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  1. 535901
    “…Field experiments were conducted to evaluate eight different integrated crop management (ICM) modules for 5 years in a maize-wheat rotation (M(WR)); wherein, ICM(1&2)-ˈbusiness-as-usualˈ (conventional flatbed maize and wheat, ICM(3&4)-conventional raised bed (CT(RB)) maize and wheat without residues, ICM(5&6)-conservation agriculture (CA)-based zero-till (ZT) flatbed maize and wheat with the residues, and ICM(7&8-) CA-based ZT raised bed maize and wheat with the residues. …”
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    Conservation agriculture based integrated crop management sustains productivity and economic profitability along with soil properties of the maize-wheat rotation
  2. 535902
    “…Thirty-eight (21.8%) of the women reported four or more adverse childhood experiences; 46 (31.3%) reported intimate partner violence during their current pregnancy. …”
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    Feasibility of a birth-cohort in Pakistan: evidence for better lives study
  3. 535903
    “…Furthermore, functional experiments, including Transwell assay, 3D multicellular tumor spheroid invasion assay and metastasis models, were performed using circPTEN1 knockdown and overexpression cell lines in vitro and in vivo to investigate the effects of circPTEN1 on tumor metastasis in CRC. …”
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    circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling
  4. 535904
    “…RESULTS: Quality control experiments indicate that EV detected using our flow cytometry method are 0.2 to 1 micron in size. …”
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    CNS endothelial derived extracellular vesicles are biomarkers of active disease in multiple sclerosis
  5. 535905
    “…Screen time was assessed with the Childhood Experiences Questionnaire. Developmental vulnerability versus developmental health in five domains (physical, social, emotional, language and cognition, and communication skills) was measured with the Early Development Instrument. …”
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    Screen time and developmental health: results from an early childhood study in Canada
  6. 535906
    “…We conducted follow-up semistructured interviews to understand EC-HR participant experiences with the intervention. RESULTS: HbA(1c) decreased by 0.41% (4.5 mmol/mol; P=.04) more from baseline to 12 months among participants in the EC-HR group than among those in UC-HR; however, only 61 (32.9%) of 185 EC-HR participants engaged in the program. …”
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    Continuous Glucose Monitoring With Low-Carbohydrate Nutritional Coaching to Improve Type 2 Diabetes Control: Randomized Quality Improvement Program
  7. 535907
    “…This study aims to summarize and condense these experiences through a retrospective analysis in Jiangsu Province, which could be adapted and applied in other malaria elimination settings worldwide. …”
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    Improving the surveillance and response system to achieve and maintain malaria elimination: a retrospective analysis in Jiangsu Province, China
  8. 535908
    “…EC(50) and CC(50) were determined by dose response experiments, and the ratio (EC(50)/CC(50)) was used as a selectivity index (SI) to measure the antiviral vs. cytotoxic activity. …”
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    Searching for plant-derived antivirals against dengue virus and Zika virus
  9. 535909
    “…We used publicly available RNA knockdown data from Cas13 characterization experiments for 555 sgRNAs targeting the transcriptome in HEK293 cells, in conjunction with transcriptome-wide protein occupancy information. …”
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    CASowary: CRISPR-Cas13 guide RNA predictor for transcript depletion
  10. 535910
    “…Th17 lymphocytes associate with active TAK. In-vitro experiments on cultured PBMCs suggest promise for further evaluation of a combination of immunosuppressive tacrolimus with anti-fibrotic tadalafil (or other anti-fibrotic therapies) in clinical trials of TAK.…”
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    Novel Th17 Lymphocyte Populations, Th17.1 and PD1+Th17, are Increased in Takayasu Arteritis, and Both Th17 and Th17.1 Sub-Populations Associate with Active Disease
  11. 535911
    “…Cover letters conveyed different information about the survey’s topics (combat, unwanted sexual attention, or lifetime and military experiences), how Veterans’ names had been selected (list of OEF/OIF/OND Veterans or list of Veterans applying for disability benefits), and what incentive Veterans would receive ($20 or $40). …”
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    Impact of different cover letter content and incentives on non-response bias in a sample of Veterans applying for Department of Veterans Affairs disability benefits: a randomized, 3X2X2 factorial trial
  12. 535912
    “…METHODS: We conducted a series of in vitro (MTT assay, apoptosis, flow cytometry, and RNA sequencing) and in vivo (xenograft ovarian cancer model) experiments to determine the biological effects of BETi combined with AVA in ovarian cancer. …”
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    Targeting CCR2(+) macrophages with BET inhibitor overcomes adaptive resistance to anti-VEGF therapy in ovarian cancer
  13. 535913
    “…We used thematic content analysis based on an interview guide developed following a situational analysis of NCDs care in Zimbabwe and views from patients with lived experiences. RESULTS: Saturation was reached after interviewing 10 participants from five busy urban clinics. …”
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    Barriers to the provision of non-communicable disease care in Zimbabwe: a qualitative study of primary health care nurses
  14. 535914
    “…CircALG1 overexpression promoted the migration and invasion of CRC cells, and circALG1 silencing and reduction of the circALG1 m(6)A modification level inhibited CRC cell migration and invasion. In vivo experiments further confirmed the prometastatic role of circALG1 in CRC. …”
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    The N(6)-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway
  15. 535915
    “…Flow cytometry analysis (FCAS), BrdU labelled experiments, immunofluorescence and immunohistochemical assays were performed to detect the proportion of EpSCs in the epidermis. …”
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    Dendritic epidermal T cells secreting exosomes promote the proliferation of epidermal stem cells to enhance wound re-epithelialization
  16. 535916
    “…BACKGROUND: Globally, there are fundamental shortcomings in mental health care systems, including restricted access, siloed services, interventions that are poorly matched to service users’ needs, underuse of personal outcome monitoring to track progress, exclusion of family and carers, and suboptimal experiences of care. Health information technologies (HITs) hold great potential to improve these aspects that underpin the enhanced quality of mental health care. …”
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    Informing the Future of Integrated Digital and Clinical Mental Health Care: Synthesis of the Outcomes From Project Synergy
  17. 535917
    “…METHODS: A mixed-method sequential explanatory approach using a structured questionnaire followed by focus group discussions (FGDs) to collect information on experiences, views, reasons, how and when LLINs are discarded. …”
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    “In starvation, a bone can also be meat”: a mixed methods evaluation of factors associated with discarding of long-lasting insecticidal nets in Bagamoyo, Tanzania
  18. 535918
    “…Hence, the toxicity of the ultrasmall Fe(3)O(4) nanoparticles should be attributed to both the iron element and size. In the in vitro experiments, all the ultrasmall nanoparticles (< 5 nm) of Fe(3)O(4), SiO(2), and gold induced the generation of the reactive oxygen species (ROS) efficiently, while no obvious ROS was observed in larger nanoparticles groups. …”
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    Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs
  19. 535919
    “…The use of non-genetic biomarkers, however, presents challenges related to counselling, informed consent, communication of results and limited protections afforded by existing legislation. Experiences from pre-symptomatic genetic testing and counselling, and the legal protections against discrimination based on genetic data, may serve as a guide. …”
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    Preventing amyotrophic lateral sclerosis: insights from pre-symptomatic neurodegenerative diseases
  20. 535920
    “…We performed a series of experiments to determine the characteristics and coding capacity of circMAP3K4. …”
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    A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma
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