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535881por Li, Chengyong, Yan, Tingting, Lou, Zhenkai, Jiang, Zhimin, Shi, Zhi, Chen, Qinghua, Gong, Zhiqiang, Wang, Bing“…The hydrophilicity, pore size, surface morphology, surface roughness, mechanical properties, and release rate of the osteogenic elements of the prepared scaffold were detected and analyzed. In in vitro experiments, Sprague–Dawley (SD) rat bone marrow mesenchymal stem cells (rBMSCs) were cultured on the scaffold to evaluate cytotoxicity, cell proliferation, spreading, and osteogenic differentiation. …”
Publicado 2021
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535882por Giacomelli, Chiara, Jung, Janine, Wachter, Astrid, Ibing, Susanne, Will, Rainer, Uhlmann, Stefan, Mannsperger, Heiko, Sahin, Özgür, Yarden, Yosef, Beißbarth, Tim, Korf, Ulrike, Körner, Cindy, Wiemann, Stefan“…Quantifying cell growth of three TNBC cell lines upon miRNA gain-of-function experiments, we characterised miR-193b as a strong and consistent repressor of proliferation. …”
Publicado 2021
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535883“…Quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) verified the SDG have differences in expression between tumor tissue and normal thyroid tissue. In addition, cell experiments were conducted to observe the changes in cell morphology and expression of signature’s genes with the influence of ferroptosis induced by sorafenib. …”
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535884por Ma, Yun, Guo, Guijie, Li, Tingting, Wen, Faxin, Yang, Jianling, Chen, Biao, Wang, Xuefei, Chen, Ji-Long“…Depletion of lncRNA-IUR1 promoted survival of Abl-transformed human leukemic cells in experiments in vitro and xenografted tumor growth in mice, whereas ectopic expression of lncRNA-IUR1 sensitized the cells to apoptosis and suppressed tumor growth. …”
Publicado 2022
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535885por Arunachalam, Divya, Ramanathan, Shruthi Mahalakshmi, Menon, Athul, Madhav, Lekshmi, Ramaswamy, Gopalakrishna, Namperumalsamy, Venkatesh Prajna, Prajna, Lalitha, Kuppamuthu, Dharmalingam“…METHODS: Human corneal epithelial cell line and primary cultures were grown in a six-well plate and used for coculture experiments. Internalization of the conidia was confirmed by immunofluorescence microscopy of the colocalized endosomal markers CD71 and LAMP1. …”
Publicado 2022
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535886por Li, Peng, Zhao, Yizhu, Yan, Shaojia, Song, Bocheng, Liu, Yongfa, Gao, Mingkun, Tang, Dazhi, Guo, Yuming“…The objective of this experiment was to measure the effects of dietary SS using three dietary treatments on egg-laying performance and immune function of laying hens. …”
Publicado 2022
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535887por You, Yuanhe, Tian, Zhuowei, Du, Zhong, Wu, Kailiu, Xu, Guisong, Dai, Meilu, Wang, Yan’an, Xiao, Meng“…We measured the malignant behaviors of OSCC under the treatment of CM from M1-like TAMs by performing colony forming assays, invasion assays, wound-healing assays, spheroid forming assays and in vivo xenograft experiments. The underlying mechanisms were investigated by RNA-seq, cytokines analysis, intracellular signaling pathway analysis, ChIP assays, bioinformatics analysis and validation. …”
Publicado 2022
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535888por Bedi, Yudhishtar S., Roach, Alexis N., Thomas, Kara N., Mehta, Nicole A., Golding, Michael C.“…Accordingly, defining the processes of germline programming is essential to resolving how the epigenetic memory of paternal experiences transmits to their offspring. Established dogma holds that all facets of chromatin organization and histone posttranslational modification are complete before sperm exits the testes. …”
Publicado 2022
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535889por Chen, Tongqing, Chen, Duan, Chen, Lu, Chen, Zhengxu, Wang, Baolong, Zhou, Daoping“…Prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen (FBG) and thrombin time (TT) of samples were analyzed with blood coagulation analyzers from four different manufacturers(Sysmex, Stago, SEKISUI and Werfen) and their corresponding reagents, respectively. Before the experiment, we also observed whether there were significant differences in coagulation test results of different lots of reagents produced by each manufacturer. …”
Publicado 2022
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535890por Zhang, Lu, Li, Ying, Dong, Yi-Chao, Guan, Chun-Yi, Tian, Shi, Lv, Xiao-Dan, Li, Jian-Hui, Su, Xing, Xia, Hong-Fei, Ma, Xu“…Endometrium thickness, number of glands, and the embryo implantation numbers were improved, and the degree of fibrosis was significantly alleviated by UC-MSCs treatment in the rat model of thin endometrium. In vitro cell experiments showed that UC-MSCs migrated to injured ESCs and enhanced their proliferation. miRNA microarray chip results showed that expression of 45 miRNAs was downregulated in the injured endometrium and upregulated after UC-MSCs transplantation. …”
