“…Theoretical models can rationalize existing observations, suggest working hypotheses for future experiments, and provide a unifying framework for connecting PTMs with the observed effects. …”
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“…This study designed and synthesized a new PTX-conjugated chitosan film (N-succinyl-hydroxyethyl chitosan containing PTX [PTX-SHEC]) and evaluated its safety and efficiency using in vivo and in vitro experiments. METHODS: The SHEC conjugated with PTX was confirmed by nuclear magnetic resonance (NMR) and Fourier-transform infrared spectroscopy (FT-IR) measurements. …”
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“…Topics included participants’ experiences of using the Web-based solution, barriers and facilitators of self-management, and barriers and facilitators to effective use. …”
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“…Forty-eight hours after the last injection, animals were submitted to SI and, 24-h later, to the NOR test. In a second experiment, independent groups of mice received, before each CBD injection, AM251 (a CB1 receptor inverse agonist, 0.1–0.3 mg/kg), AM630 (a CB2 receptor inverse agonist, 0.1–0.3 mg/kg), or the 5HT1A receptor antagonist WAY100635 (0.1–0.3 mg/kg). …”
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“…The mothers of the infants completed the Short Form of the Oxford and Liverpool Inventory of Feelings and Experiences, which was used to determine their personality dimension scores, and identify schizotypic traits. …”
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“…Early detection of CHR-P in primary care is clinically and cost-effective This talk will also introduce the continuation of this work; a 5-year research programme that will focus on the treatment of individuals with psychotic experiences in primary care settings.…”
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“…Qualitative findings identified participants’ experiences and the most important themes related to benefits of the DMT intervention: enhanced activation, motivation, socialization, and self-awareness. …”
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“…We had measurements of established childhood risk indicators [4]: psychotic-like experiences, non-psychotic DSM diagnoses and social functioning (GAF). …”
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“…Our study sheds light to an important aspect of Latin American cultures, namely the relationship between exceptional experiences and religion in lay people. In developing countries with a lack of mental health services churches might act as important gatekeepers for UHR individuals. …”
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“…These data indicate that evenamide’s Glu antagonism, demonstrated in preclinical experiments, is of value in patients worsening on current antipsychotics. …”
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“…Davis et al., 2013). Future experiments may wish to explore the correlation between eye movement changes induced by oxytocin and facial affect recognition in larger samples.…”
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“…All clients were diagnosed with primary psychosis disorder. Patient experiences & engagement level were measured using a questionnaire & the Singh-O’Brien Level of Engagement Scale. …”
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“…There was a 32% decrease in the density of all CR-ip interneurons (p=0.020, statistical power=0.747) that was driven by the loss of the small CR-ip interneurons (p=0.017, statistical power=0.777) while the densities of the medium and large CR-ip and NPY-ip interneurons were not significantly altered (p=0.078, p=0.436, p=0.125, respectively). Our experiments were also extended to the dorsolateral prefrontal cortex (medial frontal gyrus and superior frontal gyrus) where no significant changes were seen by IHC. …”
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“…Along with effectiveness, it is important to measure engagement (ie, users’ interaction and usage behavior) and acceptability (ie, users’ subjective perceptions and experiences) to help explain how and why apps and wearables work. …”
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“…Metabolomics approach was used to illustrate the global metabolic changes. (13)C isotopomer tracing experiment and Seahorse XF analysis were undertaken to determine the activity of fatty acid oxidation (FAO). qRT-PCR was performed to evaluate the expression of essential FAO genes including CPT1A. …”
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“…OBJECTIVE: The key objective of this paper is to provide a phenomenological account of the mental health challenges and experiences of adolescent new mothers. We explore the role of social support and the absence of empathy plays in depression among pregnant adolescents. …”
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“…In a series of in vitro experiments we found that VEGF165 and HGF regulate production of inflammatory chemokines by human EC. …”
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“…The gamified app contains (1) a series of interactive games and activities to reinforce skill understanding, (2) an in vivo skills coach that cues the participant to use cognitive behavioral therapy skills during real-world emotional experiences, (3) a home challenge module to encourage home-based exposure tasks, (4) a digital reward system that contains digital points and trophies, and (5) a therapist-patient messaging interface. …”
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“…The message sequences included games, requests for advice, questions about students’ own experiences, and peer testimonial videos. We measured baseline mental health characteristics, frequency of replies, completion of sequences and video viewing, appeal to students, and their perception of having benefited from the program. …”
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“…User views were collected by (1) the “think-aloud” approach when participants using the website were asked to talk about their perceptions and feelings in relation to the website, and (2) self-reporting of website experiences through open-ended questionnaires. Data collection and data analysis continued simultaneously, allowing for website iterations between different points of data collection. …”
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