“…MiR-106a overexpression resulted in a decrease in RUNX3 expression, and miR-106a silence increased RUNX3 expression. Rescue experiments conducted with miR-106a inhibitor restored radiation resistance and reduced DNA damage in radiation condition. …”
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“…Sufficient trust and shared lived experiences made discussions easier. Mentees have multifaceted needs; however, mentors stated that an app resource that provided self-training, resources, support from other mentors, and tips for better mentoring could prove beneficial. …”
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“…METHODS: Following best-practice standards for stated-preference research, a survey employed a discrete choice experiment (DCE) and contingent-valuation (CV) questions to quantify respondents’ trade-off preferences for vaccines that protect against diseases with various levels of severity and incidence, and to estimate the monetary value of receiving additional consultation regarding MenB vaccination with healthcare providers. …”
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“…The main reasons for using combination vaccines were to reduce the number of injections (96%); ensure the infant is up-to-date with vaccinations (86%); and reduce the pain that the infant experiences with multiple injections (68%). More than half reported that their institution or practice has a program to incentivize infant vaccination according to schedule. …”
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“…The present study aimed to assess the different CA modules in rice-based cropping systems for energy conservation, energy productivity, and to define energy-economic relations. A field experiment consisted of four different tillage-based crop establishment practices (puddled-transplanted rice followed by (fb) conventional-till maize/wheat (CTTPR-CT), non-puddled transplanted rice fb zero-till maize/wheat (NPTPR-ZT), zero-till transplanted rice fb zero-till maize/wheat (ZTTPR-ZT), zero-till direct-seeded rice fb zero-till maize/wheat (ZTDSR-ZT)), with two residue management treatments (residue removal, residue retention) in rice–wheat and rice–maize rotations were evaluated for energy budgeting and energy-economic relations. …”
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“…BACKGROUND: Emotional intelligence (EI) and mindfulness can impact the level of anxiety and depression that an individual experiences. These symptoms have been exacerbated among college students during the COVID-19 pandemic. …”
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“…Compared with vehicle group, the ex vivo experiments showed that short-term Desferal® administration could promote the potential of BMSC growth (proliferation and colony formation ability) and improve the rebalance of osteogenic and adipogenic differentiation, as well as rejuvenate senescent BMSCs (ROS level and SA-β-gal staining) and revise the expression of stemness/senescence-associated genes. …”
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“…Co-immunoprecipitation experiments were performed to examine the interaction between the LD2-LD3-LD4 polypeptide and FAK. …”
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“…Gain- and loss-of-function experiments were performed in HeLa cells to evaluate the effect of miR-454-3p or linc00887 on the expression of FERM domain containing protein 6 (FRMD6) protein and several key proteins in the FRMD6-Hippo signaling pathway. …”
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“…R. coriaria (as a powder) was administered through the diet at two concentrations (low dose: 0.1% (w/w) and high dose: 1 % (w/w)) for the duration of the experiment in a syngeneic 4T1 mouse and chemically-induced rat mammary carcinoma models. …”
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“…The super fine Al powder was prepared by electrical explosion method, and encapsulated in situ by selected fluorine rubber F2311. The experiments on thermal stability demonstrated F2311 coating thickness should be no less than 3.6 nm. …”
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“…OBJECTIVE: The objective of this paper is to summarize lessons learned from primary care professionals involved in a pioneering pilot project in Switzerland for the systemwide implementation of shared electronic medication plans. We collected experiences, assessed the influences of the local context, and analyzed underlying mechanisms influencing the implementation. …”
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“…ABSTRACT: Continental crossbred beef heifers were used in a randomized complete block design experiment to evaluate the effects of replacement of dry-rolled corn with unprocessed rye on the finishing-phase growth performance and efficiency of dietary net energy (NE) use. …”
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“…ABSTRACT: A 2 × 6 factorial experiment was conducted to determine the influences of dietary metabolizable energy (ME) and methionine (Met) levels on growth performance, carcass traits, and plasma biochemical parameters of starter Pekin ducks from 1 to 21 days of age. …”
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“…Body weight was registered and then all birds were slaughtered; samples from the small intestine and caecum were collected at 4- and 7-days post infection. The experiment lasted eleven days. Villi height and crypt depth ratios of the duodenum, jejunum and ileum were evaluated using appropriate software, while reverse transcription quantitative PCR (RT-qPCR) was utilized for assessing transcript levels of key cecal inflammatory cytokines (IL-1β, IL-18, IL-17, IL-15, IL13 and IL-4). …”
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“…Here we elucidated the roles of E-sel in AML survival using human AML cell lines and patient-derived AML xenograft (PDX) models. In our experiments, E-sel decreased CDK4/6 expression and increased dormancy of AML cells in vitro. …”
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“…These findings can help design in vitro experiments and possibly facilitate a vaccine design and successful antiviral strategies.…”
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“…Process measures related to the participants' experiences and perceptions of the exercise program and web-based app were also included. …”
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“…Our objective was to evaluate the effect of PC and MVS on performance of steers. The experiment used a 2 × 2 factorial arrangement design, considering a 26-d PC treatment from weaning to transport to the feedlot (day 0), and injectable MVS on days −45, −26, and 0. …”
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“…METHODS: Apixaban was added to the CRRT circuit and serial pre-filter bovine blood samples were collected along with post-filter blood and effluent samples. All experiments were performed in duplicate using continuous veno-venous hemofiltration (CVVH) and hemodialysis (CVVHD) modes, with varying filter types, flow rates, and point of CVVH replacement fluid dilution. …”
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