Publicado 2022
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535891por Rambla, Charlotte, Van Der Meer, Sarah, Voss-Fels, Kai P., Makhoul, Manar, Obermeier, Christian, Snowdon, Rod, Ober, Eric S., Watt, Michelle, Alahmad, Samir, Hickey, Lee T.“…RESULTS: To develop a SPS approach that integrates non-destructive screening for seminal root angle and root biomass, two initial experiments were conducted. Firstly, we demonstrated that transplanting wheat seedlings from clear pots (for seminal root angle assessment) into sand pots (for root biomass assessment) did not impact the ability to differentiate genotypes with high and low root biomass. …”
Publicado 2022
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535892por Choi, Geun Joo, Kang, Hyun, Lee, Oh Haeng, Ahn, Eun Jin, White, Fletcher A., Cho, Ye Jin, Baek, Chong Wha, Jung, Yong Hun, Kwon, Ji Wung“…To compare immature versus mature ROE, the rats were injected with mature ROE 300 mg/kg and immature ROE 300 mg/kg after hyperalgesia development. For all experiments, the mechanical withdrawal threshold(MWT) was evaluated using von Frey filaments before the first acidic saline injection, 24 h after the second injection, and at various time points after drug administration. …”
Publicado 2022
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535893por Zhou, Yang, Wang, Chunyan, Ding, Jinye, Chen, Yingying, Sun, Yaoqi, Cheng, Zhongping“…Bioinformatics analysis revealed that YES1 expression was upregulated in recurrent cisplatin-resistant ovarian cancer tissue, and in vitro experiments also verified its upregulation in cisplatin-resistant cell lines. …”
Publicado 2022
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535894“…The posts were examined for initial patterns, and then those concepts were grouped into themes to reveal the authentic experiences of people living with EDs during the COVID-19 pandemic. …”
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535895“…We conducted evaluations before, immediately after, and 2 weeks after the experiment, based on the scores of written and practical examinations. …”
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535896por Yang, Guo-Jing, Shang, Le-Yuan, Zhou, Xiao-Nong, Lee, Tamsin E., Bi, Bo, White, Michael, Smith, Thomas A., Penny, Melissa A.“…METHODS: We collated data from both published and unpublished malaria parasite inoculation experiments conducted between 1979 and 1988 with parasites from different regions of the People’s Republic of China. …”
Publicado 2022
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535897por Robin, Shannon, Hassine, Khalil Ben, Muthukumaran, Jayaraman, Jurkovic Mlakar, Simona, Krajinovic, Maja, Nava, Tiago, Uppugunduri, Chakradhara Rao S., Ansari, Marc“…With this systematic computational methodology, we provide a rational-, time-, and cost-effective way to identify and prioritize the interesting putative substrates or inhibitors of UGT2B10 for further testing in in vitro experiments. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12860-021-00402-5.…”
Publicado 2022
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535898por Ma, Lifang, Xue, Xiangfei, Zhang, Xiao, Yu, Keke, Xu, Xin, Tian, Xiaoting, Miao, Yayou, Meng, Fanyu, Liu, Xiaoxin, Guo, Susu, Qiu, Shiyu, Wang, Yikun, Cui, Jiangtao, Guo, Wanxin, Li, You, Xia, Jinjing, Yu, Yongchun, Wang, Jiayi“…Cell viability, 3D-spheroid generation, in vivo LUAD formation, experiments in cell- and patient-derived xenograft mice and survival analysis were conducted to explore the impact of m(6)A on LUAD. …”
Publicado 2022
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535899por Whittaker, Jackie L., Truong, Linda K., Losciale, Justin M., Silvester-Lee, Trish, Miciak, Maxi, Pajkic, Andrea, Le, Christina Y., Hoens, Alison M., Mosewich, Amber, Hunt, Michael A., Li, Linda C., Roos, Ewa M.“…Secondary study objectives will assess the feasibility of a future hybrid effectiveness-implementation trial protocol, determine the optimal intervention length, and explore stakeholder experiences. DISCUSSION: This study will assess the efficacy of a novel, virtually-delivered, physiotherapist-guided exercise-based program to optimize knee health in persons at increased risk of osteoarthritis due to a past knee injury. …”
Publicado 2022
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535900por Tóth, Melinda E., Sárközy, Márta, Szűcs, Gergő, Dukay, Brigitta, Hajdu, Petra, Zvara, Ágnes, Puskás, László G., Szebeni, Gábor J., Ruppert, Zsófia, Csonka, Csaba, Kovács, Ferenc, Kriston, András, Horváth, Péter, Kővári, Bence, Cserni, Gábor, Csont, Tamás, Sántha, Miklós“…At the termination of the experiment at month 10, blood was collected for serum low-density lipoprotein (LDL)- and high-density lipoprotein (HDL)-cholesterol measurements and homeostatic assessment model for insulin resistance (HOMA-IR) calculation. …”
Publicado 2022
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