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  1. 535861
    “…The selected research articles constituted 722 independent experiments evaluating 502 plant species. Of the 722 studies, 81.9%, 12.4%, and 5.5% were in vitro, in vivo, and combined in vitro and in vivo, respectively. …”
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    Antiplasmodial, antimalarial activities and toxicity of African medicinal plants: a systematic review of literature
  2. 535862
    “…Bioinformatics tools and luciferase reporter assays were utilized to identify the potential mechanisms of action. Moreover, rescue experiments were applied to explore whether ZFP36L1 mediated the effects of miR-182-5p in NPC. …”
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    The oncogenic role of HIF-1α/miR-182-5p/ZFP36L1 signaling pathway in nasopharyngeal carcinoma
  3. 535863
    “…BACKGROUND: Advance Care Planning (ACP) has emerged to improve end-of-life processes and experiences. However, the available evidence presents the gloomy picture of increasing number of older people living with chronic diseases and the mismatch between their preferences for and the actual place of death. …”
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    Efficacy of Normalisation of Advance Care Planning (NACP) for people with chronic diseases in hospital and community settings: a quasi-experimental study
  4. 535864
    “…CCK8, colony formation and FACS were used to analyze proliferation of colorectal cancer (CRC) cells. Xenograft experiments were used to analyze tumor growth in vivo. …”
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    CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner
  5. 535865
    “…Moue NSCLC allograft experiments were performed on wild type and transgenic mice with either knockout of MG53, or overexpression of MG53. …”
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    MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer
  6. 535866
    “…The function and mechanism of circHMGCS1–016 were further identified via in vivo experiments. The clinical characteristics and prognostic significance of circHMGCS1–016 were analyzed by a retrospective study. …”
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    circHMGCS1–016 reshapes immune environment by sponging miR-1236-3p to regulate CD73 and GAL-8 expression in intrahepatic cholangiocarcinoma
  7. 535867
    “…For α5GABA(A)Rs intervention experiments, L-655,708 and L-838,417 were used to inhibit or activate α5GABA(A)Rs, respectively. …”
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    MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of α5GABA(A) receptors in aged mice
  8. 535868
    “…Therefore, the present experiment was conducted on tomato (cv. Himsona) during 2019–2020 at farmers' fields to improve tomato productivity and quality. …”
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    Modified plant architecture integrated with liquid fertilizers improves fruit productivity and quality of tomato in North West Himalaya, India
  9. 535869
    “…The therapeutic potential of activin-A-treated lung tumor-infiltrating CD4(+) T cells was evaluated in adoptive transfer experiments, using CD4(−/−)-tumor bearing mice as recipients. …”
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    Activin-A impedes the establishment of CD4(+) T cell exhaustion and enhances anti-tumor immunity in the lung
  10. 535870
    “…The discrimination success rate was 100 % in validation experiments. CONCLUSIONS: The results from this study will be invaluable for ensuring the effective and safe uses of Alpinia medicinal products and for the exploration of novel Alpinia species to improve human health. …”
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    Phylogenetic analysis and development of molecular markers for five medicinal Alpinia species based on complete plastome sequences
  11. 535871
    “…Based on these genes, the degree of immune infiltration was evaluated. Cell function experiments suggested that PPP2CB drives the proliferation and migration of BLCA cells. …”
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    Wnt pathway-related three-mRNA clinical outcome signature in bladder urothelial carcinoma: computational biology and experimental analyses
  12. 535872
    “…Fish were reared under normal condition or concurrent exposure to arsenic (2.65 mg L(−1)), and temperature (34 °C) (As + T) stress for 105 days. The experiment was conducted with eight treatments in triplicates. …”
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    Mitigating multiple stresses in Pangasianodon hypophthalmus with a novel dietary mixture of selenium nanoparticles and Omega-3-fatty acid
  13. 535873
    “…We examined changes in workers’ knowledge and confidence in delivering MNCH services through a pre- and posttest survey. Stakeholders’ experiences with the intervention were explored through semistructured interviews that drew on the technology acceptance model to frame contextual factors that shaped the intervention’s acceptability and usability in the work environment. …”
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    Acceptability and Potential Effectiveness of eHealth Tools for Training Primary Health Workers From Nigeria at Scale: Mixed Methods, Uncontrolled Before-and-After Study
  14. 535874
    “…Finally, we incorporated the extensive personal experiences of all the authors regarding issues in the training of CHWs. …”
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    Community health workers at the dawn of a new era: 6. Recruitment, training, and continuing education
  15. 535875
    “…The refractory gene signature was highly enriched with targets of the transcription factor FOXM1. shRNA knockdown experiments demonstrated that the viability of primary AML cells, but not normal CD34+ cells, depended on FOXM1 expression. …”
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    Blast cells surviving acute myeloid leukemia induction therapy are in cycle with a signature of FOXM1 activity
  16. 535876
    “…The bioinformatics, RNA stability, RIP experiments and RNA pull-down assays were used to explore the potential molecular mechanisms. …”
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    N6-methyladenosine reader IMP2 stabilizes the ZFAS1/OLA1 axis and activates the Warburg effect: implication in colorectal cancer
  17. 535877
    “…RESULTS: In the lung model experiments, expiratory flow could be reduced from − 899 ± 9 ml·s(−1) down to − 328 ± 25 ml·s(−1). …”
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    Control of the expiratory flow in a lung model and in healthy volunteers with an adjustable flow regulator: a combined bench and randomized crossover study
  18. 535878
    “…We attribute this improvement to SWAM, by which the wide architecture with attention mechanism gives the model ability to more extensively learn the unique features of different codes, and we prove it by an ablation experiment. Besides, we perform manual analysis of the performance imbalance between different codes, and preliminary conclude the characteristics that determine the difficulty of learning specific codes. …”
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    An explainable CNN approach for medical codes prediction from clinical text
  19. 535879
    “…Our approach is based on fine-tuned BERT, BioBERT, NCBI BERT, and ClinicalBERT using multi-task learning. Further experiments show the effectiveness of knowledge transformation and the ensemble integration of models of two tasks. …”
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    Drug knowledge discovery via multi-task learning and pre-trained models
  20. 535880
    “…Through bioinformatics algorithm, we found lncRNA HCG18 as a ceRNA, might play important roles in MG. Further experiments indicated that HCG18 was overexpressed in MG patients and was a target of miR-145-5p. …”
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    Identification of the regulatory role of lncRNA HCG18 in myasthenia gravis by integrated bioinformatics and experimental analyses
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