Kirkpatrick’s reaction was measured through subject completion of a survey on satisfaction with the learning experiences and an evaluation of training. RESULTS: A total of 69 medical students participated in the study. …”
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535157“…To determine the generalized effect of (12)C ion and olaparib in inhibition of cell’s metastatic potential, wound healing and activity of MMP-2, − 9 was also studied in HeLa and MCF7 cell lines after (12)C ion exposure and in combination with PARP-1 inhibitor olaparib. RESULTS: Our experiments show that (12)C ion and PARP-1 inhibition separately reduces cell proliferation, cell migration, wound healing, phosphorylation of EGFR, Akt, p38, ERK resulting inactivation of NF-kB. …”
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535158por Liu, Ruifeng, Wei, Shihong, Zhang, Qiuning, Zhang, Xueliang, Luo, Hongtao, Tian, Jinhui, Li, Yi, Ge, Long, Wang, Xiaohu“…BACKGROUND: Preclinical in vitro experiments demonstrated that epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) might have synergistic effect in combination with radiotherapy on Non-small cell lung cancer (NSCLC), but the clinical trials showed inconsistence results in NSCLC patients with EGFR status unknow or mutations. …”
Publicado 2019
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535159por Pérez-Pérez, Martín, Pérez-Rodríguez, Gael, Fdez-Riverola, Florentino, Lourenço, Anália“…Furthermore, sentiment analysis enabled a closer look into the opinions expressed in the tweets, namely, gaining a deeper understanding of patients’ feelings and experiences. RESULTS: Health organizations received most of the communication, whereas BD patients and experts in bowel conditions and nutrition were among those tweeting the most. …”
Publicado 2019
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535160por Wu, Yanju, Zheng, Qianqian, Li, Yan, Wang, Guang, Gao, Shuting, Zhang, Xiaodong, Yan, Xu, Zhang, Xinwen, Xie, Jisheng, Wang, Yuanyuan, Sun, Xun, Meng, Xin, Yin, Bo, Wang, Biao“…The relationships among Yap1, TEADs and CCNE1/2 were predicted and evaluated using bioinformatics, dual-luciferase reporter and co-immunoprecipitation (Co-IP) assays. For in vivo experiments, a xenograft model was used to investigate the effects of metformin on the proliferation of BLCA cells. …”
Publicado 2019
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