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536741por Charitaki, Stella, Pervanidou, Panagiota, Tsiantis, John, Chrousos, George, Kolaitis, Gerasimos“…Many children and adolescents are exposed to traumatic experiences every year. Over 30% of these children develop a clinical syndrome with emotional, behavioural, cognitive, social, and physical symptoms called post-traumatic stress disorder (PTSD). …”
Publicado 2017
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536742por Avidan, Michael S., Maybrier, Hannah R., Abdallah, Arbi Ben, Jacobsohn, Eric, Vlisides, Phillip E., Pryor, Kane O., Veselis, Robert A., Grocott, Hillary P., Emmert, Daniel A., Rogers, Emma M., Downey, Robert J., Yulico, Heidi, Noh, Gyu-Jeong, Lee, Yonghun, Waszynski, Christine M., Arya, Virendra K., Pagel, Paul S., Hudetz, Judith A., Muench, Maxwell R., Fritz, Bradley A., Waberski, Witold, Inouye, Sharon K., Mashour, George A.“…INTERPRETATION: The administration of a single subanaesthetic dose of ketamine to older adults during major surgery did not show evidence of reducing postoperative delirium, pain, or opioid consumption, and might cause harm by inducing negative experiences. Given current evidence and guidelines related to ketamine and postoperative analgesia, the unexpected secondary findings regarding pain and opioid consumption warrant replication or refutation in subsequent research. …”
Publicado 2017
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536743por Szegedi, Martin, Hinkle, Jacob, Rassiah, Prema, Sarkar, Vikren, Wang, Brian, Joshi, Sarang, Salter, Bill“…A previously described fresh tissue phantom with implanted electromagnetic tracking (EMT) fiducials was used for this experiment. The phantom was animated using a sinusoidal and a real patient‐breathing signal. …”
Publicado 2013
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536744por Bian, Jiang, Zhao, Yunpeng, Salloum, Ramzi G, Guo, Yi, Wang, Mo, Prosperi, Mattia, Zhang, Hansi, Du, Xinsong, Ramirez-Diaz, Laura J, He, Zhe, Sun, Yuan“…In particular, we used a set of keywords to collect Lynch syndrome–related tweets from October 26, 2016 to August 11, 2017 (289 days) through the Twitter public search application programming interface (API). We experimented with two different classification methods to categorize tweets into the following three classes: (1) irrelevant, (2) promotional health information, and (3) laypeople’s discussions. …”
Publicado 2017
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536745por Sampaio, Vanderson de Souza, Rivas, Gustavo Bueno da Silva, Kobylinski, Kevin, Pinilla, Yudi Tatiana, Pimenta, Paulo Filemon Paolluci, Lima, José Bento Pereira, Bruno, Rafaela Vieira, Lacerda, Marcus Vinícius Guimarães, Monteiro, Wuelton Marcelo“…METHODS: Adult females of Anopheles aquasalis used in experiments were three to five days post-emergence. …”
Publicado 2017
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536746por Srivatsa, Sriram, Paul, Mariel C., Cardone, Claudia, Holcmann, Martin, Amberg, Nicole, Pathria, Paulina, Diamanti, Michaela A., Linder, Markus, Timelthaler, Gerald, Dienes, Hans P., Kenner, Lukas, Wrba, Fritz, Prager, Gerald W., Rose-John, Stefan, Eferl, Robert, Liguori, Giuseppina, Botti, Gerardo, Martinelli, Erika, Greten, Florian R., Ciardiello, Fortunato, Sibilia, Maria“…We used the Mann-Whitney U and Kruskal-Wallis tests to correlate tumor levels of EGFR with tumor stage, and the Kaplan-Meier method to estimate patients’ median survival time. We performed experiments in mice lacking EGFR in intestinal epithelial cells (Villin-Cre; Egfr(f/f) and Villin-CreER(T2); Egfr(f/f) mice) or myeloid cells (LysM-Cre; Egfr(f/f) mice) on a mixed background. …”
Publicado 2017
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536747“…CONCLUSION: According to prior studies and our own experiments, PD-L1 in both cancer cells and TILs and PD-1 in TILs are widely observed in cervical cancer patients, indicating that there may be potential to apply PD-1/PD-L1 antibody drugs in cervical cancer. dMMR patients are associated with higher PD-L1 expression compared with pMMR ones, which suggested that PD-1/PD-L1 antibody drugs may work well in dMMR cervical cancer patients. …”
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536748por Prodinger, Peter M., Foehr, Peter, Bürklein, Dominik, Bissinger, Oliver, Pilge, Hakan, Kreutzer, Kilian, von Eisenhart-Rothe, Rüdiger, Tischer, Thomas“…In synopsis with the common experimental use enabling comparison among different studies, this bone offers ideal biomechanical conditions for three point bending experiments. This can be explained by the combination of a superior aspect ratio and a round and long, straight morphology, which satisfies the beam criteria more than other bones tested. …”
Publicado 2018
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536749“…Where evidence of impact was found at the level of individual reviews and review groups it underlined the need for properly resourced and supported processes in order to derive the greatest benefit from the lived experiences of consumers who are willing to be involved. …”
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536750por Somers, Tamara J, Kelleher, Sarah A, Dorfman, Caroline S, Shelby, Rebecca A, Fisher, Hannah M, Rowe Nichols, Krista, Sullivan, Keith M, Chao, Nelson J, Samsa, Gregory P, Abernethy, Amy P, Keefe, Francis J“…Focus group qualitative data included participants’ experiences with pain following transplant, perspectives on ways to cope with pain, and suggestions for pain management for other HCT patients. …”
