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535981“…The binding relation between miR-15a-5p and Stat3 was verified via the dual-luciferase reporter gene assay. Functional rescue experiments were performed to probe the underlying role of miR-15a-5p/Stat3/the PI3K-Akt-mTOR pathway in KGN cell autophagy. …”
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535982por Okeke, Sylvester Reuben“…Such conflation leads to situations where nuances and complexities around sex-related experiences are lost or, at most, tangentially investigated. …”
Publicado 2022
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535983por Nuccio, Erin E., Blazewicz, Steven J., Lafler, Marissa, Campbell, Ashley N., Kakouridis, Anne, Kimbrel, Jeffrey A., Wollard, Jessica, Vyshenska, Dariia, Riley, Robert, Tomatsu, Andy, Hestrin, Rachel, Malmstrom, Rex R., Firestone, Mary, Pett-Ridge, Jennifer“…We designed and tested a semi-automated, high-throughput SIP (HT-SIP) pipeline to support well-replicated, temporally resolved amplicon and metagenomics experiments. We applied this pipeline to a soil microhabitat with significant ecological importance—the hyphosphere zone surrounding arbuscular mycorrhizal fungal (AMF) hyphae. …”
Publicado 2022
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535984por Hirashita, Yuka, Fukuda, Masahide, Kodama, Masaaki, Tsukamoto, Yoshiyuki, Okimoto, Tadayoshi, Mizukami, Kazuhiro, Kawahara, Yoshinari, Wada, Yasuhiro, Ozaka, Sotaro, Togo, Kazumi, Kinoshita, Keisuke, Fuchino, Takafumi, Fukuda, Kensuke, Okamoto, Kazuhisa, Ogawa, Ryo, Matsunari, Osamu, Honda, Koichi, Murakami, Kazunari“…We also showed the relationship between eEF1A dimethylation and expressions of reprogramming factors, Oct4 and Nanog, by immunohistochemistry and in vitro genome editing experiments. CONCLUSIONS: The results indicated that H. pylori infection induced eEF1A dimethylation in gastric mucosa. …”
Publicado 2022
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535985“…Finally, in vivo xenograft experiments validated that blocking the SNHG16-mediated miR-506-3p-PTBP1 axis effectively limited 5-Fu-resistant GC cell originated-xenograft tumor growth under 5-Fu treatments. …”
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535986“…At each time point cytotoxicity (LDH assay), cell viability (live/dead staining and confocal microscopy) and cell proliferation (WST1 assay) were assessed. All experiments were repeated a minimum of 3 times using DPSCs isolated from 3 different donors for each time point assessed (n = 9/group). …”
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535987por Niemeyer, Daniela, Stenzel, Saskia, Veith, Talitha, Schroeder, Simon, Friedmann, Kirstin, Weege, Friderike, Trimpert, Jakob, Heinze, Julian, Richter, Anja, Jansen, Jenny, Emanuel, Jackson, Kazmierski, Julia, Pott, Fabian, Jeworowski, Lara M., Olmer, Ruth, Jaboreck, Mark-Christian, Tenner, Beate, Papies, Jan, Walper, Felix, Schmidt, Marie L., Heinemann, Nicolas, Möncke-Buchner, Elisabeth, Baumgardt, Morris, Hoffmann, Karen, Widera, Marek, Thao, Tran Thi Nhu, Balázs, Anita, Schulze, Jessica, Mache, Christin, Jones, Terry C., Morkel, Markus, Ciesek, Sandra, Hanitsch, Leif G., Mall, Marcus A., Hocke, Andreas C., Thiel, Volker, Osterrieder, Klaus, Wolff, Thorsten, Martin, Ulrich, Corman, Victor M., Müller, Marcel A., Goffinet, Christine, Drosten, Christian“…Despite undetectable ACE2 protein expression in NCI-H1299 cells, CRISPR/Cas9 knock-out and antibody-mediated blocking experiments revealed that multicycle spread of B.1 and VOC Alpha required ACE2 expression. …”
Publicado 2022
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535988por Yan, Yan, Chen, Yonghua, Pan, Jiahao, Xing, Wei, Li, Qiang, Wang, Yan, Gei, Liba, Yuan, Yunfei, Xie, Jingdun, Zeng, Weian, Chen, Dongtai“…An HCC xenograft model was established for in vivo experiments. RESULTS: DRD3 mRNA expression was significantly higher in nontumor tissues than in tumor tissues. …”
Publicado 2022
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535989por Zhou, Rong, Ni, Wen, Qin, Chao, Zhou, Yunxia, Li, Yuqing, Huo, Jianping, Bian, Lijuan, Zhou, Aijun, Li, Jianming“…Loss and gain-of-function experiments in vitro and in vivo were used to assess the effects of YTHDF3 on HCC cell proliferation, migration and invasion. …”
Publicado 2022
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535990por Wojniusz, Slawomir, Thorkildsen, Vibeke Dehli, Heiszter, Silje Therese, Røe, Yngve“…As expected, students most regret not meeting real patients and missing out on the new clinical experiences such encounters would provide. CONCLUSIONS: Despite lack of direct patient contact, students in physiotherapy education evaluated that an online alternative placement was highly clinically relevant. …”
