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535421“…Furthermore, no adverse effects were observed in turmeric extract adjunctively supplemented rabbits, and the provided dose regimen of these supplements was found to be safe. ABSTRACT: In this experiment, the protective effect of turmeric extract (TE) on side effects of Ivermectin-treated rabbits, while improving their performance, blood characteristics, and antioxidant status, was investigated. …”
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535422por Shelby, Tyler, Caruthers, Tyler, Kanner, Oren Y, Schneider, Rebecca, Lipnickas, Dana, Grau, Lauretta E, Manohar, Rajit, Niccolai, Linda“…OBJECTIVE: We pilot tested 2 separate Bluetooth contact tracing technologies on a university campus to evaluate their sensitivity and specificity, and to learn from the experiences of the participants. METHODS: We used a convergent mixed methods study design, and participants included graduate students and researchers working on a university campus during June and July 2020. …”
Publicado 2021
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535423por Baker, Venetia, Arnold, Georgia, Piot, Sara, Thwala, Lesedi, Glynn, Judith, Hargreaves, James, Birdthistle, Isolde“…OBJECTIVE: We sought to identify Alone Together viewer’s perspectives on the global COVID-19 pandemic and national lockdowns by examining the words, conversations, experiences, and emotions expressed on social media in response to the Alone Together episodes. …”
Publicado 2021
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535424“…Furthermore, lncRNA MEG8 knockdown upregulated miR-203 (P<0.01) expression, but did not alter miR-34a or miR-200b expression (both P>0.05). Subsequent experiments revealed that miR-203 silencing exerted no significant effect on the expression levels of lncRNA MEG8 (P>0.05) in HemECs. …”
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535425por Zhou, Xin, Li, Tian-Man, Luo, Jian-Zhu, Lan, Chen-Lu, Wei, Zhong-Liu, Fu, Tian-Hao, Liao, Xi-Wen, Zhu, Guang-Zhi, Ye, Xin-Ping, Peng, Tao“…The inhibition of CYP2C8 over-expression on PI3K/Akt/p27(Kip1) axis was subsequently demonstrated with Western blot assay. In the rescue experiment, it was observed that both P27 inhibitor and PI3K agonist counteracted the repressed malignant phenotype caused by CYP2C8 over-expression, which further demonstrated that CYP2C8 played a role in HCC cells via PI3K/Akt/p27(Kip1) axis. …”
Publicado 2021
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535426“…Psychological measures were administered to evaluate the feasibility of the trial methods and included the UCLA Loneliness Scale, the 4-item Perceived Stress Scale, a 1-item COVID-19 distress measure, the Flourishing Scale, and the Scale of Positive and Negative Experiences. RESULTS: The study recruited 30 participants (15 per group). …”
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535427“…RESULTS: MiR-345-5p expression displayed lower level in lung adenocarcinoma tissues (0.241 ± 0.095 vs.1.000 ± 0.233, t = 19.247, P < 0.001) and cell lines (F = 56.992, P < 0.001) than control tissues and cells. Functional experiments demonstrated that upregulation of miR-345-5p inhibited the malignant phenotypes of lung adenocarcinoma cells via suppressing cell proliferation, migration, invasion, and facilitating cell apoptosis. …”
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535428por Giang, Wayne C W, Bland, Emma, Chen, Jeffrey, Colón-Morales, Coralys M, Alvarado, Michelle M“…Individuals who scored lower on the pre-experiment knowledge test focused on different decision factors and were more conflicted about their final enrollment decisions than those with higher knowledge test scores. …”
Publicado 2021
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535429por Briggs, Farren Basil Shaw, Mateen, Farrah J., Schmidt, Hollie, Currie, Keisha M., Siefers, Heather M., Crouthamel, Slavka, Bebo, Bruce F., Fiol, Julie, Racke, Michael K., O'Connor, Kevin C., Kolaczkowski, Laura G., Klein, Phyllis, Loud, Sara, McBurney, Robert Nicholas“…METHODS: Between 3/2021 and 6/2021, participants in iConquerMS, an online people-powered research network, reported SARS-CoV-2 vaccines, experiences of local (itch, pain, redness, swelling, or warmth at injection site) and systemic (fever, chills, fatigue, headache, joint pain, malaise, muscle ache, nausea, allergic, and other) reactions within 24 hours (none, mild, moderate, and severe), DMT use, and other attributes. …”
Publicado 2021
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535430“…METHOD: MPE researchers conducted four online focus groups in Europe examining the views and experiences of myeloma and AL amyloidosis patients and caregivers during the COVID-19 pandemic. …”