Publicado 2018
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536751por McCall, Hugh Cameron, Richardson, Chris G, Helgadottir, Fjola Dogg, Chen, Frances S“…Users of Overcome Social Anxiety are self-directed through various CBT modules incorporating cognitive restructuring and behavioral experiments. The intervention is personalized to each user’s symptoms, and automatic email reminders and time limits are used to encourage adherence. …”
Publicado 2018
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536752por Green, Melissa, Linscott, Richard J, Laurens, Kristin R, Tzoumakis, Stacy, Dean, Kimberlie, Badcock, Johanna C, Carr, Vaughan J“…METHODS: Latent profiles of schizotypy were distinguished among 22,137 children (mean age=11.9 years) for whom intergenerational records of health service contact for mental illness and child protection reports were linked to the Middle Childhood Survey (MCS) within the NSW Child Development Study.1 Selected MCS items were used to index schizotypy across six domains (Unusual Experiences, Cognitive Disorganisation, Impulsive Non-conformity, Introversion, Dysphoria and Self-Other disturbance). …”
Publicado 2018
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536753“…However, childhood trauma exposure in general was not significantly associated with psychotic conversion (HR = 1.01, 95% CI: 0.99 - 1.03; Z = 1.51, p = .13), suggesting perhaps that this risk is either mediated by other risk factors or that most specific traumatic experiences may contribute to an enhanced risk of conversion among UHR individuals. …”
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536754por Estrada, Francesc, Ahuir, Maribel, Crosas, Josep Maria, Vilaplana, Claudia, González-Fernández, Alba, Tost, Meritxell, Olasz, Irina, Mesa, Nora, Gago, Estefania, Pàmias, Montserrat, Monreal, José Antonio, Palao, Diego, Labad, Javier“…Psychopathological symptoms in high school students were assessed with the Community Assessment of Psychic Experiences (CAPE). Statistical analyses were performed with SPSS version 21.0. …”
Publicado 2018
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536755por Zhang, TianHong, Li, HuiJun, Tang, YingYing, Li, Chunbo, Woodberry, Kristen, Shapiro, Daniel I, Niznikiewicz, Margaret, Shenton, Martha E, Keshavan, Matcheri S, Stone, William S, Wang, Jijun“…The R21 and R01 collaborations between Harvard Medical School (HMS), MIT, Florida A&M University (FAMU), and SMHC investigators have capitalized on the resources and experiences of the Harvard researchers as members of NAPLS, MIT researchers’ leading role in functional magnetic resonance imaging (fMRI), and FAMU researchers’ expertise in bridging western and Chinese cultures to enhance the existing capacity of Chinese researchers studying the biopsychosocial aspects of CHR. …”
Publicado 2018
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536756por Cullen, Alexis, Fraser, Elizabeth, Fisher, Helen, Roberts, Ruth, Zahid, Uzma, Pariante, Carmine, Zunszain, Patricia, McGuire, Philip, Murray, Robin, Mondelli, Valeria, Laurens, Kristin R“…METHODS: The sample comprised high-risk individuals who presented either multiple antecedents of schizophrenia (developmental delays, psychopathology, and psychotic-like experiences: ASz=21) or a family history of illness (FHx=13), and typically-developing youth with neither antecedents nor a family history (TD=36). …”
Publicado 2018
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536757por Wen, Dong-yue, Lin, Peng, Liang, Hai-wei, Yang, Xia, Li, Hai-yuan, He, Yun, Yang, Hong, Chen, Gang“…In addition, the related genes of CTD-2547G23.4 gathered from The Atlas of Noncoding RNAs in Cancer (TANRIC) database and Multi Experiment Matrix (MEM) were assessed with Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes, Protein Analysis Through Evolutionary Relationships and protein–protein interaction (PPI) networks. …”
Publicado 2018
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536758por Fassio, Anna, Esposito, Alessandro, Kato, Mitsuhiro, Saitsu, Hirotomo, Mei, Davide, Marini, Carla, Conti, Valerio, Nakashima, Mitsuko, Okamoto, Nobuhiko, Olmez Turker, Akgun, Albuz, Burcu, Semerci Gündüz, C Nur, Yanagihara, Keiko, Belmonte, Elisa, Maragliano, Luca, Ramsey, Keri, Balak, Chris, Siniard, Ashley, Narayanan, Vinodh, Ohba, Chihiro, Shiina, Masaaki, Ogata, Kazuhiro, Matsumoto, Naomichi, Benfenati, Fabio, Guerrini, Renzo“…Both mutations decreased v-ATPase recruitment to autophagosomes, with no major impact on autophagy. Experiments performed on patients’ lymphoblasts using the LysoSensor™ probe revealed lower pH of endocytic organelles for p.Asp349Asn and a reduced expression of LAMP1 with no effect on the pH for p.Asp100Tyr. …”
Publicado 2018
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536759por Deng, Kai, Zeng, Jijiao, Cheng, Gang, Gao, Jian, Sale, Kenneth L., Simmons, Blake A., Singh, Anup K., Adams, Paul D., Northen, Trent R.“…Small-angle neutron scattering experiments showed that these substrates form micelles in solution. …”
Publicado 2018
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536760“…In particular, spontaneously occurring, socio-positive affiliative behaviors (e.g., social coordination and cohesion) that may be indicative of positive emotional experiences have rarely been reported or studied deliberately in zebrafish. …”
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