“…For researchers, consideration for the animals may be reduced to cases included in the experiment. Despite the potential for animal reification, it is partly mitigated in this context by the commonly held belief that animal suffering should be reduced as much as possible. …”
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“…In addition to UTAUT2 variables, we measured self-reported self-efficacy, eHealth literacy, previous experiences with health apps, perceived threat to privacy, and protection motivation as additional determinants of mHealth acceptance. …”
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“…RNA-protein interaction analyses and in vitro translation experiments showed that GAIT and VAIT elements do not compete with each other, highlighting differences between the two pathways. …”
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“…MiR-212-5p mimic and pc DNA-SOCS5 were transfected into liver cancer HepG2 cells alone or in combination, and the cells were randomly divided into four groups, the control group, mimic group, SOCS5 group and mimic + SOCS5 group for subsequent experiments. The orthotopic xenograft mouse models were established by using HepG2 cells in BALB/c athymic nude mice. …”
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“…Gene set enrichment, multi experiment matrix (MEM), and protein-protein interaction (PPI) network analyses were performed to identify the most enriched signaling pathways and SERPINE1-related module genes. …”
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“…Compound-disease-target regulatory network analysis showed that AKT1, IL-6, TNF-α, TP53, VEGFA, and APP were related to the treatment of IS with SHD. Animal experiments demonstrated that SHD significantly reduces the neurological function of rat defect symptoms (P < 0.05), the area of cerebral avascular necrosis, and neuronal necrosis while increasing the levels of IL-6 and APP proteins (P < 0.05) and reducing the levels of AKT1 and VEGFA proteins (P < 0.05). …”
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“…BACKGROUND: Young sexual and gender minorities (SGMs) of color may face unique experiences of discrimination based on their intersectional positions (eg, discrimination based on both racial or ethnic identity and sexual identity). …”
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“…Adolescence represents a period of significant neurodevelopment during which adverse experiences can lead to prolonged effects on disease vulnerability, including effects that can impact future offspring. …”
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“…METHODS: We assessed endosomal TLR expression in total NK cells by using RT-qPCR and western blotting technique. In some experiments, we purified CD56(bright)CD16(−) and CD56(dim)CD16(+) cells subsets by using NK Cell Isolation Kit Activation marker, cytokine production, CD107a expression and cytotoxicity assay were evaluated by flow cytometry. …”
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“…The limitations include the dearth of data that explores the experiences of patients and providers and evaluates programme effectiveness. …”
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“…We find that knockdown of C/EBPβ in cachexia‐inducing Lewis lung carcinoma cells restores myogenic differentiation (+25%, P < 0.0001) and myotube diameter (+90%, P < 0.0001) in conditioned medium experiments and, in vivo, prevents muscle wasting (−51% for small myofibres vs. controls, P < 0.01; +140% for large myofibres, P < 0.01). …”
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“…However, analyzing the effect of ghrelin in the rodent VTA on MAPK activation with ex vivo experiments, on somatodendritic dopamine release with in vivo microdialysis and on the activation of dopaminergic cells with patch-clamp electrophysiology, provided evidence for a predominant role of GHS-R1a:GHS-R1b:D1R oligomers in the rodent VTA as main mediators of the dopaminergic effects of ghrelin. …”
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“…Therefore, the impacts of different tillage and crop residue incorporation managements on soil bacterial community under the double-cropping rice cropping system in southern of China were studied by using phospholipid fatty acids (PLFAs) profile method in the present paper. The experiment included four different tillage treatments: rotary tillage without crop residue input as a control (RTO), no-tillage with crop residue retention (NT), rotary tillage with crop residue incorporation (RT), and conventional tillage with crop residue incorporation (CT). …”
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“…Under simulated hypoxia, roles of Kcnn1 and Tet1 in angiogenesis and Hadh, Tet1, and Kcnn1 in apoptosis were further confirmed with our validation experiments. Conclusion: Roles of m(6)A-modified mRNA transcripts in the context of MI were preliminarily verified. …”
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“…Such variability may be influenced by a range of factors including their early life experiences, genetic selection, and individual cat and human characteristics, in addition to various factors associated with their social and physical environment. …”
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“…We conducted and reported results from 3 experiments that assessed the QMOHI tool in terms of its scalability, generalizability in health topics, and robustness to changes in universities’ website structure. …”
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“…Mice were housed in a gnotobiotic facility during the experiment. Three weeks following colonization, colitis was induced in half of the mice by three cycles (5 d each; 2.0%, 1.5% and 1.5%, respectively) of DSS in drinking water with a 5-d wash-out period between cycles. …”
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“…We gathered data on 93 patients at admission to the intensive care unit and our experiments show that machine learning methods can reach an accuracy comparable with Baux scores in calculating the risk of fatal outcomes. …”
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“…METHODS: An ACA-positive recurrent miscarriage mouse model and normal pregnancy mouse model were adopted in this experiment. Seventy CBA/J female mice were induced to establish the ACA-positive recurrent model; the mice were mated with DBA/2 male mice. …”
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“…METHODS: An animal experiment was carried out to evaluate the accuracy of (131)I activity quantification in mouse kidneys (mean tissue volume of 0.140 mL) using a micro-SPECT system against conventional ex vivo gamma counting (GC) in a NaI(Tl) detector. …”
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