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535431“…They also feature a second [Cu(diMesbpy)](+) coordinated to the nominally tridentate tripy binding site in a four-coordinate hypodentate κ(2)-fashion. Competition experiments with model complexes showed that the binding strength of the bidentate pytri is similar to that of the κ(2)-tripy ligand, leading to the lack of selectivity. …”
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535432por Lai, Pin-Kuang, Ghag, Gaurav, Yu, Yao, Juan, Veronica, Fayadat-Dilman, Laurence, Trout, Bernhardt L.“…These domain swapped IgG4 S228P molecules also showed reduced viscosity from experiment and coarse-grained simulations. We also observed that experimental diffusion interaction parameter (kD) values have a high correlation with computational diffusivity prediction for both IgG1 and IgG4 S228P isotypes. …”
Publicado 2021
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535433por Schmidtlein, Paula Marie, Volz, Clara, Hackel, Alexander, Thürling, Isabel, Castven, Darko, Braun, Rüdiger, Wellner, Ulrich Friedrich, Konukiewitz, Björn, Riemekasten, Gabriela, Lehnert, Hendrik, Marquardt, Jens-Uwe, Ungefroren, Hendrik“…We further show that inhibition of RAC1 activation attenuated pluripotency marker expression and self-renewal ability, while depletion of RAC1b dramatically enhanced stemness features and clonogenic potential. Finally, rescue experiments involving pharmacological or RNA interference-mediated inhibition of RAC1 or RAC1b, respectively, confirmed that both RAC1 isoforms control the deTDtP in an opposite manner. …”
Publicado 2021
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535434por Redaelli, Veronica, Bosi, Alice, Luzi, Fabio, Cappella, Paolo, Zerbi, Pietro, Ludwig, Nicola, Di Lernia, Daniele, Roughan, John Vincent, Porcu, Luca, Soranna, Davide, Parati, Gianfranco, Calvillo, Laura“…Physiological alterations were recorded via body weight changes and assessing the temperature of Brown Adipose Tissue (BAT) using infra-red thermography (IRT), and at the end of the experiment we determined the concentration of cytokines CXCL12 and CCL2 in bone marrow (BM) and activated microglia in the brain. …”
Publicado 2021
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535435por Ciriaco, Francine M, Henry, Darren D, Beierbach, Romina, Schulmeister, Tessa M, Ruiz-Moreno, Martin, Garcia-Ascolani, Mariana E, Podversich, Federico, Dubeux, Jose C B, DiLorenzo, Nicolas“…An experiment was designed to evaluate the effects of CaO on ruminal in situ degradability (RISD) of forage components and in vitro organic matter digestibility (IVOMD) of warm-season forages. …”
Publicado 2021
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535436por Xu, Xiaoqin, Zhang, Juan, Chen, Liang, Sun, Yu, Qing, Degang, Xin, Xuelei, Yan, Chunyan“…Serum and colon tissue samples were collected from the mice during the experiment, and survival signs, body weight changes, disease activity index (DAI), colon length, and colon wet weight in mice were determined after the treatment. …”
Publicado 2021
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535437por Liu, Zhengli, Gong, Maofeng, Zhao, Boxiang, Gu, Jianping, Su, Haobo, Zhou, Yangyi, Fu, Guanqi, He, Xu, Kong, Jie“…This article summarizes the specific methods and key points of this technology. Methods: The experiment studied a rabbit that was anesthetized through the vein. …”
Publicado 2021
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535438por Xia, Ya-Ru, Wei, Xiao-Cui, Li, Wen-Shi, Yan, Qiu-Jin, Wu, Xiu-Lin, Yao, Wei, Li, Xu-Hang, Zhu, Fan“…Moreover, NDUFV2P1 was increased and demonstrated a significant positive correlation with ERVWE1 and a negative correlation with NDUFV2 in schizophrenia. In vitro experiments disclosed that ERVWE1 suppressed NDUFV2 expression and promoter activity by increasing NDUFV2P1 level. …”
Publicado 2021
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535439por Romero, Carlos, Nardoia, Maria, Brenes, Agustín, Arija, Ignacio, Viveros, Agustín, Chamorro, Susana“…ABSTRACT: Grape seeds (GS) and grape skins (GK) are natural sources of polyphenols with antioxidant capacity. An experiment was conducted to investigate in chickens the effect of including GS and GK (40 g/kg), individually or combined in different proportions (20 g/kg GS–20 g/kg GK; 30 g/kg GS–10 g/kg GK; 10 g/kg GS–30 g/kg GK), in a corn-soybean diet on growth performance, ileal and excreta contents of total extractable polyphenols (TEP) and tannins, ileal digestibility of protein, plasma and meat α-tocopherol concentration and lipid oxidation (assessed by measuring the thiobarbituric acid reactive substances, TBARS) of stored thigh meat. …”
Publicado 2021
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535440por Kopacz, Magdalena, Drażbo, Aleksandra Alicja, Śmiecińska, Katarzyna, Ognik, Katarzyna“…The birds had ad libitum access to feed and water throughout the study. During the experiment, the birds were fed isonitrogenous and isocaloric diets in mash form, with various protein sources. …”
Publicado 2021
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