Publicado 2022
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535991“…The articles were screened according to inclusion and exclusion criteria, such as study population, intervention method and type of experiment, and 11 articles were ultimately included. …”
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535992por Battling, Svenja, Engel, Tobias, Herweg, Elena, Niehoff, Paul-Joachim, Pesch, Matthias, Scholand, Theresa, Schöpping, Marie, Sonntag, Nina, Büchs, Jochen“…By using solid fructose, we presented a second feeding strategy, which can be of great interest for further scale-up experiments. A first scale-up of this process was performed, showing the possibility for an industrial production of 5-keto-d-fructose. …”
Publicado 2022
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535993“…In addition, it is important to specify the procedures used for fat analyses. Therefore, an experiment was conducted to 1) determine the apparent ileal digestibility (AID) and SID of fat and fatty acids in ten different oil sources for growing pigs and to develop prediction equations for SID of fat based on fatty acid composition; and 2) compare the effect of the fat extraction methods on the calculated values for endogenous loss and digestibility of fat. …”
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535994por Liang, Yanping, Cen, Junjie, Huang, Yong, Fang, Yong, Wang, Yunfei, Shu, Guannan, Pan, Yihui, Huang, Kangbo, Dong, Jiaqi, Zhou, Mi, Xu, Yi, Luo, Junhang, Liu, Min, Zhang, Jiaxing“…RNA pull-down, luciferase reporter assays and FISH experiment were used to confirm the interactions among circNTNG1, miR-19b-3p, and HOXA5 mRNA. …”
Publicado 2022
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535995“…BACKGROUND: Lysine (Lys) is the first limiting amino acid for pigs fed corn-soybean meal diets. Three experiments were conducted to estimate the optimal standardized ileal digestible (SID) Lys requirement for growing (Exp. 1), early finishing (Exp. 2), and late finishing (Exp. 3) pigs under commercial conditions. …”
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535996por Casañas, Rocío, Castellvi, Pere, Gil, Juan-José, Torres-Torres, María, Barón, Jesica, Teixidó, Mercè, Sampietro, Hernán María, Díez, Marta, Fernández, Raúl, Sorli, Raquel, Siñol, Patricia, Jurado, Francisca, Carreras-Salvador, Regina, Vazquez, Davinia, Gonzalez, Sandra, Martín, Maria Isabel Fernandez-San, Raya-Tena, Antonia, Alvarez, Rosa, Amado-Rodriguez, Isaac, López, Luis Miguel Martín-, Alonso, Jordi, Lalucat-Jo, Lluís“…The contact with a person who has experimented mental illness first-hand did not reduce stigma attitudes. …”
Publicado 2022
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535997por Wang, Xue-Jun, Yao, Lin, Zhang, Hong-Yun, Zhu, Ka-Li, Zhao, Jing, Zhan, Bing-Dong, Li, Yi-Ke, He, Xue-Juan, Huang, Cong, Wang, Zhuang-Ye, Jiang, Ming-Dong, Yang, Peng, Yang, Yang, Wang, Guo-Lin, Wang, Sheng-Qi, Dai, Er-Hei, Gao, Hui-Xia, Ma, Mai-Juan“…Bebtelovimab had no significant loss of potency against the Delta and Omicron subvariants. Cell culture experiments showed Omicron subvariants to be less fusogenic and have higher infectivity than D614G and Delta with comparable efficiency. …”
Publicado 2022
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535998por Christensen, Line Due, Huibers, Linda, Bro, Flemming, Christensen, Morten Bondo, Mygind, Anna“…This study aimed to evaluate experiences from the interprofessional team-based collaboration between designated general practitioners and care home staff with regular contact with the designated general practitioners in an urban Danish setting. …”
Publicado 2023
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535999“…CONCLUSIONS: Farmers have established long-term practices and experiences in cultivation, utilization, and conservation of a diverse group of enset landraces to fill their domestic and market purposes in each zone. …”
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536000por Schlett, Christian, Röttele, Nicole, van der Keylen, Piet, Schöpf-Lazzarino, Andrea Christina, Klimmek, Miriam, Körner, Mirjam, Schnitzius, Kathrin, Voigt-Radloff, Sebastian, Maun, Andy, Sofroniou, Mario, Farin-Glattacker, Erik“…We used a semistructured interview guide that consisted of questions about the consultation in which patients were introduced to tala-med, in addition to questions regarding patient perceptions, experiences, and utilization of tala-med. The interviews were recorded, transcribed, and analyzed through framework analysis. …”
Publicado 2022
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