“…Dissemination and implementation science researchers can also benefit from measurement experiences of school health researchers. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s43058-021-00169-y.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ACRH was fractionated into quinone-rich fraction (QRF) and further isolated to yield benzoquinonoid compound (BQ), respectively. In vitro experiments using VEGF-induced human umbilical vein endothelial cells (HUVECs) and IL-1β-induced human fibroblast-like synoviocytes for rheumatoid arthritis (HFLS-RA) were performed to evaluate the effects of these samples on VEGF-induced HUVECs proliferation and tube formation, and towards IL-1β-induced HFLS-RA proliferation, invasion, and apoptosis, respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings provide insights into real-world experiences and the many facets of HRQoL that are important to patients with HAE-C1INH. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In silico or in vitro experiments were applied to determine the pathogenicity of novel variants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Initially, dose response experiments yielding inhibitory concentration 50 (IC(50)) values were performed using MCF-7, HCC1937, and JIMT-1 breast cancer, and the MCF-10A normal-like breast cell lines to get an understanding of toxic ranges. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thus, we hypothesized that ODSH can attenuate the bacterial burden and inflammatory lung injury in CF and we conducted experiments to determine the underlying mechanisms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When challenged ex vivo with EP, spleen mononuclear cells from elastase-exposed mice exhibited dose-dependent production of IFNγ and IL-17, suggesting immune reactivity. In co-culture experiments with splenic CD4(+) T cells isolated from elastase-exposed mice, AAT-Fc treatment prior to EP-priming of bone marrow-derived dendritic cells inhibited the production of IFNγ and IL-17. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The use of Gd(2)O(3):Eu@PVA and (18)F-FDG also assisted intraoperative detection of tumors that were omitted by preoperative positron emission tomography (PET) imaging. Further experiment of image-guided surgery demonstrated feasibility of image-guided tumor resection using Gd(2)O(3):Eu@PVA and (18)F-FDG. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The objective of this study was to understand how individual experiences for all HCWs during the pandemic were associated with perceptions of access to, and receipt of COVID testing . …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Of them, luciferase assay experiment further confirmed that the allele T of g.17307103A > T significantly increased the transcriptional activity of HTR1B gene than allele A (P = 0.0007). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Repeated nitroglycerin injection-treated mice were used as a CM animal model in the experiment. To identify the distribution and cell localization of GLP-1R in the TNC, we performed immunofluorescence staining. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: At the end of the experiment, left and right ventricular end-diastolic areas were greater in animals treated with high compared to standard fluid administration, regardless of PEEP decrease rate. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, we functionally verified our genomic results using gene knockdown experiments in a human primary cell type that is critical for adipose tissue function. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…An in vitro fermentation experiment was performed using mixture of rumen fluid collected from two cannulated Holstein steers (450 ± 30 kg) and artificial saliva buffer mixed as 1:3 ratio for 12 h incubation time. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, results from in vitro experiments were extrapolated to publicly available datasets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: ECG interpretation using clinical vignettes devoid of real patient experiences does not appear to have as great an impact on ECG diagnostic accuracy as prior clinical exposure. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, BK restrained the H(2)O(2)-induced cell autophagy by decreasing LC3II/I, Beclin1, and ATG5 expression and increasing P62 expression. In the in vivo experiment, the transplanted BK- or 3-MA-treated hCPCs were found to be more effectively improved cardiac function by decreasing cardiomyocyte apoptosis, inflammatory infiltration, and myocardial fibrosis, and promoting neovascularization in the infarcted heart, compared to untreated-hCPCs or c-kit(-) cardiomyocytes (CPC(-) cells). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The antitumor activity of DTX@HNT/Au-SORT (apoptosis of 90 ± 0.3%) was confirmed by in vitro experiments using a caov-4 (ATCC HTB76) cell line (sortilin expression > 70%) that was successfully targeted by the sortilin 2D8-E3 mAb, tagged on the DTX@HNT/Au. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the double luciferase activity detection and RIP experiment confirmed that there was targeted regulation among them (P < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To confirm the involvement of miR-1-3p silencing in abnormal ossification through SOX9, we also performed a rescue experiment in which SOX9 silencing restored the low expression of RUNX2 and collagen type X produced by downregulated miR-1-3p expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso